Patents Examined by John Kim
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Patent number: 11969530Abstract: A system and a solution-preparation-determining apparatus which determines whether additional preparation of an undiluted dialysate solution is necessary.Type: GrantFiled: November 9, 2021Date of Patent: April 30, 2024Assignee: Nikkiso Company LimitedInventors: Shunsuke Taguchi, Ryouhei Matsumoto, Yutaka Ishikawa, Takeshi Ichikawa
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Patent number: 11969534Abstract: Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized.Type: GrantFiled: May 5, 2023Date of Patent: April 30, 2024Assignee: NxStage Medical, Inc.Inventors: James M. Brugger, David Desouza
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Patent number: 11964266Abstract: A process for removing Co2+, Pb2+, Cd2+ and Cr3+ toxins from bodily fluids is disclosed. The process involves contacting the bodily fluid with an ion exchange composition to remove the metal toxins in the bodily fluid, including blood and gastrointestinal fluid. Alternatively, blood can be contacted with a dialysis solution which is then contacted with the ion exchange composition. The ion exchange compositions are represented by the following empirical formula: AmZraTibSncMdSixOy. A composition comprising the above ion exchange compositions in combination with bodily fluids or dialysis solution is also disclosed. The ion exchange compositions may be supported by porous networks of biocompatible polymers such as carbohydrates or proteins.Type: GrantFiled: July 9, 2019Date of Patent: April 23, 2024Assignee: UOP LLCInventors: Gregory John Lewis, Paulina Jakubczak, Julio C. Marte, William Christopher Sheets
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Patent number: 11957825Abstract: A column is disclosed for removal of sTNF-R2 from a body fluid. The column has a compartment, an inlet coupled to the compartment and configured to receive the body fluid, and a substrate disposed within the compartment. A capture ligand is coupled to the substrate and has a modified sequence with an amino acid substitution in a reference sequence that includes a portion of a natural TNF sequence. The modified sequence has an affinity for the sTNF-R2 that is greater than an affinity of the reference sequence for the sTNF-R2.Type: GrantFiled: June 17, 2022Date of Patent: April 16, 2024Assignee: IMMUNICOM INC.Inventors: Michael Matho, Steven F. Josephs, Annette Marleau
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Patent number: 11957823Abstract: An automated peritoneal dialysis (APD) device, system and method is provided, which utilizes mechanisms to admix customized dialysate solutions from multiple sources, while maximizing volumetric accuracy. The present automated peritoneal dialysis (APD) device can accomplish these goals all within the convenience and comfort of the patient's home utilizing filtered tap water.Type: GrantFiled: August 10, 2020Date of Patent: April 16, 2024Assignee: Simergent LLCInventors: Steve J. Lindo, Richard A. Pendergraft, Jacob Henderson, Erika Mallery, Alexandra Arment
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Patent number: 11957824Abstract: Hemofilters for in vivo filtration of blood are disclosed. The hemofilters disclosed herein provide an optimal flow of blood through the filtration channels while maintaining a pressure gradient across the filtration channel walls to enhance filtration and minimize turbulence and stagnation of blood in the hemofilter.Type: GrantFiled: November 14, 2022Date of Patent: April 16, 2024Assignees: The Regents of the University of California, Vanderbilt UniversityInventors: Shuvo Roy, William Fissell, Nathan Wright, Mark Goodin, Steven G. Goebel, Amanda Buck, Joey Groszek
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Patent number: 11951244Abstract: A fluid temperature control device for an extracorporeal blood treatment apparatus, comprises: a casing (26) delimiting a heating/cooling seat (20) configured to accommodate a fluid warming bag (17) connected or connectable to an extracorporeal blood treatment apparatus (1); heating elements (29, 30) operatively active in the heating seat (20) to heat the fluid warming bag (17); at least a presence detector (32, 33) operatively active in the heating seat (20) to detect the presence of the fluid warming bag (17). The presence detector (32, 33) comprises an electromagnetic transmitter (34) and an electromagnetic receiver (35).Type: GrantFiled: May 10, 2019Date of Patent: April 9, 2024Assignee: Gambro Lundia ABInventor: Michael Jon Wangen
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Patent number: 11951241Abstract: Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.Type: GrantFiled: November 28, 2022Date of Patent: April 9, 2024Assignee: Outset Medical, Inc.Inventors: James Ritson, Michael Edward Hogard, Gopi K. Lingam, Shih-Paul Chen, Dean Hu
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Patent number: 11951243Abstract: Systems, methods, and/or apparatuses may be operative to perform a dialysis process that includes a displacer infusion process. The dialysis machine may include at least one processor and a memory coupled to the at least one processor, the memory comprising instructions that, when executed by the processor, may cause the at least one processor to access dialysis information for a dialysis process performed by a dialysis machine, the dialysis information indicating a target substance to be displaced from a binding compound by a displacer, and determine an infusion profile for infusing the displacer into a patient during a displacer infusion process of the dialysis process, the infusion profile determined based on the dialysis information and an infusion constraint. Other embodiments are described.Type: GrantFiled: September 13, 2022Date of Patent: April 9, 2024Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Vaibhav Maheshwari, Peter Kotanko
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Patent number: 11944735Abstract: A device for separating blood plasma from whole blood includes a first reservoir and a second reservoir. The first reservoir is configured to receive a sample of whole blood including red blood cells and includes a collection region and a constricted region. The second reservoir is fluidically connected to the constricted region of the first reservoir, such that, responsive to centrifugal force applied to the device, the sample of whole blood disposed within the first reservoir separates into a first fraction and a second fraction. The first fraction is located in the collection region and includes blood plasma from which substantially all red blood cells have been removed. The second fraction is located in the second reservoir and includes blood plasma and red blood cells that have been removed from the first fraction by the centrifugal force. The constricted region inhibits the second fraction from entering the collection region.Type: GrantFiled: April 4, 2023Date of Patent: April 2, 2024Assignee: Truvian Sciences, Inc.Inventors: Ian Kleinemolen, Dena Marrinucci, Kameel Michael Abi-Samra
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Patent number: 11938255Abstract: The present invention is to provide a means capable of properly balancing water and sodium in peritoneal dialysis treatment, without causing hyponatremia, while avoiding adversely affecting residual renal function. A peritoneal dialysate containing 1.5 to 1.8 w/v % of glucose and 120 to 130 mEq/L of sodium, and being for independent use once or twice a day, wherein the peritoneal dialysate is used in combination with another peritoneal dialysate that contains 1.35 to 2.5 w/v % of glucose and 132 to 135 mEq/L of sodium, in peritoneal dialysis that involves injection of an amount of 1.5 to 2.0 L per one time in an abdominal cavity of a subject, storage and drainage three to five times a day.Type: GrantFiled: February 27, 2019Date of Patent: March 26, 2024Assignee: TERUMO KABUSHIKI KAISHAInventor: Hiroaki Takahashi
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Patent number: 11931500Abstract: A pressure detector that includes a case connectable to a flow route for liquid, and a membrane member provided in the case and with which a liquid-phase portion to be supplied with the liquid in the flow route and a gas-phase portion to be supplied with gas are separated from each other, the membrane member being displaceable in accordance with a pressure of the liquid supplied to the liquid-phase portion, the pressure detector detecting the pressure of the liquid in the flow route by detecting a pressure in the gas-phase portion. The gas-phase portion has an opening through which the gas is allowed to be introduced or discharged in accordance with the displacement of the membrane member, and a secured portion secured for the introduction or discharge of the gas through the opening during the displacement of the membrane member toward a side of the gas-phase portion.Type: GrantFiled: November 10, 2020Date of Patent: March 19, 2024Assignee: Nikkiso Company LimitedInventors: Hiroyuki Kawajiri, Shingo Okamoto, Ryo Kato
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Patent number: 11925739Abstract: An implantable or wearable kidney enclosure that is cylindrical, ovoid, or otherwise non-angular e.g., not rectangular or cuboid), having a circular or oval hemofilter that provides a blood flow pattern from an internal, central artery source radially outwards. Due to the efficient flow of the circular filter design, the enclosure can be made in a cylindrical low profile shape, resulting in a compact enclosure highly suitable for implantable and wearable dialysis applications.Type: GrantFiled: October 21, 2020Date of Patent: March 12, 2024Assignee: SEAGATE TECHNOLOGY LLCInventor: Thomas Y. Chang
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Patent number: 11918955Abstract: Disclosed are apparatus and methods for blood and other biological fluid purification using a membrane with cell containing vascular channel systems and filtration channel systems. Also disclosed are methods of making the apparatus as well as methods of making membranes.Type: GrantFiled: August 15, 2022Date of Patent: March 5, 2024Assignee: IVIVA Medical, Inc.Inventors: Charles C. Klassen, Harald C. Ott, Maria Jaramillo, Robert G. Hesse, Daniel Cheng
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Patent number: 11911554Abstract: A method and automated system for processing blood in which the automated system includes a programmable controller, a database, and an interactive display screen for displaying information and receiving operator input. The programmable controller is configured to automatically control the system to perform the method. Upon activation of the system, the screen displays a listing of different blood processing procedures that may be performed using the system. The operator may then input into the controller an identification of a specified blood processing procedure that is to be performed, such that an initial list of parameters that are associated with the specified blood processing procedure are displayed on the screen. The operator may then input into the controller an identification of the parameters that are to populate the display screen during performance of the procedure and indicate a format in which the selected parameters are to be presented on the display screen.Type: GrantFiled: June 13, 2022Date of Patent: February 27, 2024Assignee: Fenwal, Inc.Inventor: Matthew J. Schoonover
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Patent number: 11911549Abstract: Apparatus for treating blood. A device (10) for separating plasma from blood comprises a blood flow path (20) including formations (24) for agitating blood flow along the blood flow path and a separation membrane (28) with a first surface in fluid communication with the blood flow path. The device may be comprised in an extracorporeal blood circuit and used in a method for separating plasma from blood.Type: GrantFiled: March 12, 2019Date of Patent: February 27, 2024Assignee: TSI TECHNOLOGY LIMITEDInventors: Stephen Cotton, Terence Gourlay
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Patent number: 11911551Abstract: Methods and devices are disclosed for the treatment of a subject suffering from drug intoxication by cleansing a contaminated sample from the subject with adsorption media. The adsorption media composition is selected for its antithrombogenic properties and for its ability to adhere to one or more drug targets to be reduced or eliminated. The media can further be held in a cartridge for use in extracorporeal treatments such as those of hemoperfusion. Contacting the contaminated sample from the subject with the absorption medium allows for the separation of a portion of the drug target from the sample, producing a cleansed sample that can be infused into the subject.Type: GrantFiled: August 28, 2020Date of Patent: February 27, 2024Assignee: ExThera Medical CorporationInventors: Robert S. Ward, Keith R. McCrea
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Patent number: 11911544Abstract: A blood purification apparatus that includes a blood circuit including an arterial blood circuit and a venous blood circuit and that allows a patient's blood to extracorporeally circulate, with a blood purifier that is interposed between the arterial blood circuit and the venous blood circuit and purifies; a dialysate temporary chamber that temporarily stores dialysate received from a dialysate storage supported by a supporting unit; a substitution-fluid temporary chamber that temporarily stores substitution fluid received from a substitution-fluid storage supported by the supporting unit; a first dialysate introduction line through which the dialysate in the dialysate storage flows into the dialysate temporary chamber; and a substitution line through which the substitution fluid in the substitution-fluid storage flows into the substitution-fluid temporary chamber.Type: GrantFiled: April 8, 2021Date of Patent: February 27, 2024Assignee: Nikkiso Company LimitedInventors: Tomohiro Furuhashi, Yuki Eda, Masaaki Ohta, Kenji Furuhashi
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Patent number: 11911546Abstract: A method of performing dialysis includes: recirculating a dialysis fluid from a patient or a dialyzer for at least two cycles, each cycle contacting the dialysis fluid first with a zirconium phosphate layer followed by at least one of a urease layer, a zirconium oxide layer, or a carbon layer; storing the recirculated dialysis fluid in a storage container; and transferring the dialysis fluid from the storage container to the patient or the dialyzer. In one example, the zirconium phosphate layer and the at least one of the urease layer, the zirconium oxide layer, or the carbon layer is provided by a sorbent cartridge.Type: GrantFiled: January 7, 2022Date of Patent: February 27, 2024Assignees: Baxter International Inc., Baxter Healthcare SAInventor: Sujatha Karoor
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Patent number: 11908563Abstract: A machine for extracorporeal blood treatment includes a user interface having a touch screen and a controller programmed to display on a screen (16) a display in which two distinct areas are arranged, one of which (161) exhibits a series of touch keys (17), wherein activation of any one touch key (17) causes visualization of an image in a second area (162) of the screen, wherein the images are displayed alternatively and are at least partly different one from another, wherein each touch key (17) is associated to an instruction, or to a group of instructions, each concerned with readying the machine for use, wherein each image is a pictograph of a configuration of the machine, correlated with an instruction associated to the touch key (17) selected, and wherein the operator is aided in making the machine ready for treatment.Type: GrantFiled: October 5, 2020Date of Patent: February 20, 2024Assignee: Gambro Lundia ABInventors: Massimo Zaccarelli, Lorenza Ferrarini, Danielle Pelletier, Jeffrey J. Letteri