Abstract: Aspects of the present technology comprise a positioning and stabilising structure to hold a seal-forming structure in a therapeutically effective position on a head of a patient. The seal-forming structure may be constructed and arranged to form a seal with a region of the patient's face surrounding an entrance to the patient's airways for sealed delivery of a flow of air at a therapeutic pressure of at least 4 cmH2O with respect to ambient air pressure throughout the patient's respiratory cycle in use. The positioning and stabilising structure may comprise at least one gas delivery tube to deliver the flow of air to the entrance of a patient's airways via the seal-forming structure. The positioning and stabilising structure may comprise an adjustment mechanism for adjustment of a length of the at least one gas delivery tube to enable the positioning and stabilising structure to fit different size heads.

Abstract: A method for performing cold atmospheric plasma treatment of respiratory infections or lung cancer having a source of a carrier gas, a cold atmospheric plasma generator connected to the source of carrier gas, a source of compressed air, a humidifier connected to the source of compressed air, a source of oxygen, a ventilator having inputs connected to an output of the humidifier and the source of oxygen, a mixer having an interior chamber formed from a dielectric, an active electrode inside the interior chamber, and an outer electrode connected to ground, wherein the mixer has a fluid input port connected to a gas output of the cold atmospheric plasma generator and an output of the ventilator, and a delivery member connected to an output of the mixer for delivering combined humidified air and cold atmospheric plasma to a respiratory system of a patient.

Abstract: In one aspect of the present disclosure, an airway device is disclosed that includes a bite block and a depressor section. The bite block has proximal and distal ends and is configured and dimensioned for positioning between a patient's upper and lower teeth. The depressor section also has proximal and distal ends and extends distally from the bite block. The depressor section includes upper and lower members that are separated by a web as well as a stop. The lower member includes a first portion having a generally linear configuration and a second portion having an arcuate configuration, and the stop depends transversely from the first portion of the lower member.

Abstract: A portable oxygen concentrator designed for medical use where the adsorbent beds, are designed to be replaced by a patient. The concentrator is designed so that the power supply and adsorbent bed mount is one module and the compressor and air filter are part of another module configured to provide a unitary cooling and air supply system. Replacement beds may be installed easily by patients, and all gas seals will function properly after installation.

Abstract: A finger exerciser includes: a frame on which a palm of a subject to be put; a movable section; a first fixing element; and a second fixing element. The movable is configured to move a first finger group of a subject. The first fixing element is configured to fix a position of the first finger group to the movable section. The second fixing element is configured to fix a position of a second finger group to the frame and has a band-like member including at least two attachment parts apart from each other in a longitudinal direction of the band-like member. The band-like member is attached to the frame at the attachment parts and includes a holder whose location to the frame is changeable. The band-like member is configured to hold the second finger group in a state where the band-like member is attached to the frame.

Abstract: A droplet delivery device with a small volume drug ampoule and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device is configured to facilitate the ejection of small, e.g., single use, volumes of a therapeutic agent. The droplet delivery device includes a housing, a mouthpiece, a small volume drug ampoule, an ejector mechanism, and at least one differential pressure sensor. The delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 ?m, so as to target the pulmonary system of the user.

Abstract: An apparatus to remove liquid from a ventilation system can include a housing, a first port extending into an interior volume of the housing and a second port extending toward the first tube, into the interior volume, separated from the first port by a gap that is at least 5 mm in length, such that ventilating fluid transfers from the first port to the second while secretions and condensate escape through the gap, to be trapped in the housing. The first port joins with a ventilator. The second port joins with an intubation tube coupled to a tracheostomy or endotracheal tube. An extraction port is in a floor of the housing so that accumulated liquids in the housing can drain downward and out the extraction port, while minimizing positive end expiratory pressure loss in the ventilation system, and without exposing caregivers to biological material in the drained liquid.

Abstract: A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit.

Abstract: A device is disclosed for the preparation of nebulised droplets, for inhalation. The device has: a surface acoustic wave (SAW) transmission surface; a SAW transducer adapted to generate and propagate SAWs along the SAW transmission surface; and an array of cavities opening at the SAW transmission surface for containing a liquid. In operation, SAWs propagating along the SAW transmission surface interact with the liquid in the cavities to produce nebulised droplets of the liquid. Operation of the device results in a nebulised plume of droplets of average diameter in the range 1-5 ?m.

Abstract: A mesh nebulizer includes a main body with a recessed portion opening upward. The nebulizer includes a cap that covers an upper portion of the main body and a replacement element separate from the main body and the cap and detachably mountable in the recessed portion of the main body while being separated from the cap prior to operation of the nebulizer. The replacement element includes a sheet including a mesh portion, a bottom plate portion, and a sidewall portion. When the cap is closed with respect to the main body, the cap presses the upper edge of the sidewall portion of the replacement element toward an edge portion around the recessed portion to position the replacement element with respect to a longitudinal axis direction of the main body.

Abstract: A respiratory ventilation apparatus configured to deliver a respiratory gas to a patient interface is provided. The apparatus may include a gas pressurization unit configured to generate a pressurized respiratory gas, a gas inlet port configured to introduce the respiratory gas into the respiratory ventilation apparatus, a gas outlet port configured to discharge the pressurized respiratory gas to a respiration tube, a detection module configured to detect the pressure of the pressurized respiratory gas, at least one non-volatile memory configured to store a plurality of parameters and a plurality of programs, and one or more controllers. The one or more controllers may be configured to initiate the respiratory ventilation apparatus upon a boot operation, and/or initiate a program that constantly reads information from the detection module, and controls the pressure of the pressurized respiratory gas using the information read from the detection module and at least one parameter.

Abstract: The control-monitor, used in combination with a percussive ventilation breathing head and internal reciprocating injector shuttle, includes in a casing a generator, sensory pulse amplitude, frequency and MAP modules and a gas amplitude and pulsatile frequency control knobs. First and second AMP control indicia include a bent conical AMP indicia (a wide span indicating greater amplitude, a narrow span indicating lesser amplitude) and a single waveform with an adjacent double-headed arrow vertical line. First and second F control indicia include a bent conical F indicia (a wide span indicating greater F and a narrow span indicating lesser F) and multiple waveforms with an adjacent double-headed arrow horizontal line.

Abstract: A mask assembly for use as part of an apparatus for supplying a flow of respiratory gases to a user is disclosed. The mask assembly includes a mask body having an inlet through which said flow of respiratory gases are provided to the interior of said mask body. A mask seal assembly comprising a seal of flexible material and a clip of rigid material is attached to the body. The seal has a first side and a second side. The first side of the seal is shaped to approximately match the contours of a user's face and in use substantially seal against a user's face. The second side is attached to the clip. The clip provides an interface extending substantially the full perimeter or periphery of the mask seal assembly for releasably attaching the mask seal assembly to the mask body. The clip comprises a bridging portion spanning outwards from the perimeter or periphery of the mask body to space at least a portion of the second side of the seal outwards from the perimeter or periphery of the mask body.

Abstract: A ventilator system, comprising: an inhalation pathway comprising an ambient air inlet, a bi-directional emergency valve, and a dynamic blower; and an exhalation pathway comprising a bi-directional exhalation valve and an exhalation port; wherein when a blockage occurs in the inhalation pathway, ambient air can be drawn from the exhalation port and through the bi-directional exhalation valve, and during exhalation exhalant exits the ventilator through the bi-directional exhalation valve and the exhalation port; wherein when a blockage occurs in the exhalation pathway, inhalant is delivered by the dynamic blower, and during exhalation the dynamic blower lowers its speed or stops and the exhalant exits the ventilator through the bi-directional emergency valve, the dynamic blower, and the ambient air inlet.

Abstract: Exercise robot suitable for rehabilitation and methods of its operation are provided. In particular a method in which the exercise robot learns an exercise movement on the basis of movements conducted by the aid of a human assistant holding the leg of a patient and moving the leg with muscular form to conduct an exercise movement. The rehabilitation robot actively accompanies the exercise movement in an active compliance mode and records the movement so as to determine an exercise movement stored in the control unit of the device. The rehabilitation robot can then produce the determined exercise in an exercise mode.

Abstract: A system for delivery of aerosol therapy includes a housing defining a chamber. The housing has a base, a top and a main body extending therebetween. An ambient air inlet is adjacent the base and is normally closed by an inlet valve. The housing has a patient port. Exhaled air is exhausted through valves in a mouthpiece or a face mask to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.

Abstract: In one embodiment, a method for accurate leak estimation in a flow generation system includes measuring a total flow through the flow generation system, measuring a pressure in in the primary flow circuit of the flow generation system, determining when the measured pressure is within a predetermined threshold of EPAP, and calculating an intentional leak flowrate and an unintentional leak flowrate based on the relationship QFS(t)=QIL(t)+QUL(t) when the measured pressure is within the predetermined threshold. In another embodiment, a flow generation system includes in one embodiment an airflow generator connected in-line to a flow sensor, a pressure sensor and a patient interface connection by a first gas flow circuit, and a controller electrically coupled to the airflow generator, the flow sensor and the pressure sensor.

Abstract: A patient interface system includes a nasal seal of flexible material to communicate with at least one airway of the patient, and a primary headgear from which the nasal seal is suspended, said primary headgear having at least one aperture though which at least a portion of the nasal seal is inserted with the primary headgear wrapping about at least one portion of the nasal seal in a sling-like fashion.

Abstract: A powered air purifying respirator composing 2-channel structure for air support includes: a mask unit that is worn on a face to surround a mouth or nostrils of a user; a generator unit that causes outside air to flow in and supplies the air to the mask unit; and first and second connector units that are formed to provide channels of the air by being connected to the mask unit and the generator unit at both sides of the first and second connectors, where the generator unit includes a fan driving module having first and second air supply holes at both sides of the fan driving module, the first and second air supply holes communicating with end portions of the first and second connector units.

Abstract: An expandable endotracheal tube includes a shaft that has an airway. The expandable endotracheal tube also includes an expandable segment mounted to a distal end of the shaft. The expandable segment includes an expandable membrane and a constant force spring positioned within the expandable membrane. The constant force spring has a compressed configuration to allow for placement of the expandable endotracheal tube within a patient and an expanded configuration in which the expandable membrane forms a seal with a trachea of the patient to enable positive pressure ventilation.