Abstract: A configuration is provided for firmly fixing a transmitting and receiving unit for IVUS and a transmitting and receiving unit for OCT in a probe of an imaging apparatus for diagnosis in which space saving is achieved. The probe includes a cylindrical housing in which an ultrasonic wave transmitting and receiving unit is arranged on a distal side and a light transmitting and receiving unit is arranged on a proximal side. Two signal wires are connected to the ultrasonic wave transmitting and receiving unit and which extend toward the proximal side substantially parallel to each other and which are arranged in the housing so as to cause the distance between the two signal wires to be smaller than a width of a ball lens portion of the light transmitting and receiving unit.

Abstract: An imaging apparatus for diagnosis is provided in which a simpler configuration enables an anatomical technique and a physiological technique to be used in combination. The imaging apparatus for diagnosis disclosed herein includes a first calculator for calculating a parameter indicating each deformation degree of measurement slit portions, by using a tomographic image including the measurement slit portions which are disposed at different positions in an axial direction of a probe unit and whose cross-sectional shape is deformed in response to a pressure applied to the probe unit, and a second calculator for calculating a value corresponding to a myocardial fractional flow reserve, based on the calculated parameter.

Abstract: A method includes storing three-dimensional image data acquired intravascularly via an optical coherence tomography (OCT) apparatus. The image data is analyzed to compute a probability estimate of stent presence at support positions appearing in an A-line. Stent strut locations are located in three-dimensional space based on the computed probability estimate of stent presence.

Abstract: A magnetic resonance imaging system configured for generating a three-dimensional representation of at least one breast of a patient includes: a device configured for generating a homogeneous magnetic field; a system of active gradient coils configured for generating at least one magnetic field gradient within a measurement volume; at least one breast holder having an internal space configured for positioning the at least one breast during an MRI scan within the measurement volume; at least one local coil system that includes at least one individual coil, the at least one individual coil configured to act as an antenna for receiving magnetic resonance signals; and at least one cushion configured for stabilizing the at least one breast by filling the internal space between the at least one breast and an external boundary of the internal space.

Abstract: The present invention pertains to a method and an apparatus for Raman spectroscopy of human tissue. Human tissue is illuminated with a laser emitting a first wavelength of light. A Raman signal is measured and optical properties are determined at this wavelength such that the measured Raman signal can be corrected based on determined optical properties. Determined optical properties may be the scattering coefficient and absorption coefficient of the tissue. A system for Raman spectroscopy of human tissue includes a frequency sweeping laser light source for illumination, and a filtered detector for collecting the Raman signal.

Abstract: A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, an applicator for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.

Abstract: In a method and system for planning a brachytherapy treatment, magnetic resonance image data of a patient are acquired by operating a magnetic resonance scanner according to a magnetic resonance sequence that designates an examination volume. An area of the patient is positioned in the examination volume such that the magnetic resonance image data contain at least a part of at least one applicator for the brachytherapy, which is located in the patient. The magnetic resonance sequence includes measurement parameters that lead to a contrast between the at least one applicator and surrounding tissue in the magnetic resonance image data. The position of the at least one applicator in the magnetic resonance image data is extracted, and a radiation treatment plan is created using the extracted position of the at least one applicator.

Abstract: An ultrasound diagnosis apparatus according to an embodiment includes a parameter setting unit, a Fly Thru image generating unit, and a controlling unit. The parameter setting unit sets a value of an image quality adjusting parameter used for generating a PVR image obtained by projecting the inside of a lumen from a predetermined viewpoint, on the basis of information about the lumen rendered in an MPR image generated by using volume data. The Fly Thru image generating unit generates the PVR image by using the value of the image quality adjusting parameter that was set. The controlling unit then causes a monitor to display the PVR image.

Abstract: Apparatus and methods are disclosed for multi-spectral imaging of tissue to obtain information about the distribution of fluorophores and chromophores in the tissue. Using specific spectral bands for illumination and specific spectral bands for detection, the signal-to-noise ratio and information related to the distribution of specific fluorophores is enhanced as compared to UV photography, which uses a single RGB image. Furthermore, the chromophore distribution information derived from the multi-spectral absorption images can be used to correct the fluorescence measurements. The combined fluorescence, absorption, and broadband reflectance data can be analyzed for disease diagnosis and skin feature detection.

Abstract: Systems and methods which generate a sequence of images using turbo spin echo magnetic resonance imaging which are retrospectively correlated with periodic motion occurring within a subject being imaged are described. In one embodiment, k-space measurements (or the measurements from which images are formed) are captured during, and correlated with, different phases in a cardiac cycle of the subject. With this sequence, the images that are produced are able to show, and/or compensate for, motion correlated with the cardiac cycle of the subject.

Abstract: An X-ray imaging apparatus is provided. The X-ray imaging apparatus includes an overlapping unit configured to overlap a 2-Dimensional (2D) blood vessel image with a 2D fluoroscopy image to acquire a 2D roadmap image corresponding to a first position, a detector configured to detect a location of a surgical tool from the 2D roadmap image corresponding to the first position, and detect a blood vessel corresponding to the location of the surgical tool from a 3-Dimensional (3D) blood vessel image, and a User Interface (UI) processor configured to mark the 2D roadmap image with the location of the surgical tool with an identifier in the detected blood vessel.

Abstract: Cardiac catheterization is carried out by introducing a catheter into the coronary sinus, acquiring a first set of 2-dimensional images of the catheter, thereafter acquiring a second set of 2-dimensional images of the catheter, and creating respective 2-dimensional models of the catheter in synchronized frames of the first set and the second set. The 2-dimensional models include respective tracked 2-dimensional paths of the catheter. The first and second sets are synchronized by identifying frames that are in respective phases of the cardiorespiratory cycle. First and second 3-dimensional models of the catheter are constructed from the synchronized frames, and geometrically transformed to minimize a distance function between the two models.

Abstract: An acoustic driver system for use in applying an oscillating stress to a subject undergoing a magnetic resonance elastography (MRE) examination includes a flexible passive driver located in the bore of the magnet and in contact with the subject. A remotely located active driver is acoustically coupled to the passive driver and produces acoustic energy in response to an applied current. The passive driver produces shear waves in response to the acoustic energy and are directed into the body of the subject undergoing the MRE examination.

Abstract: A specimen information acquisition apparatus includes a signal processor which can selectively operate in first and second modes. In the first mode, when a first group represents a group of devices among receiving devices and a second group represents at least a fraction of a group of devices other than the first group, a photoacoustic image and an ultrasonic image are obtained based on received signals from the first group and the second group, respectively. In the second mode, when a third group represents a group of devices having at least a fraction of a group of devices other than the first group and a fourth group represents at least a fraction of a group of devices other than the third group, a photoacoustic image and an ultrasonic image are obtained based on received signals from the third group and the fourth group, respectively.

Abstract: A medical device system is provided. The medical device system includes a positioning apparatus having a body section and an upper section, the upper section slidably coupled to the body section such that the upper section slidably moves relative to the body section. The medical device also includes a flexible guide rod extending through the positioning apparatus and configured to be inserted into a passage of a respiratory system of a subject. The flexible guide rod includes a visible light emitter configured to emit visible light within the passage of the respiratory system and is visible outside the subject.

Abstract: A method for positioning a medical device in a respiratory system is provided. The method includes providing a medical device system including a positioning apparatus having a body section and an upper section, the upper section slidably coupled to the body section, a flexible guide rod, a visible light source, and a medical device for treating the patient slidably receivable on the flexible guide rod. The method also includes inserting the flexible guide rod into a treatment portion of a respiratory system, emitting visible light from the visible light source, visually observing, outside the patient's body, the emitted visible light, and slidably moving the medical device distally along the flexible guide rod toward the distal end of the flexible guide rod to a selected position relative to the distal end of the flexible guide rod and within said treatment portion of the respiratory system of the patient's body.

Abstract: A photoacoustic imaging method that enables photoacoustic images to be displayed at high speed is provided. The photoacoustic imaging method scans a subject with a light beam, detects acoustic waves generated within the subject due to the scanning of light to obtain acoustic wave detected signals, and generates volume data that represent three dimensional photoacoustic images of the subject based on the acoustic wave detected signals. Photoacoustic projection images projected in the direction of irradiation depth of the light are generated, prior to the volume data being generated and concurrently with the scanning of the light. The photoacoustic projection images are displayed.

Abstract: An ultrasound probe includes a therapeutic ultrasound transducer, a slot disposed in the therapeutic ultrasound transducer, and a first diagnostic ultrasound transducer disposed in the slot and configured to move along the slot.

Abstract: An apparatus and methods to quantify the volume of urine in a human bladder with a limited number of acoustic beams is disclosed. In a first version a plurality of narrow ultrasound beams is transmitted in different directions towards the bladder. Returning echoes are converted to digital form and stored in memory. A volume display on the apparatus allows to define the optimal apposition of the transducer assembly. Signal processing software automatically determines the bladder Depth D and Height H and computes the volume of urine. In a second version, a single wide angle ultrasound beam transducer transmits ultrasounds signals at a fundamental frequency to quantify the urine volume. Return signals originating from a depth beyond the usual position of the posterior wall depth of a filled bladder are analyzed for presence of higher harmonic signals, which in turn are related to the presence or absence of urine.

Abstract: In an ultrasound diagnostic apparatus, a vascular wall tracker tracks pulsation-originated vascular wall movement based on reception signals obtained through transmission and reception of ultrasonic beams by an ultrasound probe to and from a subject, and a pulsating timing determiner determines pulsating timing by detecting pulsation-originated periodic changes in the vascular wall movement tracked by the vascular wall tracker in each of sound rays, obtaining a detection time point as a pulsating timing candidate in each of the sound rays, and statistically analyzing pulsating timing candidates in the respective sound rays within a single pulse duration. The ultrasound diagnostic apparatus can accurately measure the state of a blood vessel merely using information obtained through ultrasound examination without electrocardiographic waveforms.