Abstract: A surgical fluid management system includes a source of surgical media, a surgical instrument, a first pump, one or more filters, a second pump, and a controller. The first pump is operatively coupled between the source of surgical media and the surgical instrument. The one or more filters are configured to filter bodily discharge from a surgical site. The second pump is operatively coupled between the one or more filters and the first pump. The controller is in electrical communication with the first pump and the second pump to control the first and second pumps.

Abstract: An assembly for the treatment of wounds comprising a device for generating a plasma, or an excited gas or gas mixture, respectively. A covering is used to cover a wound area. A first conduit connects the device and the covering and a second conduit connects the covering and a pump. The device is arranged within a housing comprising an opening. The device comprises a piezoelectric transformer having a high-voltage end for generating the plasma, and is arranged within the housing such that the high-voltage end is directed towards the opening. The plasma or the excited gas or gas mixture, respectively, is generated in a region of the opening of the housing. A wound cover comprising a means for guiding the plasma across the wound area is arranged between the covering and the wound area.

Abstract: An arrangement comprising an optical element and an indication member for a drug delivery device is provided. The indication member comprises a plurality of indicia. The optical element comprises an imaging section and a light-transmissive non-imaging section, wherein the indication member is movable with respect to the optical element such that the indicia can be successively moved into a display position relative to the optical element. The imaging section is configured such that, when a first indicium is arranged in the display position, the first indicium is imaged by the imaging section into an imaging solid angle. The non-imaging section is configured such that light defining a second indicium is deflected by the non-imaging section such that the second indicium cannot be identified by a user in the imaging solid angle on a viewing side of the optical element.

Abstract: A balloon resection method is disclosed generally including inserting a catheter with at least one balloon having an outer wall with a resecting, non-slip surface for resecting unwanted biological material, such as tissues or tumors, and supplying fluid thereto in pulsed fashion to repeatedly deflate and inflate the balloon. In certain embodiments, a pump controls the pulsed supply of fluid based on an established frequency or change in volume. In some embodiments, the a keyed connector is used to identify the balloon type, and in some cases, intra-lumen diameters and densities are calculated. In some embodiments, the balloon portion of the catheter includes multiple balloon segments, which in some cases, are inflatable separately from one another.

Abstract: The present invention relates to a display arrangement for a drug delivery device, comprising: a first display member comprising numerous surface portions having at least two different but interrelated appearances and being alternately arranged along a first direction, and a second display member comprising a light modulating structure to modulate visible light emanating from the first display member, wherein first and second display members are movably disposed relative to each other along the first direction to simultaneously reveal and/or to conceal at least two surface portions of interrelated appearance.

Abstract: A catheter insertion device which employs back-and-forth longitudinal axial movement to advance the catheter by the cooperative interface of an incline ramp and a decline ramp with a split gripping mechanism is described.

Abstract: A sampling system performs an automatic dialysis sampling at specific time intervals of a dialysis treatment. The system includes a fluidic pathway in which a dialysis solution flows, a series of sampling containers, and a valve system. The valve system is arranged in the fluidic pathway. The sampling system includes an electronic system that controls automatically the valve system in order to direct a certain quantity of each fluid sample to a specific sampling container.

Abstract: An actuator for an infusion drive mechanism comprises a piston defining a first axis and being movable within a passageway of the infusion drive mechanism to convey at least one infusion medium. The passageway defines a longitudinal axis. An armature is connected to the piston and defines at least one cavity configured for disposal of a biasing member engageable with a surface of the infusion drive mechanism to orient the first axis transverse relative to the longitudinal axis. Systems and methods of use are disclosed.

Abstract: A set connector assembly for a fluid infusion device is provided. The set connector assembly includes a connector having a body. The body defines a graspable portion and a coupling portion, and the coupling portion is to be received within a portion of the fluid infusion device. The graspable portion has at least one wing that defines at least one locking tab for locking the connector to the fluid infusion device. The graspable portion is movable relative to the body to move the connector between a first, locked position and a second, unlocked position relative to the fluid infusion device.

Abstract: A heated patient tube assembly that carries and gradually warms fluids to a desired temperature and maintains the desired temperature until the fluids are delivered to a patient includes an elongated hollow tube; a heating assembly at least partially embedded within the tube for heating the tube and fluids carried in the tube; and a control assembly for controlling the heating assembly such that the fluids exit the tube at a desired and consistent temperature.

Abstract: This invention provides ambulatory medical systems that include a monitoring device, a therapeutic substance administering device, and a receiver-controller for receiving a signal generated by the monitoring device and controlling the therapeutic substance administering device based on the information received from the monitoring device. The invention also provides methods for using the same.

Abstract: The injection device includes a static structure including a first gear member. The injection device also includes a dynamic structure including a medicine container, a mechanism for pushing liquid medicine out of the medicine container for its injection to a patient, and a second gear member engaged with the first gear member. The injection device additionally includes a drive member for driving one of the first and second gear members so as to cause the dynamic structure to move relative to the static structure along a predetermined direction due to the engagement between the first and second gear members. The injection device further includes a clutch mechanism for maintaining engagement between the first and second gear members in normal condition of the injection device, and for allowing disengagement of the first and second gear members upon a shock received by the injection device along the predetermined direction.

Abstract: Exemplary embodiments provide wearable automatic injection devices for administering a therapeutic agent to a patient's body at fast, controlled rates, for example, in a single fast bolus. Exemplary embodiments also provide methods for assembling wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. Exemplary embodiments also provide methods for using wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates.

Abstract: The invention relates to a self-expandable tube having a catheter body with a double lumen in which one lumen allows for suctioning or decompression and another lumen for a feeding tube. A self-expandable portion collects secretions above the expandable portion or in the anatomical lumen and a suction source coupled to the self-expandable tube removes the secretions as is disclosed herein.

Abstract: Contact lenses are provided for ocular iontophoretic therapy. Implementations include a reservoir adapted to contain a charged therapeutic compound, a current source providing iontophoretic current to the charged therapeutic composition to affect delivery of the charged therapeutic composition into an eyeball, and a sensing circuit controlling the current source to maintain a selected pH range of the charged therapeutic composition. Alternate embodiments include active, sacrificial electrodes for generating ions sufficient to provide electromotive repulsive force to the charged compound to effect transport into ocular tissue.

Abstract: Embodiments of the invention include an introducer for introducing interventional catheters into the vasculature comprising a distal tip, a proximal end, a structural layer, an inner layer, and an outer layer. Other embodiments are also included herein.

Abstract: Methods are disclosed for treating cell components, cells, organelles, organs, and/or tissues with acoustic energy, electromagnetic energy, static or alternating electric fields, and/or static or alternating magnetic fields in the presence or absence of exogenous particulate agents for therapeutic applications.

Abstract: An apparatus includes a cannula assembly, a housing, a fluid reservoir, a flow control mechanism, and an actuator. The housing includes an inlet port removably coupled to the cannula assembly and defines an inner volume. The fluid reservoir is fluidically coupled to the housing and configured to receive and isolate a volume of bodily fluid from a patient. The flow control mechanism is at least partially disposed in the inner volume. The actuator is operably coupled to the flow control mechanism and is configured to move the flow control mechanism between a first configuration, in which bodily fluid can flow, via a fluid flow path defined by the flow control mechanism, from the cannula assembly, through the inlet port and into the fluid reservoir, to a second configuration, in which the fluid reservoir is fluidically isolated from the cannula assembly.

Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the housing having a distal end (D) and a proximal end (P) with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end (P), operate the syringe to supply the dose of medicament (M), and retract the syringe with the needle after delivering the medicament (M). An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.

Abstract: An intradermal injection device comprises a housing, a foot with an opening for passage of a needle; a reservoir movably mounted in the housing, and having a hollow space for holding a fluid; a hollow needle movably mounted in the housing and having a first end for penetrating the subject's skin and a second end for penetrating the reservoir, a plunger movably mounted in the housing for moving the needle through the opening for penetrating the subject's skin, and for pressing the fluid out of the reservoir. The reservoir is frictionally mounted inside the housing by first friction means, and the plunger is frictionally mounted to the reservoir by second friction means. The force to overcome the second friction is larger than the force to overcome the first friction.