Abstract: Combinations of sunscreens comprising at least one specific anti uv-B filter with triazinoaniline structure and at least one specific anti UV-A filter selected from filters with benzoxazol substituted triazinoaniline structure and a long chain alkyl ester of a benzoxazolyl-aminophenyl-cyanoacrylic acid. Cosmetic and dermatological compositions containing them, optionally in combination with vitamins and/or other anti UV-A and anti UV-B filters.
Abstract: The present invention relates to novel compositions containing a mixture of two or three bioflavonols like isoquercetin, quercetin-4′-glycoside, rutin and quercetin, which show differences in their pharmacokinetics. These compositions are useful as food supplements possessing preventive properties against damage to human tissues due to their antioxidant properties. Furthermore, these compositions secure a continuum of the presence of bioflavonols having the same aglycone in human plasma over an extended period of time.
Abstract: A method of pulmonary delivery of a medicament, for example a dopamine precursor or a dopamine agonist, which includes administering to the respiratory tract of a patient in need of rescue therapy particles comprising an effective amount of a medicament. The particles are delivered to the pulmonary system and are released into the blood stream and delivered to the medicament's site of action in a time sufficiently short to provide the rescue therapy. In addition to the medicament, the particles can include other materials such as, for example, phospholipids, amino acids, combinations thereof and others. Preferred particles have a tap density of less than about 0.4 g/cm3.
Abstract: The invention provides a method for inhibiting the binding of a biguanide disinfectant in aqueous solution to a poly(ethylene) solid in contact with said solution comprising providing in said solution an amount of cyclodextrin sufficient to inhibit binding of the biguanide disinfectant to the poly(ethylene) solid.
Type:
Grant
Filed:
July 27, 2001
Date of Patent:
February 4, 2003
Assignee:
Bausch & Lomb Incorporated
Inventors:
Erning Xia, Richard V. Smerbeck, John Denick, Jr.
Abstract: The present invention is directed to a novel pharmaceutical composition of polymorph B which has been found to be stable and palatable for long term commercial usage.
Abstract: The present invention relates to topical whitening compositions comprising a whitening effective amount of an Ascomycete-derived melanin-degrading enzyme extract and methods of preparing the composition. The compositions provide a whitening effect which occurs by degrading melanin in the skin, yet the compositions themselves do not turn dark in color. The enzyme extract can be derived from Aspergillus fumigatus or from Saccharomyces cerevisiae, and is added to the compositions of the present invention. The compositions containing the enzyme extract are twice as effective as kojic acid in producing a whitening effect on the skin.
Type:
Grant
Filed:
February 14, 2001
Date of Patent:
February 4, 2003
Assignee:
Color Access, Inc.
Inventors:
Thomas Mammone, Steven F. Schnittger, Kenneth D. Marenus, Daniel H. Maes
Abstract: An oral pharmaceutical dosage form including a mixture of a delay release formulation of a non-steroidal anti-inflammatory drug (NSAID) and a mixture containing a prostaglandin and one or more excipients.
Type:
Grant
Filed:
April 24, 2001
Date of Patent:
February 4, 2003
Assignee:
Norton Healthcare Ltd
Inventors:
Austen John Woolfe, Gordon McIntyre, Nitin Vadilal Sheth
Abstract: Disclosed is an osmotic pharmaceutical delivery system comprising (a) a semi-permeable wall that maintains its integrity during pharmaceutical delivery and which has at least one passage therethrough; b) a single, homogeneous composition within said wall, which composition consists essentially of (i) a pharmaceutically active agent, (ii) at least one non-swelling solubilizing agent which enhances the solubility of the pharmaceutically active agent; (iii) at least one non-swelling osmotic agent and (iv) a non-swelling wicking agent dispersed throughout the composition which enhances the surface area contact of the pharmaceutical agent with the incoming aqueous fluid.
Type:
Grant
Filed:
December 28, 2001
Date of Patent:
February 4, 2003
Assignee:
Shire Laboratories, Inc.
Inventors:
Edward M. Rudnic, Beth A. Burnside, Henry H. Flanner, Sandra E. Wassink, Richard A. Couch, Jill E. Pinkett
Abstract: Low-viscosity cosmetic or dermatological preparations of the oil-in-water type, which comprise an oil phase, in which hydrophobic and/or amphiphilic solids are incorporated, and a water phase, where the difference in density between the oil phase and the water phase (determinable using a computerized digital density meter of the type DMA 45 from chempro/PA at 25° C.) is not greater than 0.01 g·cm−3, and method of stabilizing O/W formulations.
Abstract: Composition of matter for application to a body surface or membrane to administer fluoxetine by permeation through the body surface or membrane, the composition comprising fluoxetine to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. A preferred embodiment is directed to the transdermal administration of fluoxetine at reduced skin irritation levels wherein fluoxetine, preferably provided as fluoxetine acetate, is coadministered with a corticosteroid such as hydrocortisone. Also disclosed are drug delivery devices containing the fluoxetine or fluoxetine and enhancer composition and methods for the transdermal administration of the fluoxetine and fluoxetine/enhancer composition.
Type:
Grant
Filed:
July 14, 1997
Date of Patent:
January 28, 2003
Assignee:
Alza Corporation
Inventors:
Robert M. Gale, Melinda K. Nelson, Michel J. N. Cormier, Suneel K. Gupta, Patricia S. Campbell
Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
Type:
Grant
Filed:
February 18, 2000
Date of Patent:
January 28, 2003
Assignee:
SmithKline Beecham Corp.
Inventors:
Ian C. Ashurst, Ignatius Loy Britto, Craig Steven Herman, Li Li-Bovet, Michael Thomas Riebe
Abstract: A metered dose inhaler having part or all of its internal surfaces coated with one or more fluorocarbon polymers, optionally in combination with one or more non-fluorocarbon polymers, for dispensing an inhalation drug formulation comprising beclomethasone dipropionate or a physiologically acceptable solvate thereof, and a fluorocarbon propellant, optionally in combination with one or more other pharmacologically active agents or one or more excipients.
Type:
Grant
Filed:
February 18, 2000
Date of Patent:
January 28, 2003
Assignee:
SmithKline Beecham Corp.
Inventors:
Ignatius Loy Britto, Ian Car Ashurst, Craig Steven Herman, Li Li-Bovet, Michael Thomas Riebe
Abstract: The invention concerns a cosmetic composition comprising a specific functionalized organopolysiloxane which is linear or cyclic. Said functionalized organopolysiloxane is used as emollient and/or carrier and/or anti-transfer agent in cosmetic compositions.
Type:
Grant
Filed:
April 13, 2000
Date of Patent:
January 21, 2003
Inventors:
Paul Branlard, Gérard Mignani, Claudie Willemin, Philippe Olier
Abstract: A threadlike or ribbonlike elastic strand is provided with a substantially continuous filament of adhesive helically wrapped around the elastic strand. The elastic strand is suitable for use in disposable absorbent products such as diapers and adult incontinent products. Also disclosed is a method and apparatus for making such adhesive-wrapped elastic strands.
Type:
Grant
Filed:
April 26, 1995
Date of Patent:
January 21, 2003
Assignee:
Kimberly-Clark Worldwide, Inc.
Inventors:
Neal Alan Rollins, John Anthony Rooyakkers
Abstract: According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible dry powder pharmaceutical-based composition is one having a moisture content of less than about 10% by weight (% w) water, usually below about 5% w and preferably less than about 3% w; a particle size of about 1.0-5.0 &mgr;m mass median diameter (MMD), usually 1.0-4.0 &mgr;m MMD, and preferably 1.0-3.0 &mgr;m MMD; a delivered dose of about >30%, usually >40%, preferably >50%, and most preferred >60%; and an aerosol particle size distribution of about 1.0-5.0 &mgr;m mass median aerodynamic diameter (MMAD), usually 1.5-4.5 &mgr;m MMAD, and preferably 1.5-4.0 MMAD. Such composition are of pharmaceutical grade purity.
Type:
Grant
Filed:
October 26, 1999
Date of Patent:
January 21, 2003
Assignee:
Inhale Therapeutic Systems, Inc.
Inventors:
Robert M. Platz, John S. Patton, Linda Foster, Mohammed Eljamal
Abstract: An antibacterial, antifungal or antialgal article includes an antibacterial, antifungal or antialgal component, for example, silver and copper, an alloy thereof or a compound thereof diffused from a surface into the inside of the surface portion of an article, for example, a metal, glass or ceramic article.
Abstract: Oral composition comprising a co-ground of at least two ingredients which are co-ground without the use of solvents and wherein the co-ground comprises each of at least two ingredients at a level of at least 5% by weight of the total weight of the co-ground, characterised in that the composition is an aqueous composition.
Type:
Grant
Filed:
August 21, 2001
Date of Patent:
January 14, 2003
Assignee:
Unilever Home & Personal Care USA, a division of Conopco,
Inc.
Abstract: A treatment patch includes a patch body having a contacting surface for placing on a skin surface of a treating tissues of a user, and a dressing layer which is provided on the contacting surface containing positively charged metallic ions for depolarizing negative ions accumulated under the skin surface of the treating tissues, wherein a far infrared ray emitter disposed on the. patch body for emitting far infrared rays penetrating into the treating tissues through the skin surface so as to provide an ion passway between the skin surface in contact with the dressing layer of the patch body and the treating tissues so as to enhance the depolarization of the positively charged ions of the dressing layer with the negative ions around the treating tissues of the user to relieve pain.
Abstract: The present invention provides improved chlortetracycline-containing animal feed compositions and processes and apparatuses for their preparation. In certain embodiments, raw fermentation broth comprising chlortetracycline is divided into two portions. The first portion is mixed with a compound that complexes chlortetracycline. The second portion is acidified and the solids are removed. The acidified liquid is treated with a complexing agent to produced a chlortetracycline complex. The first and second portions thus treated are then mixed and the mixture is passed on to a filter press or other means for separation of the solids to produce a wet cake comprising complexed chlortetracycline. In alternative embodiments, the second portion may be acidified and filtered and admixed with the first portion prior to the complexing step. The resulting mixture is passed on to a filter press or other means for separation of the solids.
Abstract: A product for application to the skin includes a container and a composition within the container including a cosmetic or therapeutic active ingredient. Sometime after first use, the application surface of the composition changes from a first visual appearance to a second visual appearance due to a change in the composition.
Type:
Grant
Filed:
May 16, 2001
Date of Patent:
January 14, 2003
Assignee:
The Gillette Company
Inventors:
Philip William Ambler, Philip Norman Hole, Michael J. Moloney, Cheryl L. Galante, Iris Davis Gersten, James L. Solan, Hermes van der Lee