Abstract: A process for selectively controlling or interfering with the effect or function of foreign nucleic acid in the presence of otherwise normal living cells which comprises determining the base sequence for said nucleic acid and binding the said nucleic acid with an appropriately prepared nonionic oligonucleoside alkyl or arylphosphonate analogue which is complementary to the indicated sequence of the foreign nucleic acid.

Abstract: A process is disclosed for producing a 4-O-sulfonyluracil derivative of the formula ##STR1## [wherein R.sup.1 is hydrogen, halogen, alkyl and alkoxy, R.sup.2 is glycosyl having protected hydroxyls; and --SO.sub.2 R.sup.3 is an organic sulfonyl] which comprises reacting an uracil derivative of the formula ##STR2## [wherein R.sup.1 and R.sup.2 are as defined above] with an organic sulfonylating agent of the formula R.sup.3 SO.sub.2 X [wherein R.sup.3 SO.sub.2 is an organic sulfonyl and X is halogen] in the presence of potassium carbonate. The obtained 4-O-sulfonyluracil is further subjected to amination. The processes are industrially adavantageous and produce cytosine derivatives such as cytidine in high yield.

Abstract: 2'-Deoxy-2'-fluoro-.beta.-D-arabinofuranosyl nucleosides of the following structure are disclosed: ##STR1## wherein X and Y are the same or different and are hydrogen, OR.sup.3, SR.sup.3, NR.sup.3 R.sup.4 or NHacyl wherein R.sup.3 and R.sup.4 are the same or different and are hydrogen, lower alkyl of 1 to 7 carbon atoms, aralky, or aryl;NHacyl is alkanoyl or aroylamide;R.sup.1 and R.sup.2 are the same or different and are hydrogen, acyl or aroyl.

Abstract: A compound represented by the formula ##STR1## (wherein X represents a hydrogen atom or a halogen atom) provided in accordance with the invention are novel compounds of value as nonsteroidal antiinflammatory agents. Alpha-tocopherol 5-halouridine phosphoric acid diesters, in particular, are expected to be employable for antitumor agents as well.

Abstract: A novel cyanoimidazole nucleoside and derivative thereof, particularly 4-cyanoimidazolium-5-olate nucleoside and acyl derivatives thereof, and pharmaceutically acceptable salts thereof which are useful as antitumor agents and immunosuppressants, are prepared by dehydrating carboxamide derivatives of the formula: ##STR1## wherein R is an acyl group, and then, if desired, deacylating.