Patents Examined by Jennifer Duston
  • Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same
    Patent number: 7393923
    Abstract: Methods using somatic hypermutation (SHM) for producing polypeptide and nucleic acid variants, and nucleic acids encoding such polypeptide variants are disclosed. Such variants may have desired properties. Also disclosed are novel polypeptides, such as improved fluorescent proteins, produced by the novel methods, and nucleic acids, vectors, and host cells comprising such vectors.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: July 1, 2008
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Lei Wang