Patents Examined by Jean Ellis
  • Asexual blood stage antigens of Plasmodium falciparum which encode a rhoptry protein
    Patent number: 5116755
    Abstract: DNA molecules comprising artificially constructed polynucleotide sequences substantially coresponding to all or a portion of the base sequence coding for an antigen of Plasmodium faliciparum selected from the group consisting of the Acidic Basic Repeat Antigen Rhoptry (ABRA), the antigen of any of clones Ag 169, Ag303, Ag358, Ag361, Ag372, Ag394 or Ag501, defined herein, and other antigens of P. falciparum cross-reactive therewith. Such DNA molecules are capable of being expressed as polypeptide(s). Synthetic peptides or polypeptides displaying the antigenicity of all or a portion of the above antigens of P. falciparum. Compositions for stimulating immune responses against P. falciparum antigens in a mammal, comprising at least one polyupeptide displaying the antigenicity of the above antigens of P. falciparum, together with a pharmaceutically acceptable carrier therefor.
    Type: Grant
    Filed: August 25, 1987
    Date of Patent: May 26, 1992
    Inventors: David J. Kemp, Robin F. Anders, Ross L. Coppel, Graham V. Brown
  • Process for preparing bovine interleukin-2
    Patent number: 5006465
    Abstract: A process for preparing bovine interleukin-2 (bIL-2) by culturing a microbial host transformed by a vector containing a DNA sequence encoding bIL-2 under conditions suitable for the expression of bIL-2 and recovering bIL-2.
    Type: Grant
    Filed: August 11, 1989
    Date of Patent: April 9, 1991
    Inventors: Dirk M. Anderson, Paul E. Baker, Michael A. Cantrell, Douglas P. Cerretti, David J. Cosman, Steven D. Gimpel, Kenneth H. Grabstein, Alf D. Larsen, Kate N. McKereghan