Abstract: A method of treatment of skin tissue with two laser devices of unequal wavelengths comprising the steps of: (1) activating the two laser devices simultaneously to produce two laser beams of unequal wavelength; (2) directing the two laser beams into a handpiece having a distal tip to direct the laser beams onto the skin tissue; (3) directing the two laser beams within the handpiece to an adjustable beam deflector; and, (4) the adjustable beam deflector directing the two laser beams onto the skin tissue to produce a pattern of laser spots simultaneously but separated from one another.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method for vergence matching includes calculating vergence of a wave after refraction on a surface of an IOL and, based on an estimated curvature, converting an initial phase map into a vergence-matched phase map, such that the initial phase map follows the curved vergence of the wavefront.

Abstract: A method of securing an antenna assembly to a wearable article includes positioning a template carrying a first antenna at a desired position on the wearable article worn on a body of a patient. The desired position is in proximity to a wireless tissue stimulator implanted within the body. The method further includes marking a location of the desired position of the template against the wearable article, securing a first attachment feature to the wearable article at a mark located at the desired position, and attaching the antenna assembly to the wearable article at the first attachment feature. The antenna assembly includes a second antenna configured to send a signal carrying electrical energy to the wireless tissue stimulator and a housing carrying the second antenna. The housing includes a second attachment feature configured to engage the first attachment feature for positioning the second antenna adjacent the body.

Abstract: A device for calculating a subject's cardiac pulse transit or arrival time information is configured to receive an electronic audio signal with information indicative of a human voice signal and a primary cardiac pulse signal; generate a power spectral profile of a section of the electronic audio signal, and detect a fundamental frequency (F0) of the generated power spectral profile; generate a denoised audio signal; generate a time-domain intermediate signal that captures frequency, amplitude and/or phase of the denoised audio signal; detect at least one intermediate signal fiducial point, within a human cardiac band, in the intermediate signal; detect at least one primary cardiac pulse fiducial point, within a human cardiac band, in the primary cardiac pulse signal; calculate pulse transit time or pulse arrival time information between the at least one detected primary cardiac signal fiducial point and the at least one detected intermediate signal fiducial point.

Abstract: According to an aspect, there is provided a handheld device (2) for applying energy pulses to skin (17) of a subject to perform a treatment operation as the handheld device is moved across the skin, the handheld device comprising: an aperture (6) that is to be placed adjacent to the skin; at least one energy source (8) for generating an energy pulse and for providing the energy pulse through the aperture to perform the treatment operation on 5 skin adjacent the aperture, wherein the at least one energy source has a minimum pulse repetition period following the generation of an energy pulse before a subsequent energy pulse can be generated; a first skin property sensor (14) for measuring a skin property and for outputting a first measurement signal representing measurements of the skin property at a first sensing position (24), wherein the skin property is a property that changes in response to the application of an energy pulse to the skin, and wherein the first sensing position is in front of the aperture re

Abstract: Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, and delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable.

Abstract: Systems and methods for creating multi-spot laser light beams, multiplexing an illumination light and the multi-spot laser light beams, delivering the multiplexed light to a surgical handpiece via a multi-core optical fiber cable, and delivering the multiplexed light onto patient anatomy.

Abstract: The present invention relates to a laser therapy device and a light transmitting member comprising: a main body provided with a laser light source; a light irradiation unit for irradiating a laser generated in the laser light source to a treatment site; and a light transmitting unit provided between the main body and the light irradiation unit so as to form a path through which the laser is transmitted, wherein the light transmitting unit comprises a plurality of arm members connected by joint parts, and at least one of the plurality of arm members has therein a vacuum forming unit at a position where the laser is focused. According to the present invention, by configuring a compact structure, it is possible to improve the quality of a laser outputted to a treatment site.

Abstract: Multifunctional wireless apparatus, spectrometry instruments, real-time computational system and device ergonomic forms for live and telemetry monitoring of clinical parameters, health data and other vital medical information. Clinical parameters and medical information include pulse rate, respiratory rate, continuous blood glucose levels, continuous blood pressure levels, pulse rate variability, oxygen saturation ratio, body temperature, bio-electrical activity, sleep patterns, sleep health and other vital bio-signal data. The telemetry apparatus encompasses electrical and optical spectrometer instruments. The spectrometer designs and its accompanying circuit design ensure that device is bio-safe, lightweight, low-powered and portable. The bio sensor configuration, comprehensive hardware design, computational process and ergonomic design enables the measurement with more accuracy and efficiency, even in movement artefact prone conditions.

Abstract: A system for electro-therapeutically treating a patient includes a stimulatory device electromagnetically coupled with the nervous system of a patient, an electrical power supply, and a control mechanism structured to energize the stimulatory device by way of the electrical power supply at a stimulation frequency. The control mechanism is further structured to control the energizing so as to produce a treatment signal encoded in the energizing and having a treatment signal frequency equal to or less than the stimulation frequency.

Abstract: An apparatus for tissue regeneration is provided. The apparatus comprises means for generating at least one laser pulse comprising a wavelength; and means for directing the at least one laser pulse onto a tissue surface of a human or animal body, wherein the means for generating comprises control means to ensure that a sum of the pulse energies of the at least one laser pulse is selected so that the corresponding fluence on the tissue surface heats the tissue surface up to a maximal temperature Tmax between 70° C. and a tissue boiling temperature Tb. Further, the means for generating of the apparatus are adapted so that a delivery time ted of the at least one laser pulse (during which the second half of the pulse energy is delivered) is sufficiently short so that, given the wavelength and thus a corresponding penetration depth ? of the at least one laser pulse, a thermal exposure time texp of the tissue surface is shorter than 900 microseconds.

Abstract: A treatment method for non-ablative tissue regeneration includes directing at least one laser pulse having a wavelength onto a tissue surface of a human or animal body, and controlling an energy delivery time ted of the at least one laser pulse, during which the second half of the pulse energy is delivered, to be sufficiently short, so that, given the wavelength and thus a corresponding penetration depth ? of the at least one laser pulse, a thermal exposure time texp of the tissue surface is smaller than 900 microseconds. The thermal exposure time texp of the tissue surface is defined as a time interval in which the temperature of the tissue surface is above To+(Tmax?To)/2, wherein To defines the initial temperature of the tissue surface, before the laser pulse arrives, and Tmax is a maximal temperature of the tissue surface.

Abstract: A method of treatment of skin tissue with two laser devices of unequal wavelengths comprising the steps of: (1) activating the two laser devices simultaneously to produce two laser beams of unequal wavelength; (2) directing the two laser beams into a handpiece having a distal tip to direct the laser beams onto the skin tissue; (3) directing the two laser beams within the handpiece to an adjustable beam deflector; and, (4) the adjustable beam deflector directing the two laser beams onto the skin tissue to produce a pattern of laser spots simultaneously but separated from one another.

Abstract: A light treatment system includes: a probe configured to be inserted into a bladder, the probe including an optical fiber configured to propagate light, and a light emitter that is provided at a distal end of the optical fiber, the light emitter being configured to emit the light; and a balloon catheter into which the probe is inserted, the balloon catheter being configured to be inserted into the bladder, the balloon catheter including a distal end portion that is to be dilated in the bladder, a wall configured to divide inside of the distal end portion into two regions, and a reflector configured to reflect the light emitted by the light emitter, the reflector being provided on a surface of the wall, the surface facing a region of the two regions, the region being where the light emitter is positioned.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method for vergence matching includes calculating vergence of a wave after refraction on a surface of an IOL and, based on an estimated curvature, converting an initial phase map into a vergence-matched phase map, such that the initial phase map follows the curved vergence of the wavefront.

Abstract: An apparatus for measuring a bio-signal includes a pulse wave sensor that may measure a pulse wave signal, of an object of interest, that is non-equidistantly sampled based on a sampling rate of the pulse wave sensor, and a processor that may identify, using a sampling profile, a first interval based on a health index to be measured. The processor may identify, using the sampling profile, a second interval based on the health index to be measured. The processor may set the sampling rate of the pulse wave sensor to a first sampling rate in the first interval. The processor may set the sampling rate of the pulse wave sensor to a second sampling rate, that is less than the first sampling rate, in the second interval.

Abstract: A technique for predicting fluid responsiveness in a critically ill patient comprises measuring physiological data of the patient, then generating an estimate of pulse pressure variability from a Fourier transform of the physiological waveform. Both invasive and non-invasive physiological data measurements may be used.

Abstract: The invention relates to an enhanced method of electrical muscle stimulation.

Abstract: In some examples, a fixation device includes a flexible band with a first base portion, a second base portion, and a connecting strap connecting the first base portion to the second base portion, the connecting strap configured to retain a medical device to an anatomical structure of a patient, wherein the flexible band is constructed of a first material. The fixation device may further include a plurality of inserts, each insert of the plurality of inserts defining an inner channel and constructed of a second material more rigid than the first material of the flexible band, wherein a first insert of the plurality of inserts is at least partially within the first base portion, and wherein a second insert of the plurality of inserts is at least partially within the second base portion.

Abstract: A far ultraviolet light application device for killing pathogens on tissue and proximate thereto includes a tube that is to be utilized in a medical procedure. A first fiberoptic cable is engaged to a wall of the tube so that a first end of the first fiberoptic cable is positioned proximate to a first terminus of the tube. The first fiberoptic cable has a second end operationally engaged an ultraviolet C light emitter so that ultraviolet C light is emitted proximate to the first terminus of the tube. The first fiberoptic cable directs the ultraviolet C light from the ultraviolet C light emitter so that the ultraviolet C light impinges upon tissue and pathogens proximate to the first terminus of the tube to inactivate the pathogens.