Abstract: A 2-(benzo[d]thiazol-2-yl)-N?-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)acetimidamide compound, its synthesis, and its use as an antimicrobial agent.
Type:
Grant
Filed:
October 13, 2023
Date of Patent:
April 30, 2024
Assignee:
KING FAISAL UNIVERSITY
Inventors:
Hany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed, Amer A. Amer
Abstract: The present invention relates to sunscreen compositions. More specifically, the present invention relates to sunscreen compositions that, when applied to the skin, prevent sun damage while allowing the passage of sufficient UVB in the range of 290 nm-298 nm to produce vitamin D, while also inhibiting melanogenesis.
Abstract: A pouch designed for administration of an active ingredient in the oral cavity is disclosed, the pouch containing a powder composition having an amount of one or more cannabinoids and a water-insoluble composition including cellulose and/or fibers in the form of particles in an amount of 30 to 80% by weight of the powder composition. The powder composition further includes a water-soluble composition comprising one or more sugar alcohols and the pouch includes a water-permeable membrane. A pouch designed for administration of an active ingredient in the oral cavity is also disclosed.
Abstract: The present disclosure provides solid solution capsule formulations of Compound 1 and methods of making the same. Also provided herein are methods of treating individuals suffering from or susceptible to a disease or disorder involving pathologic activation of C5a receptors by administering an effective amount of one or more solid solution capsules comprising Compound 1. Further provided herein are singe unit dosage capsules comprising certain amounts of Compound 1, and kits comprising a solid solution capsule comprising Compound 1.
Abstract: The invention relates in general to dispersions with a high pigment content, as well as to the uses thereof in the cosmetic industry, and in particular to uses thereof as a makeup composition and particularly as foundation.
Abstract: The present invention relates to a composition, in particular cosmetic, in the form of an oil-in-water emulsion, comprising a continuous aqueous phase and a dispersed oil phase in the form of drops (G1) and drops (G2), wherein the size of the drops (G1) is less than 500 ?m and the size of the drops (G2) is greater than 500 ?m.
Type:
Grant
Filed:
February 10, 2017
Date of Patent:
March 26, 2024
Assignee:
CAPSUM
Inventors:
Mathieu Goutayer, Yan Eric Pafumi, Lucie Chatry, Hélène Balbusquier
Abstract: The present invention relates generally to compositions and methods comprising abiotic, synthetic polymers with affinity and specificity to proteins. The synthetic polymers are an improvement over biological agents by providing a simpler, less expensive, and customizable platform for binding to proteins. In one embodiment, the compositions and methods relate to synthetic polymers with affinity and specificity to vascular endothelial growth factor (VEGF). In one embodiment, the compositions are useful for treating diseases and disorders related to the overexpression of VEGF. In one embodiment, the compositions are useful for treating cancer. In one embodiment, the compositions are useful for detecting VEGF levels from biological samples. In one embodiment, the compositions are useful for detecting overexpression of VEGF from biological samples. In one embodiment, the compositions are used to diagnose cancer.
Type:
Grant
Filed:
September 23, 2022
Date of Patent:
March 26, 2024
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Abstract: A 9-(6-fluoro-2-hydroxyquinolin-3-yl)-10-(2-hydroxyethyl)-3,6-diphenyl-3,4,6,7,9,10-hexhydroacridine-1,8(2H,5H)-dione compound, its synthesis, and its use as an antimicrobial agent.
Type:
Grant
Filed:
November 6, 2023
Date of Patent:
March 26, 2024
Assignee:
KING FAISAL UNIVERSITY
Inventors:
Hany Mohamed Abd El-Lateef Ahmed, Mai Mostafa Khalaf Ali, Antar Ahmed Abdelhamid Ahmed
Abstract: The present invention relates to methods, preferably for controlling and/or preventing infestation of stinkbugs in soybean, comprising applying to a crop of soybean plants, the locus thereof, or propagation material thereof, a compound of formula (I) wherein —B1—B2—B3— is —C?N—O—, —C?N—CH2—, —C?CH2—O— or —N—CH2—CH2—; L is a direct bond or methylene; A1 and A2 are C—H, or one of A1 and A2 is C—H and the other is N; X1 is group X R1 is C1-C4alkyl, C1-C4haloalkyl or C3-C6cycloalkyl; R2 is chlorodifluoromethyl or trifluoromethyl; each R3 is independently bromo, chloro, fluoro or trifluoromethyl; R4 is hydrogen, halogen, methyl, halomethyl or cyano; R5 is hydrogen; or R4 and R5 together form a bridging 1,3-butadiene group; p is 2 or 3.
Abstract: The present invention relates to microparticles comprising moxidectin and a biodegradable polymer, wherein the microparticles comprising moxidectin have a shape allowing a moxidectin drug to be uniformly distributed in spherical biodegradable polymer particles, and the average particle diameter of the microparticles is 80-130 ?m. The present invention relates to: extended release microparticles capable of continuously maintaining a heartworm disease prevention effect for 3 months to 6 months by administering microparticles comprising moxidectin; and a preparation method therefor. In addition, the present invention is prepared such that the average diameters of the particles have a predetermined micrometer size, and thus reduces a foreign body sensation and pain during administration into an animal through injection, thereby enabling administration through injection to be facilitated.
Abstract: The present invention relates to compositions and methods for malodor reduction. The malodor control compositions are suitable for use in a variety of applications, including use in consumer products, for example, air freshening compositions, laundry detergents, fabric enhancers, surface cleaners, beauty care products, dish care products, diapers, feminine protection articles, animal and pet litter compositions and plastic films for garbage bags. Such malodor control technologies do not unduly interfere with the scent of the perfumed or unperfumed situs that is treated with the malodor control technology.
Type:
Grant
Filed:
November 20, 2017
Date of Patent:
March 12, 2024
Assignee:
Bell Flavors & Fragrances, Inc.
Inventors:
Marvel Fields, Richard Nero, Steve Orson, Robert Siegel, John Kocis
Abstract: The present disclosure relates to a foodstuff composition, in particular a spreadable food composition, more in particular an olive oil-based functional spread fat composed by olive oil fortified with a functional ingredient—the olive pomace active ingredient. This functional ingredient is a mixture of bioactive compounds, in particular hydroxytyrosol, tyrosol, sterols, tocopherols, triterpenes, coenzyme Q10, K, Mg and Ca, among others, obtained from olive pomace by mechanical pressing.
Type:
Grant
Filed:
December 14, 2018
Date of Patent:
March 5, 2024
Assignee:
UNIVERSIDADE DO PORTO
Inventors:
Maria Beatriz Prior Pinto Oliveira, Maria Antónia Da Mota Nunes, Anabela Sílvia Guedes Da Costa
Abstract: A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
Type:
Grant
Filed:
January 6, 2023
Date of Patent:
February 27, 2024
Inventors:
Matthias Rath, Vadim Ivanov, Aleksandra Niedzwiecki
Abstract: An aqueous solution for intraoral cleaning via irradiation with ultraviolet ray and/or near-ultraviolet visible ray and/or ray in an 800-900 nm near-infrared region is employed as the hydrogen peroxide aqueous solution, wherein a concentration of hydrogen peroxide is 1 w/v % to 7 w/v %, and a concentration of a hydrogen peroxide stabilizer is 81 ppm (mg/L) or less in the aqueous solution.
Abstract: An aqueous solution for intraoral cleaning via irradiation with ultraviolet ray and/or near-ultraviolet visible ray and/or ray in an 800-900 nm near-infrared region is employed as the hydrogen peroxide aqueous solution, wherein a concentration of hydrogen peroxide is 1 w/v % to 7 w/v %, and a concentration of a hydrogen peroxide stabilizer is 81 ppm (mg/L) or less in the aqueous solution.
Abstract: The present disclosure provides a patch preparation having features that prevent accidental use. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the patch is removed from the skin. This feature prevent the used patch from being applied to the skin again, and can prevent accidental use. A method of forming a patch preparation is also disclosed.
Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction. In particular, the present invention relates to a method of treating post-operative cognitive dysfunction in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an APJ receptor agonist.
Type:
Grant
Filed:
September 27, 2022
Date of Patent:
February 13, 2024
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
Inventors:
Philippe Valet, Cedric Dray, Vincent Minville, Bernard Frances, Francois Labaste, Claire Vinel
Abstract: Provided herein are compositions comprising nicotine, or a salt thereof, and pilocarpine, or a salt thereof, useful for reducing the use of betel quid and/or achieving betel quid cessation (e.g., replacement therapy). Also provided herein are methods of using the compositions in reducing the risk of developing or reducing the progression of a disease (e.g., cancer, oral disease, neurological disease, or painful condition). Compositions of the present invention may be administered to a subject with an addiction, e.g., a betel quid addiction, areca nut addiction, and/or nicotine addiction.
Type:
Grant
Filed:
January 17, 2019
Date of Patent:
February 6, 2024
Assignee:
University of Florida Research Foundation, Incorporated
Abstract: A nutritional supplement provides Vitamin E; Sophora flavescens extract; zinc sulfate; and a remainder of at least one of the following ingredients: grape seed extract; boswellia extract; micronized Resveratrol; Vitamin B6; black pepper; magnolia powder; poplar powder; willow bark powder; methyl sulfano methane; chia; Vitamin C; Pine powder; Curcumin; Oregano; Ginger; Orange peel; and Meadow sweet. The supplement can be used to reduce joint inflammation, reduce stiffness, reduce lameness, improve flexion, and improve amount of movement and mobility by supporting joint health.