Abstract: Neurostimulation is performed using electrical AC and/or DC stimulation pulses. Brain and/or spinal cord stimulation of a patient is achieved using an implanted neurostimulation device. Neurostimulation is performed using AC and/or DC stimulation pulses combined with a safe operation in DC mode by discharging build-up loads at the interfaces of the electrodes through short circuiting such stimulation electrodes with a counter electrode, for example a common ground electrode.

Abstract: A physiological signal processing system for a physiological waveform that includes a cardiovascular signal component provides a variable high pass filter that is responsive to the physiological waveform, and that is configured to high pass filter the physiological waveform in response to a corner frequency that is applied. A heart rate metric extractor is responsive to the variable high pass filter and is configured to extract a heart rate metric from the physiological waveform that is high pass filtered. A corner frequency adjuster is responsive to the heart rate metric extractor and is configured to determine the corner frequency that is applied to the variable high pass filter, based on the heart rate metric that was extracted. Analogous methods may also be provided.

Abstract: A biological information analysis device including: an indicator extraction unit configured to extract an indicator indicating a cardiac state, from data regarding blood pressure waveforms that are consecutively measured by a sensor that is configured to be worn on a body part of a user and to be capable of non-invasively measuring a blood pressure waveform for each heartbeat; and a processing unit configured to output the indicator extracted by the indicator extraction unit. The indicator extraction unit is configured to extract a value of a cardiac load indicator for each heartbeat, from the data regarding blood pressure waveforms, and calculate the indicator indicating the cardiac state, based on characteristics related to distribution of values of the cardiac load indicator corresponding to a plurality of heartbeats.

Abstract: One embodiment includes a cardiac ablation system, including an ablation probe including at least one ablation application element to ablate tissue in a chamber of a heart of a living subject, a tracking module to track a position of the at least one ablation application element within the heart, a memory to store a map of the chamber of the heart and store a different, respective default ablation-parameter set for each different region of the chamber, and processing circuitry to segment the map of the chamber into the different regions, receive a user input indicative of commencement of an ablation procedure, identify, responsively to the tracked position, a region of the chamber with which the at least one ablation application element is in contact, retrieve the respective default ablation-parameter set assigned to the identified region, and apply the retrieved default ablation-parameter set in controlling the ablation procedure.

Abstract: Systems and methods for the concurrent treatment of multiple oral diseases and defects while promoting general oral hygiene utilizing electricity are provided for non-human animals. Electrodes are used to deliver an electrical current to the gingival tissues of a mouth in order to achieve a number of therapeutic, prophylactic, and regenerative benefits. These benefits include killing oral microbes, increasing oral vasodilation, reducing oral biofilm, improving oral blood circulation, reversing oral bone resorption, promoting oral osteogenesis, treating gum recession, and fostering gingival regeneration. Other benefits include the treatment of gingivitis, periodontitis, and oral malodor, and other systemic diseases correlated with oral pathogens.

Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Abstract: Methods and devices for managing establishment of a communications link between an external instrument (EI) and an implantable medical device (IMD) are provided. The methods and devices comprise storing, in memory in at least one of the IMD or the EI an advertising schedule defining a pattern for advertisement notices. The advertisement notices are distributed un-evenly and separated by unequal advertisement intervals. The method transmits, from a transmitter in at least one of the IMD or the EI the advertisement notices. The advertisement notices are distributed as defined by the advertising schedule. The method establishes a communication session between the IMD and the EI.

Abstract: An approach is provided that automatically adjusts a band of a wearable electronic device. The approach detects conditions, such as activity-based conditions and location-based conditions, and automatically adjusts the band of the wearable electronic device based on the detected conditions.

Abstract: A wavelength specific photo-modulation treatment device and method are disclosed which provide specific wavelength colors from a group of four different electromagnet colors arranged in a repeating scalable matrix array. The device includes a control system connected to the array for driving the devices in two different modes and three different color combinations.

Abstract: A sealing and/or cutting instrument having a thermally active surface or element which may be used to seal and then cut tissue, ducts, vessels, etc., apart. The instrument may include a thermally active surface or element comprised of a conductor covered with a ferromagnetic material. The instrument may contact tissue with one or more surfaces comprised of a non-stick material. A sensor in communication with the instrument may be used to monitor a therapeutic procedure and signal when sealing and/or cutting of a tissue is complete.

Abstract: Provided herein relates to implantable devices and systems with dynamic silk coatings. In some embodiments, the dynamic silk coatings can be formed in situ or in vivo.

Abstract: The embodiments relate to cardiac assist devices that comprise a jacket that wraps the exterior of the heart, where the jacket comprises one or more pneumatic or hydraulic bladders. The pneumatic or hydraulic bladders are linked to a pump, and the pump fills the bladders with fluid and withdraws the fluid in a cycle to match beats of the heart to assist contraction and pumping of the heart in systole or to assist expansion and filling of the heart in diastole.

Abstract: A method and apparatus for long-term assisting the left ventricle of a heart to pump blood is disclosed which includes at least one transluminally deliverable pump and a transluminally deliverable support structure which secures the at least one pump within the aorta for long-term use.

Abstract: Systems and methods for cardiac fast firing (e.g., atrial fast firing) detection perform frequency analysis on channels of collected cardiac waveform data and test the data for outlier frequency complex content that is of higher frequency than baseline frequency complex content associated with cardiac fibrillation (e.g., atrial fibrillation) or other arrhythmogenic activity. Anatomical regions from whence the cardiac fast firing originates can be displayed in real time on an epicardial surface map via a graphical display, aiding administration of therapy. Prior to such detection, QRST complex removal can be performed to ensure that ventricular activity does not infect the atrial fast firing analysis. A frequency-based method for QRST complex removal is also disclosed.

Abstract: Systems and methods are disclosed for selectively reinforcing or weakening memory associations. At least one current generator provides an electrical current including a plurality of oscillating pulses with at least one predetermined frequency. A user interface includes at least one output device for delivering a sensory stimulus to a user and at least one user input device for registering a response to the stimulus. At least one processor determines from the response, based on at least one predetermined standard, whether an underlying memory association is desired or undesired and respectively sets the at least one predetermined frequency to be a beta or theta frequency. Consequently, the electrical current is generated and administered, via at least one electrode pair, thereby stimulating at least one specific portion of the user's brain so as to reinforce or weaken the underlying memory association.

Abstract: A system is provided for automated monitoring the health of a patient. The system is unifying the approach of multi-sensing, robotic platform and cloud computing to monitor the health of the patient with zero or very minimal human intervention. The plurality of physiological parameters and the pathological values is sensed using the plurality of physiological sensors and the plurality of pathological sensors or using a smart phone of the patient. The body of the patient is scanned using a robotic arm. The data sensed by the sensor is then identifies a set of anomalies and send the set of anomalies to cloud server. A cognitive engine present on the cloud server is then diagnoses a disease using cloud computing and send the report to caregiver and doctor. According to another embodiment, a method is also provided for automated monitoring the health of the person using the above mentioned system.

Abstract: The invention relates to an electromedical implantable or extracorporeally applicable device for treating and monitoring organs as well as a method for therapeutic organ treatment. The aim of the invention is to create an electromedical implantable or externally applicable device which allows healing processes to be excited in diseased organs. Said aim is achieved by an electromedical implantable or extracorporeally applicable device for treating and monitoring organs, comprising a programmable generator and receiver unit which generates and receives electrical microcurrents and electromagnetic power and is connected in a conducting manner to electrodes, a telemetry unit that is integrated into the generator and receiver unit and is provided with a transmitter and a receiver for exchanging data with extracorporeal devices, and a power supply unit.

Abstract: A method of determining an adverse event within a patient having an implantable blood pump including calculating a plurality of power consumption trends of the blood pump during a plurality of time periods using a low-pass filter, determining a plurality of power trend differences between the plurality of power consumption trends, calculating a total amount of the plurality of power trend differences during a time interval, and generating an alarm when the total amount of the plurality of power trend differences exceeds a pre-determined threshold.

Abstract: Disclosed are flexible and stretchable antenna devices, systems and methods of use and manufacture. In some aspects, a flexible and stretchable antenna device includes an adhesive substrate having flexible and stretchable material properties and capable of adhering to a surface of an object; and an antenna attached on or at least partially embedded within the adhesive substrate, the antenna including a radiating element and a ground element, in which one or both of the radiating element and the ground element include a mesh structure allowing the antenna device to transmit or receive wireless communication signals at a predetermined operating frequency while being stretched.

Abstract: Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.