Abstract: Systems and methods relating to dialysis therapy, particularly continuous flow dialysis therapy, are provided. The present invention includes a single closed fluid path along which a minimal amount of therapy fluid including dialysate is fed into, continuously circulated and cleaned such that a therapeutic effective amount of solutes, excess water and the like can be removed from the patient connected to the closed fluid loop during treatment.

Abstract: Methods and apparatus are disclosed for producing hollow fiber membrane-containing filters. The methods include laying a plurality of hollow fibers in a first portion of a filter housing to form a bundle, forming first and second portions into a filter housing, sealing the portions together, connecting the plurality of hollow fibers together at at least one end of the filter housing, connecting the hollow fibers to the filter housing, and simultaneously adhering the first and second portions of the filter housing together by applying a potting compound thereto, and cutting the ends of the hollow fibers at at least one end thereof, whereby the hollow fibers include open ends.