Abstract: A method is provided for authenticating a botanical. The method includes identifying at least one marker compound of the botanical. A sample comprising the botanical is injected into a chromatography system that includes a mobile phase delivery module, an autosampler, a chromatography column, a chromatography column manager, and at least one detector. The method also includes extracting a chromatogram of the at least one marker compound and extracting a spectrum at a chromatographic peak retention time of the at least one marker compound. The method also includes quantifying at least one peak of the extracted chromatogram and quantifying at least one band of the extracted spectrum. The quantified at least one peak of the extracted chromatogram and the quantified at least one band of the extracted spectrum are compared to a set of authentication criteria to determine authenticity of the botanical.

Abstract: An example method includes providing fluid to a chamber. The chamber feeds a first channel terminating at a first droplet ejector and a second channel terminating at a second droplet ejector. The method further includes sequencing ejection of droplets at the first droplet ejector and the second droplet ejector to induce negative pressure to provide a sequenced output flow of the fluid through the first channel to a first target microfluidic network and through the second channel to a second target microfluidic network, and controlling the first and second target microfluidic networks to perform an analytical process with the fluid.

Abstract: Methods and apparatus for manufacturing a microfluidic arrangement are disclosed. In one arrangement, a continuous body of a first liquid is provided in direct contact with a first substrate. A second liquid covers the first liquid. A separation fluid, immiscible with the first liquid, is propelled through at least the first liquid and into contact with the first substrate along all of a selected path on the surface of the first substrate. First liquid that was initially in contact with all of the selected path is displaced away from the selected path. The first liquid is divided to form sub-bodies of first liquid that are separated from each other. For each of one or more of the sub-bodies, a sub-body footprint represents an area of contact between the sub-body and the first substrate, and all of a boundary of the sub-body footprint is in contact with a closed loop of the selected path surrounding the sub-body footprint.

Abstract: Micro-valve system includes two or more superimposed tubes and a pressing device for fluid control in miniaturized capillary connections. The micro-valve system and method of fabrication can be tailored to the requirements of a wide range of applications; composition, sturdiness and thickness of plastic tubes; and capable of been adapted to the resilient of mechanical pressure and the passing and transport of fluid types.

Abstract: A method of analyzing a metal component contained as an impurity in a polymer composition that contains a polymer and an organic solvent including a step (i) of preparing a dispersion by mixing the polymer composition with an acid aqueous solution, a step (ii) of separating the dispersion prepared in the step (i) into a dispersoid layer containing the polymer and a dispersion medium layer containing the metal component, and a step (iii) of quantifying the metal component contained in the dispersion medium layer separated in the step (ii).

Abstract: An automatic sample injection device includes: an; and a management device. The injector includes: a turret; and a vial sensor. The management device includes: a condition setting unit configured to set a condition relating to a type of a vial to be used in the sample injection operation, based on information input by a user; and a vial determination unit configured to determine, before the injector initiates the sample injection operation, whether or not there is a missing vial on the turret out of the vials of the plurality of types set to be used in the sample injection operation under a condition set by the condition setting unit, by using a detection result of the vial sensor.

Abstract: Disclosed is a calibration curve creation method performed by an analyzer, the calibration curve creation method including: preparing a plurality of calibrators at different dilution rates by dispensing a calibrator in a container into one or more different containers; obtaining a plurality of measurement values by measuring each of the prepared plurality of calibrators; creating a calibration curve by use of the plurality of measurement values; selecting a first measurement value to be re-measured, among the plurality of measurement values used for the calibration curve; preparing another calibrator at a dilution rate corresponding to a calibrator from which the selected first measurement value is obtained; obtaining a second measurement value by measuring the prepared another calibrator; and creating a new calibration curve by replacing the first measurement value, among the plurality of measurement values, with the second measurement value.

Abstract: A fluidic bridge device for transport of a fluid sample between a first sample processing device and a second sample processing device. The fluidic bridge may include one or more fluid channels extending between fluid-tight couplings attachable to transfer ports of the first and second sample processing device. In one aspect the first device is a sample preparation device and the second device is an assay device. The fluidic bridge can include at least two fluid conduits, at least one for transport of the prepared sample, and at least one other to facilitate displacement of air to allow flow of the prepared sample through the other fluid conduit. The fluid channels can include one or more of an amplification chamber, a processing chamber, a gas-permeable vent, a bubble trap, a filter, and an external port. Methods of preparing and transporting a fluid sample between devices are provided herein.

Abstract: The extraction system according to the invention for extracting analytes from a sample comprises an extraction cell for receiving the sample, which has at least one first fluid connector for the supply or discharge of a fluid, and a clamping device for clamping the extraction cell, and a fluid connection device for establishing a fluid connection with the at least one first fluid connector of the extraction cell, wherein an extraction cell holder is provided for receiving the extraction cell, and the clamping device has a guiding and positioning arrangement for linearly inserting the extraction cell holder, together with the extraction cell, in order to position the extraction cell in an insertion position.

Abstract: A compact rock pyrolytic analysis and evaluation instrument comprises a sample introduction system, a pyrolytic furnace, a bypass system, a total hydrocarbon amount and methane content analysis system, a signal acquisition control system and a computer. The pyrolytic furnace is respectively connected with the sample introduction system and the bypass system, the total hydrocarbon amount and methane content analysis system is connected with the bypass system, the signal acquisition control system is used for controlling and connecting the total hydrocarbon amount and methane content analysis system, and meanwhile, the signal acquisition control system is communicated with the computer. The disclosure simultaneously detects the total amount of hydrocarbons produced by rock pyrolysis and the content of methane gas produced by rock pyrolysis, and the obtained data are reliable.

Abstract: A combinable cavity tray for liquid handling is provided. The combinable cavity tray has at least one cavity for receiving a fluid and at least one passage for leading through a cavity of a second combinable cavity tray and/or for connecting to a pipetting apparatus. The at least one cavity of the combinable cavity tray is formed integrally. An assembly of combinable cavity trays having at least two combinable cavity trays, a method of manufacturing a combinable cavity tray and the use of a combinable cavity tray or of an assembly of combinable cavity trays for liquid handling are provided.

Abstract: A sampling device comprises a receptacle having an inner material receiving space defined by a side wall portion and a bottom wall portion and having a receptacle opening; and a sample container being adapted to close the receptacle opening when collocated with the receptacle. The sample container includes: a sample receiving portion which, when collocated with the receptacle is located in liquid communication with the inner material receiving space; a sample well positioned radially outside of the sample receiving portion in a direction perpendicular to a longitudinal axis, the sample well having a well opening; a liquid passageway for directing liquid from the sample receiving portion towards the well opening; a container having a container opening; and a liquid impermeable barrier for preventing liquid entering the container opening from the sample receiving portion).

Abstract: The invention, in part, includes methods of single molecule protein sequencing that include using weak binding spectra in the amino acid identification.

Abstract: A centrifuge tube, a detection system and a detection method. The centrifuge tube includes: a tube body comprising an inner surface and an outer surface, a sensor provided at the inner surface of the tube body and comprising a first electrode group; and a second electrode group provided at the outer surface of the tube body and electrically connected with the first electrode group.

Abstract: Disclosed herein are methods of analyzing a biological sample comprising: separating components of the biological sample via reversed-phase (RP) chromatography to obtain an elute; subjecting the elute to separation via ion-exchange (IEX) chromatography or mixed-mode IEX chromatography; and detecting the separated compounds to determine the components of the biological sample. Also disclosed are devices comprising a reversed-phase (RP) chromatography column in communication with an ion-exchange (IEX) chromatography column or mixed-mode IEX chromatography column, wherein there is no switching valve between the columns.

Abstract: Provided is an automated analyzer comprising a temperature regulator that can be made more compact in size while maintaining high-precision temperature regulation. In a temperature-regulating unit (20) of the automated analyzer, a first chemical reservoir (1) is constituted by a large-diameter spiral-shaped pipe, and a second chemical reservoir (2) is constituted by a large-diameter chemical reservoir container. The first chemical reservoir (1), which is positioned upstream of the second chemical reservoir (2), has an internal capacity that is set so as to be greater than the volume of a single discharge of each of syringe pumps (29, 30, 31), and the second chemical reservoir (2) also has an internal capacity (volume) that is set so as to be greater than the volume of a single discharge of each of the respective syringe pumps (29, 30, 31).

Abstract: A container includes a lower portion and a lid to connect with the lower portion. The lid includes a fluidic interface, a swing bar, and a counter structure disposed on an opposite side of the fluidic interface relative to the swing bar. The fluidic interface includes a first liquid port, a second liquid port, a gas port, and a seal ring disposed around the first liquid port, the second liquid port, and the gas port, the first liquid port disposed along a center axis of the container.

Abstract: Provided herein is a method for authenticating animal hide gelatins using peptide markers found animal hide gelatin hydrolysates. The method can be used to authenticate animal hide gelatins derived from donkey hide, horse hide, pig hide, and cattle hide.

Abstract: Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceuti

Abstract: The invention having functional vertical disposable reaction systems having a vertically mounted semipermeable membrane for sample preparation, chemical reactions, dialysis, enzymatic/microbiological fermentation, multistage processes, in vitro protein biosynthesis on a laboratory scale, formed from a base body and an exchangeable lid having different functions. For exchange across the membrane, the system is placed vertically into an outer volume consisting of gas, liquid or solid constituents. The system consists of a dimensionally stable base body and a liquid-tight lid having a functional support going toward the base of the base body, the dimensionally stable base body forming at least one noncapillary reaction space as inner volume with at least one semipermeable membrane as lateral wall. The high flexibility in use results from the combination of variants of the base bodies with different lid variants for different areas of use.