Abstract: A protein having molecular weight of approximately 16 kD which is also cleaved into a protein having a molecular weight of 15 kD is disclosed. This protein is referred to as viral protein U and produced by the vpu gene. It is disclosed that this protein has antigenic determinants and can be used to screen for people having the HIV-1 virus.
Type:
Grant
Filed:
May 12, 1988
Date of Patent:
August 27, 1991
Assignee:
Dana Farber Cancer Institute
Inventors:
William A. Haseltine, Ernest Terwilliger, Eric Cohen