Abstract: A composition for conditioning keratin fibers, comprising: (a) at least one (C10-C30)alkylamido(C1-C8)alkyl(di)(C1-C6)alkylamine and their cosmetic salts and their solvates such as hydrates; (b) at least one dicarboxylic acid containing at least one hydroxyl group, preferably two hydroxyl groups, the said dicarboxylic acid not bearing a cyclic group; (c) at least one oil from eater of C6-C20 fatty acid and C6-C20 fatty alcohol; The composition provides to the keratin fibers, in particular the hair, an improved disentangling, and smoothness sensory.

Abstract: The present invention in the field of hair spray compositions, in particular water-based hair spray compositions. There is a constant need for more environmentally friendly, more sustainable, less harsh and more affordable hair spray products which maintains the current hair spray performance or even provides a superior performance. It is therefore the object of the present invention to provide an environmentally friendly, more sustainable hair spray product providing a long-lasting hold with superior humidity resistance. It has been found that this can be obtained by a water-based aerosol composition comprising a pressure sensitive adhesive.

Abstract: One aspect of the present disclosure relates to a phase transfer cosmetic composition. According to the present disclosure, there can be provided a cosmetic composition which contains a wax having a melting point of 40 to 60° C. and an inulin-based surfactant, wherein the composition maintains a liquid state before applied to the skin and rubbed, and changes to a solid state when applied to the skin, can solve the problems in terms of hygiene and use because it is not used by scooping it by hand, and further, changes its phase to a solid state when applied to the skin and then rubbed, and thus, can solve the problem of dripping when applied to face or skin.

Abstract: Disclosed is a personal care composition comprising: (a) a cationic or nonionic surfactant; (b) a high melting point fatty compound having a melting point of from 25° C. to 60° C. (c) a solid organic compound having a water solubility of lower than 25 g per 1 liter water, and having a melting point of exceeding 60° C., and also having a specific AlogP; (d) a first liquid oily compound other than a second liquid oily compound, wherein the first liquid oily compound has a water solubility of 10 g per 1 liter water or less, wherein a mixture of all the first liquid oily compounds included in the composition has a di-electric constant of from about 5 to about 10, and wherein the weight ratio of the solid organic compound to the first liquid oily compound is from about 1:1 to about 1:10; and (e) an aqueous carrier, wherein the composition comprises 0.1% or less of a second liquid oily compound having a higher AlogP of 7.0 or higher.

Abstract: The present invention provides a method for producing a glyceryl ether-containing composition, the method including: a deodorization step for bringing a glyceryl ether-containing product selected from the group consisting of a monohexyl glyceryl ether-containing product, a monocyclohexyl glyceryl ether-containing product and a mixture thereof into contact with water vapor in an environment having a reduced pressure of 0.10 kPa or more and 10 kPa or less for 60 minutes or more and 600 minutes or less; and an addition step for adding 0.05 to 0.30 parts by mass of an antioxidant containing d-?-tocopherol to 100 parts by mass of the glyceryl ether-containing product, and also provides a glyceryl ether-containing composition containing specific amounts of a specific glyceryl ether and an antioxidant containing d-?-tocopherol.

Abstract: A process for the manufacture of semi-plastic pharmaceutical unit doses using a rotary moulding machine and semi-plastic pharmaceutical dosage units obtained by this process.

Abstract: A cosmetic composition including about 0.01 to about 3 wt. % of retinol; about 0.01 to about 1 wt. % of pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate; about 0.01 to about 3 wt. % of trisodium ethylenediamine disuccinate; about 0.5 to about 7 wt. % of polyglyceryl-3 methylglucose distearate; about 0.9 to about 7 wt. % of sodium polyacrylate; about 0.5 to about 8 wt. % of an oil phase; and water, where all weight percentages are based on the total weight of the cosmetic composition. Additionally, the cosmetic composition is typically formulated to form an oil-in-water emulsion. Methods for treating damaged skin with cosmetic compositions are also disclosed herein.

Abstract: The present invention is directed to a personal care composition comprising from about 12% to about 25% of one or more surfactants; from about 0.01% to 10% of one or more soluble scalp health active; from about 0.1% to about 4% of a thickening polymer wherein the thickening polymer is selected from the group consisting of homopolymers based on acrylic acid, methacrylic acid or other related derivatives, alkali swellable and hydrophobically-modified alkali swellable acrylic copolymers or methacrylate copolymers, soluble crosslinked acrylic polymers, associative polymeric thickeners and mixtures thereof; from 0.01% to 0.8% of a cationic polymer; wherein the personal care composition has a pH of about 4.5 to about 6 and wherein the personal care composition has a Haze value less than or equal to 25.

Abstract: The present invention relates to a composition comprising (a) at least one cationic polysaccharide; (b) at least one crosslinker having three or more acid groups or salt thereof; and (c) at least one physiologically acceptable volatile medium, wherein the composition optionally comprises surfactant(s) in an amount of 1% by weight or less, preferably 0.5% by weight or less, and more preferably 0.3% by weight or less, relative to the total weight of the composition. The composition according to the present invention can provide a self-healing or self-repairing film.

Abstract: The application relates to an emulsifying composition, in particular for cosmetic use, allowing an oil-in-water emulsion (O/W) to be obtained, the emulsion comprising at least one cyclodextrin and at least one O/W emulsifier of natural origin with a hydrophilic-lipophilic balance value (HLB) of more than 8. The O/W emulsifier of natural origin can be selected from alkyl polyglucosides, mixtures of at least one alkyl polyglucoside and at least one fatty alcohol, and non-ethoxylated polyol fatty esters. The application also relates to a composition of the Pickering emulsion type, in particular for cosmetic use, containing the emulsifying composition according to the invention, and to the process for preparing such a composition of the O/W Pickering emulsion type, in particular at low temperatures.

Abstract: Biodegradable contraceptive implants and methods of making and using thereof, are preferably formed of poly(?-pentadecalactone-co-p-dioxanone) [poly(PDL-co-DO)], a family of polyester copolymers that degrade slowly in the presence of water. The material is suitable as the basis of a biodegradable contraceptive implant that provides sustained release of a progestin at a rate similar to a commercially available nondegradable implant. In a preferred embodiment, the progestin is levonorgestrel (LNG), a hormone that prevents pregnancy by preventing the release of an egg from the ovary or by preventing fertilization of the egg by sperm. The implant may be inserted subcutaneously, allowing degradation over a period of up to about 18 or 24 months, eliminating the need for removal by a trained practitioner.

Abstract: The present invention concerns a transdermal therapeutic system, comprising a backing layer, which is not permeable for the active ingredient, and a matrix layer on one side of the backing layer, wherein the matrix layer contains at least one pressure sensitive adhesive and ketamine or a pharmaceutically acceptable salt or solvate thereof, wherein the at least one pressure sensitive adhesive has free hydroxyl groups, as well as its use as medicament, in particular for the treatment of depression and pain.

Abstract: The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxy-phenyl)butan-2-one and a diol compound chosen from 1,3-propanediol, 1,2-octane-diol and 1,2-decanediol, and also to a cosmetic composition containing such a mixture. Use in caring for, making up and cleansing keratin materials.

Abstract: A method of selecting a skin barrier system suitable for infants and young children is disclosed.

Abstract: This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain embodiments, the particles comprise polyelectrolyte polymers, e.g., layers of anionic polymers and cationic polymers. In certain embodiments, the particles have a fibrinogen coating. In certain embodiments, the particles contain a polysaccharide core and/or a polysaccharide coating encapsulating drugs, proteins, clotting agents, coagulation factors, or anticoagulants. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of or duration of bleeding. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of blood clotting.

Abstract: The present invention relates to the use, in a cosmetic, dermatological or pharmaceutical composition, of at least one compound of formula (I): in which: R2 represents a hydrogen atom or a methyl or ethyl radical; R3 represents a linear C1-C12 alkyl radical, optionally substituted with a hydroxyl group; or a linear C2-C12 alkenyl radical, optionally substituted with a hydroxyl group; as a preserving agent. The invention also relates to certain novel compounds and to the cosmetic, dermatological or pharmaceutical compositions comprising them.

Abstract: The present invention relates to the preparation of a membrane for use in the repair of the middle ear including perforations and damage to the tympanic membrane. More particularly, the invention provides for compositions and methods for preparing silk fibroin biocompatible polyurethane membranes using a solvent, which have improved biodegradation, mechanical and vibroacoustic properties.

Abstract: An antimicrobial preservation system comprising: i. itaconic acid or salt thereof and ii. benzoic acid or salt thereof.

Abstract: The present invention provides a combination comprising ciprofloxacin, or a pharmaceutically acceptable salt thereof, and fluocinolone acetonide for use in the prevention and/or treatment of an ocular disease, wherein the prevention and/or treatment comprises the topical administration of the combination. The invention also provides an ophthalmic topical pharmaceutical composition comprising the combination together with at least one ophthalmically acceptable excipient, diluent, or carrier, for use in the prevention and/or treatment of an ocular disease, wherein the prevention and/or treatment comprises the topical administration of the composition.

Abstract: An antimicrobial preservation system comprising: i. itaconic acid or salt thereof and ii. benzoic acid or salt thereof.