Abstract: In some embodiments, without limitation, the invention comprises a catheter having an elongated housing with a channel disposed therein. A laser delivery member is movable and at least partially disposed within the channel. A ramp is disposed within the housing at an angle to its central axis and proximate to its distal end. The ramp is adapted to move the distal end of the laser delivery member outwardly from the central axis of the housing. A guidewire biases the distal end of the laser delivery member generally inwardly toward the central axis of the housing. In some embodiments, without limitation, the offset of the central axis of the tip of the laser delivery member from the central axis of the housing is determined by adjusting the extent to which the laser delivery member travels on the ramp, and disposition of the laser delivery member on the guidewire maintains the offset tip substantially parallel to the central axis of the housing.

Abstract: The various embodiments disclosed herein relate to modular medical devices, including various devices with detachable modular components and various devices with pivotally attached modular components. Additional embodiments relate to procedures in which various of the devices are used cooperatively. Certain embodiments of the medical devices are robotic in vivo devices.

Abstract: A surgical tool having an electromagnetic (EM) sensor component is provided. The surgical tool has a flexible shaft portion. Additionally, the surgical tool has a rigid portion attached to the flexible shaft portion. The rigid portion comprises at least one EM sensor within the rigid portion. The at least one EM sensor comprises an extended core portion surrounded by a coil. Additionally, the at least one EM sensor generates a change in voltage when exposed to an electromagnetic field.

Abstract: Disclosed herein are systems and methods involving the use of magnetic resonance imaging and optogenetic neural stimulation. Aspects of the disclosure include modifying a target neural cell population in a first region of a brain to express light-responsive molecules. Using a light pulse, the light-responsive molecules in the target neural cell population are stimulated. Multiple regions of the brain are scanned via magnetic resonance imaging. The scans allow for observation of a neural reaction in response to the stimulation in at least one of the multiple regions of the brain.

Abstract: An ophthalmic system may comprise an imaging device having a field of view oriented toward the eye of the patient; a patient interface housing defining a passage therethrough, having a distal end coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to the patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that they may be imaged by the imaging device in reference to predetermined geometric markers on the eye of the patient which may also be imaged by the imaging device.

Abstract: A scanning mechanism to scan a light source, such as a low-level laser, to create a desirable energy distribution on a treatment area. The light source may include multiple light beam generators, each having a different wavelength and each having a different energy distribution. The scanning mechanism can be programmable to scan in different patterns in accordance with a desired treatment.

Abstract: A computer-implemented method and system of hardware for acquiring objective data relating to biometric and physiological parameters of an individual to diagnose, devise a treatment plan, and/or monitor an emotional and mental state of the individual. The method and system are designed to capture and process in real time clinical observations of patient responses and reactions in different clinical and patient settings and situations.

Abstract: A fixation mechanism (5) fixes a flex coil unit of a MRI system onto a patient. An oblique-shaped clip (9) includes a first portion (9a) and a second portion (9b) arranged to form an oblique angle therebetween. The first portion (9a) is configured to be arranged with a strap (7) along which the oblique-shaped clip (9) is subject to a force when the flex coil unit is fixed onto the patient. An elongated slot (11) is located at a longitudinal side of a housing of a spine coil unit of the MRI system and formed at least partially by the housing of the spine coil unit. The elongated slot (11) is configured to receive the second portion (9b) of the oblique-shaped clip (9) and further configured to allow the second portion (9b) of the oblique-shaped clip (9) to abut against a side wall of the elongated slot (11) by the force along the strap (7). An operator conveniently inserts the clip into the slot or release the clip out of the slot at any position along the longitudinal direction of the housing.

Abstract: The disclosed electrical stimulation system generates interventions to assist patients in complying with a diet. The wearable device includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 dermatome to a T12 dermatome or meridian of the patient, a C5 to a T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient and generate interventions. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols.

Abstract: There is provided a detection apparatus including: a heartbeat sensor that includes a plurality of electrodes and is configured to detect a first detection signal indicating heartbeat of a detection target via the plurality of electrodes; a pulse wave sensor configured to detect a second detection signal indicating a pulse wave of the detection target; and a processing unit configured to detect a pulse of the detection target on the basis of the first detection signal and the second detection signal.

Abstract: A device and method for analyzing of a disturbed pattern of pulse wave front results in a non-invasive, real-time diagnostic tool of arterial vascular performance on both a global and regional scale. The device provides a single number quantifying how well the arterial tree as a whole is coupled to receive and distribute a stroke volume of a single heartbeat. Changing heart rate, contractility, volume status, and afterload will change stroke volume and ejection time. Different vasculatures with different properties (e.g., size and intrinsic stiffness) will be best matched for different stroke volumes and ejection times to provide optimal coupling. The device will allow finding the optimal set of parameters for individual patient.

Abstract: An implant system for restoring and improving physiological intracardiac flow in a human heart is provided including an expandable balloon defining a fluid reservoir for positioning in a chamber of the human heart; a therapeutic apical base plate assembly attachable to the apex of the heart; and a tether assembly connected between the implant and the therapeutic apical base plate assembly.

Abstract: A translucent in-vivo indwelling device with a translucent region including a rare earth doped fluorapatite.

Abstract: An implant system for restoring and improving physiological intracardiac flow in a human heart is provided including an implant for positioning at least partially within a human heart; an apical base plate assembly attachable to the apex of the heart; a tether assembly comprising a tether connected between the implant and the therapeutic apical base plate assembly, and an adjustment assembly connected to the tether assembly to permit longitudinal movement of the tether assembly and implant relative to the base plate assembly.

Abstract: According to one embodiment, an electronic device includes an attaching member and a sensing circuit. The attaching member includes a face configured to be attached to a detection target. The sensing circuit includes a sensing interface provided on the face. The sensing circuit is configured to obtain information related to a contact state between the sensing interface and the detection target from the sensing interface.

Abstract: A compact system for performing laser ophthalmic surgery is disclosed. An embodiment of the system includes a mode-locked fiber oscillator-based ultra-short pulsed laser capable of producing laser pulses in the range of 1 nJ to 5 ?J at a pulse repetition rate of between 5 MHz and 25 MHz, a resonant optical scanner oscillating at a frequency of 200 Hz and 21000 Hz, a scan-line rotator, a movable XY-scan device, a z-scan device, and a controller configured to coordinate with the other components of the system to produce one or more desired incision patterns. The system also includes compact visualization optics for in-process monitoring using a beam-splitter inside the cone of a patient interface used to fixate the patient's eye during surgery. The system can be configured such that eye surgery is performed while the patient is either sitting upright, or lying on his or her back.

Abstract: A high dynamic range sensing front-end for bio-signal recording systems in accordance with embodiments of the invention are disclosed. In one embodiment, a bio-signal amplifier includes an input signal, where the input signal is modulated to a predetermined chopping frequency, a first amplifier stage, a parallel-RC circuit connected to the first amplifier stage and configured to generate a parallel-RC circuit output by selectively blocking an offset current, a second amplifier stage connected to the parallel-RC circuit that includes a second input configured to receive the parallel-RC circuit output and generate a second output that is an amplified version of the input signal with ripple-rejection. Further, the bio-signal amplifier can also include an auxiliary path configured for boosting input impedance by pre-charging at least one input capacitor. In addition, the bio-signal amplifier can also include a DC-servo feedback loop that includes an integrator that utilizes a duty-cycled resistor.

Abstract: In one embodiment, the present invention provides a device, wherein the device comprises a skin patch, configured to attach to the skin surface of the perineum of a subject suffering from premature ejaculation, wherein the skin patch contains electrodes configured to deliver electrical impulses transcutaneously to the bulbcavernosus muscle of the subject, wherein the transcutaneously delivered electrical impulses are configured to treat premature ejaculation.

Abstract: A phototherapy device comprising an outer garment wrap and a lamp assembly. The outer garment wrap has an inner surface. The lamp assembly has a base layer and a frame defining a plurality of inner chambers. A LED lamp assembly is positioned within each of the plurality of inner chambers. The lamp assembly is positioned on the inner surface of the outer garment wrap. A protective lamp envelope for receipt of the lamp assembly and attachment thereof to the outer garment wrap is likewise disclosed.

Abstract: A synthetic representation of a robot tool for display on a user interface of a robotic system. The synthetic representation may be used to show the position of a view volume of an image capture device with respect to the robot. The synthetic representation may also be used to find a tool that is outside of the field of view, to display range of motion limits for a tool, to remotely communicate information about the robot, and to detect collisions.