Abstract: Compositions, tablets, prills and granules are provided including (a) about 95 to about 99.999 weight percent of at least one alkali metal hydrogen sulfate; and (b) about 0.001 to less than 0.08 weight percent of at least one alkali metal salt of a fatty carboxylic acid and/or at least one alkaline earth metal salt of a fatty carboxylic acid; wherein the composition includes less than 1 weight percent of chlorite and/or hypochlorite and less than 1 weight percent of alkali metal salt and/or alkaline earth metal salt that is chemically different from the at least one alkali metal hydrogen sulfate, the at least one alkali metal salt of a fatty carboxylic acid and the at least one alkaline earth metal salt of a fatty carboxylic acid, on a basis of total weight of the composition. Methods of use also are provided.
Abstract: A subject matter of the present invention is the cosmetic use of at least one compound of formula (I): in which: denotes a divalent radical chosen from a carbon-carbon single bond *—CH2—CH2—* or double bond *—CH—CH—*, of Z or E configuration or their mixtures, b=0 or 1, c=0 or 1, d=0, 1 or 2, and R and R? independently denote a hydrogen atom, a linear C1-C6 alkyl radical or a branched C3-C6 alkyl radical, to treat and/or prevent signs of aging and/or of photoaging of keratinous substances, preferably of the skin, and/or to depigment, lighten and/or whiten keratinous substances, preferably the skin. The present invention also relates to novel compounds and to a corresponding cosmetic method.
Abstract: Silicone gels are described that are adhesive to the skin. The gels are able to be used in particular for articles that are adhesive to the skin for medical or paramedical use.
Abstract: Compositions including at least one Omega-3 fatty acid ester and at least one surface active agent are provided; wherein the compositions form micelles when in contact with an aqueous medium. Also provided is a method of administering to a subject such a composition, wherein the at least one Omega-3 fatty acid ester forms micelles when in contact with an aqueous medium, and the bioavailability of the at least one Omega-3 fatty acid ester is substantially independent of a food effect. The compositions are useful for treating cardiovascular conditions or disorders in a subject and for reducing side effects associated with the ingestion of Omega-3 fatty acid esters. Further provided are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions on how to administer the compositions.
Type:
Grant
Filed:
May 14, 2019
Date of Patent:
June 29, 2021
Assignee:
Omega Biopharma, Inc.
Inventors:
Frederick Sancilio, Peter Persicaner, Janice Cacace, Mohand Dahim
Abstract: The present disclosure relates to a resveratrol delivery system having modified resveratrol composition wherein the active ingredient is stable colloidal resveratrol nanoparticles in unconjugated form. The said composition and its process thereof can be used in numerous applications for treatment of a mammal susceptible to or afflicted with insulin resistance, metabolic syndrome, aging, apoptosis, inflammation, stress resistance, cancer, cardiovascular disease, muscular dystrophy, low fertility rates or any combination thereof since the modified resveratrol composition has higher bioavailability and greater half-life.
Abstract: The invention relates to a cosmetic composition for bleaching the skin, which includes a) at least one oily plant extract from the Glycyrrhiza genus and b) at least one ascorbic acid ester. The invention further relates to the cosmetic, nontherapeutic use of the cosmetic composition according to the invention to treat excessive pigmentation, pigmentation disorders, age spots, and/or post-inflammatory hyperpigmentation of the skin, and to a method for producing a cosmetic skin-bleaching composition in the form of an O/W or a W/O emulsion, wherein an oily extract from licorice roots is dissolved in the water phase by the addition of an ascorbic acid ester.
Type:
Grant
Filed:
December 9, 2016
Date of Patent:
June 8, 2021
Assignee:
Henkel AG & Co. KGaA
Inventors:
Thomas Doering, Natascha Schevardo, Melanie Giesen
Abstract: The present invention concerns palatable veterinary compositions made from one or more pharmaceutical active ingredients having a smell and/or a taste that is repulsive to animals, and a preparation method for preparing said oral veterinary compositions.
Abstract: A method of making a hair care composition is provided, comprising: providing a cationic hair care emulsion, comprising: a cationic surfactant; optionally, a nonionic surfactant; water, wherein the water forms a continuous phase; and an internal phase, wherein the internal phase comprises: a cosmetically acceptable hydrocarbon oil; and a polyolefin blend, comprising: a high density polyolefin having a density of >0.90 g/cm3; and a low density polyolefin having a density of ?0.90 g/cm3; wherein the polyolefin blend has an average melt index of >7 as measured according to ASTM D 1238; providing a cosmetically acceptable silicone; providing an additional water; providing at least one hair care additive; and combining the cationic hair care emulsion, the cosmetically acceptable silicone, the additional water and the at least one hair care additive to form the hair care composition.
Type:
Grant
Filed:
November 30, 2016
Date of Patent:
May 25, 2021
Assignees:
Rohm and Haas Company, Dow Brasil Sudeste Industrial Ltda., Dow Global Technologies LLC
Inventors:
Daisy de Fátima Scarparo de Sanctis, Nikhil J. Fernandes, David L. Malotky, Jodi A. Thomas
Abstract: A UV curable gel composition adapted to be applied to a nail with a brush to build and extend the nail comprising one or more acrylate/carbamate copolymer resins, one or more urethane methacrylate oligomers of di-functionality, one or more methacrylate resins, one or more Isophorone Diisocyanate end-capped with Hydroxyethyl Methacrylate resins, one or more ethylenically unsaturated mono functional monomers, a photoinitiator and at least one acid-based adhesion promotor wherein the composition having a viscosity of about 11,000 centipoise to about 14,000 centipoise and a specific gravity of less than about 1.2. The invention includes an applicator kit for the composition and methods of its use.
Abstract: The present invention relates to a liquid formulation of long-acting insulin conjugate, comprising a pharmaceutically effective amount of a long-acting insulin conjugate, wherein a physiologically active peptide, which is an insulin, is linked to an immunoglobulin Fc region; and an albumin-free stabilizer, wherein the stabilizer comprises a buffer, a sugar alcohol, a non-ionic surfactant, and an isotonic agent, and a method for preparing the formulation. For preventing microbial contamination in multiple uses, a preservative can be added to the formulation. The liquid formulation of the present invention does not comprise a human serum albumin and potentially hazardous factors to body, and thus it has excellent storage stability for insulin conjugate without a risk of viral infection.
Type:
Grant
Filed:
July 25, 2013
Date of Patent:
April 27, 2021
Assignee:
HANMI PHARM. CO., LTD.
Inventors:
Hyung Kyu Lim, Hyun Uk Kim, Sung Hee Hong, Min Young Kim, Sung Min Bae, Se Chang Kwon
Abstract: A starting (raw) material, for cosmetics, comprising a core corona type microgel dispersion obtained by radical polymerization of a specific polyethylene oxide macromonomer, a specific hydrophobic monomer, and a specific cross-linking monomer under specific conditions. The purpose of the present invention is to provide the raw material for cosmetics, with which the cosmetic having a high stability provides a good feeling in use and does not cause skin irritation, can be easily produced.
Abstract: The disclosed invention is directed to an implantable surgical prosthetic mesh having a nanofiber comprising one or more antibiotic and a polysaccharide, and a non-polysaccharide polymer deposited on the mesh. The mesh of the invention is shown to be effective in eliminating or minimizing the bacterial population in the mesh and surrounding tissue for at least 14 days from surgical implantation of the mesh.
Type:
Grant
Filed:
April 28, 2020
Date of Patent:
January 19, 2021
Assignee:
King Abdulaziz University
Inventors:
Abdulmalik Mohammed Saleh Altaf, Seham Alsayed Abdulhady, Faissal Abdel-Hady, Mahmoud Abdul Megead Yassien
Abstract: The present invention relates to compositions and methods for the prophylaxis or treatment of deficiencies in essential amino acid absorption and metabolism and/or of a pathology or symptom associated there with. In particular the invention concerns the treatment and/or prevention of ADHD, ADD and autism spectrum disorders. The present inventors have developed a method for prophylaxis or treatment of such symptoms and/or pathologies associated with a deficiency in essential amino acid absorption and/or metabolism, which method, stated generally, relies on the administration of nicotinamide, typically in a long-acting formulation so as to overcome the deficiencies of existing formulations, which have proven unsuitable for effective treatment.
Type:
Grant
Filed:
September 28, 2017
Date of Patent:
January 5, 2021
Assignee:
APeT Holding B.V.
Inventors:
Hendrik Jan Cornelis Meijerink, Lekhram Changoer, Willem Blom, Marinella Regina Visser, Henderik Willem Frijlink, Anko Cornelus Eissens
Abstract: A composition includes particles of pimobendan with an integral coating of a carrier matrix which serve to ensure a rapid dissolution of the active substance at each pH condition representing the gastrointestinal tract and therefore a reliable absorption, and a method of pimobendan microencapsulation using the spray congealing technology and incorporating the coated particles into oral formulations, for example into tablets.
Abstract: The present invention includes an ultraviolet radiation absorbing polymer composition comprising the polymer compound of formula and compositions containing such an ultraviolet radiation absorbing polymer composition.
Abstract: Provided is a feed for ameliorating weight gain in poultry comprising 25-hydroxy vitamin D, canthaxanthin, Vitamin E and Vitamin C. Animals fed this composition gained weight, but did not become obese, nor did they experience adverse effects associated with hyperphagia related obesity. This feed also provides numerous cardiovascular benefits.
Abstract: The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique.
Type:
Grant
Filed:
November 20, 2019
Date of Patent:
November 24, 2020
Assignee:
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Inventors:
Joseph M. DeSimone, Jason P. Rolland, Benjamin W. Maynor, Larken E. Euliss, Ginger Denison Rothrock, Ansley E. Dennis, Edward T. Samulski, R. Jude Samulski
Abstract: A method for normalizing blood vessels of lesions is disclosed, which includes administering an effective amount of oxygen-loaded microbubbles to a subject in need by intravenous injection, and projecting ultrasound from a ultrasonic emission device into the lesions for rupturing the oxygen-loaded microbubbles and releasing the oxygen to the lesions. Each of the oxygen-loaded microbubbles comprises oxygen and a water insoluble gas, and the particle size of microbubbles is 0.5˜20 ?m.
Abstract: The present disclosure relates to a stabilization mixture, i.e. a finely distributed dispersion of hydrogenated castor oil in water with anionic, amphoteric and nonionic surfactants which is suitable for stabilizing the pearlescence of surfactant agents, particularly cosmetic agents. Furthermore, the present disclosure relates to a cold process for producing surfactant-containing agents having a pearlescent effect, in particular cosmetic cleaning agents having a pearlescent effect, and to the use of the stabilizing mixture for stabilizing surfactant agents containing pearlescent waxes and/or pearlescent pigments containing surfactant agents.
Abstract: The present invention generally relates to topical compositions and methods of using the same. The topical compositions may comprise a hydrophilic composition and a hydrophobic composition in admixture. The hydrophobic composition may include a nitric oxide-releasing compound such as, for example, a diazeniumdiolate functionalized co-condensed silica particle. In some embodiments, the topical composition may be self-emulsifying. Further described herein are kits comprising a hydrophilic composition and a hydrophobic composition.