Abstract: A tube filling machine, including a conveying device rotating about a pair of axes defining a plane and having a plurality of holding elements in each of which a tube can be inserted. The tubes can be conveyed through individual works stations. In order to permit a simple modification and adaptation of the orientation of the tubes during their passage through the tube filling machine, the plane defined by the axes is inclined at an angle .alpha. to the horizontal, and each tube is so held in its holding element that its longitudinal axis is inclined at an angle .beta. relative to the defined plane. The angle .alpha. and the angle .beta. are preferably in the range 20 to 70.degree..