Abstract: A filter for processing a biological fluid is disclosed comprising at least two filter elements wherein the surface of one filter element is substantially non-hydroxylated and has a nitrogen-to-oxygen ratio in the range of from at least 0.01 to less than about 1.00, and the surface of the other filter element is hydroxylated relative to the bulk of the element.

Abstract: A filtration system includes an outer casing (210) that houses a plurality of elongated inner casings (220A–220F), which in turn house a plurality of filtration membranes. The outer casing, inner casing, and filtration membranes are disposed relative to one another to provide a three-flow channel system that provides additional feed fluid at one or more membrane couplings between membranes of the same inner casing. Ths arrangement defines a feed fluid flow path in which a feed fluid exiting from an upstream filter into a downstream filter is diluted by additional feed fluid.

Abstract: Apparatus for contacting first and second fluids at elevated pressures with a membrane such that one or more components of one of the fluids passes through the membrane into the other fluid, comprising a housing e.g. a pressure vessel (4), and a membrane module (20) housed in the pressure vessel and having a first fluid inlet (8a) and a first fluid outlet (8b) and a second fluid inlet (9a) and a second fluid outlet (9b), wherein a seal (61) extends round the membrane module and seals between an outside wall of the membrane module and an inside wall of the pressure vessel so as to separate the first fluid inlet from the first fluid outlet.

Abstract: This invention provides a method and apparatus for a hemodiafiltration delivery module that is used in conjunction with a UF controlled dialysis machine to enable hemodiafiltration therapy to be performed. The advantage is that one can fully utilize a current functioning dialysis machine to perform a hemodiafiltration therapy as opposed to purchasing a completely new machine that offers this capability.

Abstract: The invention relates to a composite membrane (1) consisting of a flat support body (2) comprising relative big through flow holes (3) and on which at least one separating layer is applied as a membrane layer (4) having a given number of pores and pore sizes. In order to regulate the temperature of the support body, said support body (2) is connected to a device (5) that can be regulated by a regulating device (S) with the purpose of supplying a predetermined energy to the support body (2) and/or diverting energy from the support body (2). The membrane layer (4) is applied on the support body (2) in a heat-conductive manner so that any change in the temperature of the support body provokes a change in the temperature of the membrane layer.

Abstract: A barrier filter useful for aseptically discharging both gaseous and liquid fluids from a chemical process system is disclosed The barrier filter comprises, within a common enclosure, one or several filter membranes having singularly or collectively a mixture or hydrophobic and hydrophilic regions. The common enclosure of the barrier filter is provided with a fluid inlet and a fluid outlet. All filter membranes are located within the fluid path between the fluid inlet and the fluid outlet. A variety of membrane-based systems, into which such barrier filter is installed, are also disclosed.

Abstract: Porous poly(aryl ether ketone) (PAEK) articles are prepared from PAEK/polyimide blends by selective chemical decomposition and subsequent removal of the polyimide phase. Porous PAEK articles exhibit highly interconnected pore structure and a narrow pore size distribution. The porous PAEK articles of the present invention can be utilized as a porous media for a broad range of applications, including membranes for fluid separations, such as microfiltration, ultrafiltration, nanofiltration, and as a sorption media.

Abstract: The present invention is an improved feed spacer, spiral wound element incorporating said feed spacer, filtration system and a method for making and using the same. In one embodiment the present invention includes an improved spiral wound element having: a central collection tube with a plurality of openings along its length to receive permeate; at least one filtration envelope extending outwardly from and wound about the tube and at least one feed spacer sheet wound about the collection tube wherein the feed spacer sheet being in planar contact with the outer surface of at least one filtration envelope.

Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system.

Abstract: A method for stretching a hollow fibre while making a stretched filtering membrane from a precursor involves wrapping the hollow fibre around a structure and modifying the structure such that at least portions of the hollow fibre are forced to elongated. For example, the hollow fibre may be wrapped around around two or more supports and the distance between adjacent supports increased. This produces first portions of the hollow fibre stretched to a first elongation and porous to a first porosity and second portions of the hollow fibre that are not stretched or are stretched to a second elongation less than the first elongation and that remain non-porous or become porous to a second porosity which is less than the first porosity. The membrane may be made into a module with second portions of the membranes located at points where the membranes exit the potting material or at turns in loops of the fibres, if any. In various embodiments, the fibre is potted into modules before or after it is stretched.

Abstract: The process of heavy metals removal from the waste water using silica dispersion without mixing silica dispersion with the waste water. This is achieved due to the membrane device where silica dispersion and waste water stream are separated by membrane with pore sizes smaller that size of the silica particles. The process is organized as counter-flow, which means that silica dispersion and waste water flow in the opposite directions. This provides the maximum utilization of the adsorption capacity corresponding to the adsorbent being in equilibrium with the high initial concentration of the contaminant in distinction from the low utilization when adsorbent works in equilibrium with the low output concentration. In the particular instance the membrane device comprises a lumen of a bundle of hollow fibers with silica dispersion flowing either inside or outside of the fibers and wastewater flowing on the opposite side of the fiber membrane. This process eliminates step of separating silica from the wastewater.

Abstract: The present invention provides for a multiple well filter plate and method of producing same, the multiple well filter plate comprising a molded plate and a filter sealed via an adhesive, the method particularly adapted for producing multiple well filter plate having substantial well densities and small volume sample wells.

Abstract: The present invention relates to an asymmetric porous polytetrafluoroethylene membrane comprising a dense skin layer and a continuously foamed porous layer, (1) the dense skin layer having a surface roughness Ra of 20 to 165 nm; (2) the dense skin layer having a contact angle for water of 120 to 135°; (3) the porous layer having a maximum pore diameter of 0.03 to 1.0 ?m; and (4) the membrane having a total porosity of 20 to 70%. The asymmetric porous PTFE membrane has an ability to separate each liquid component from a liquid-liquid homogeneous mixture in addition to known properties such as water permeability resistance, gas permeability, sealing property and electric property, wherein change of these properties over time is small.

Abstract: A method for carrying out therapeutic apheresis comprises separating plasma from whole blood in-vivo and removing selected disease-related components from the separated plasma. Apparatus for carrying out therapeutic apheresis includes a filter device for being implanted in a blood vessel for carrying out in-vivo plasma separation having one or more elongated hollow tubes and a plurality of elongated hollow microporous fibers capable of separating plasma from whole blood at pressure and blood flow within a patient's vein, a multiple lumen catheter secured to the proximal end of the filter device having one or more lumens in fluid communication with the interior of said one or more hollow tubes and a plasma return lumen, and therapeutic apheresis apparatus for removing and/or separating selected disease-related components from the separated plasma and means for directing plasma between said catheter and the selective component removal apparatus.

Abstract: There is disclosed a process and device for Forward Osmosis (FO) Pressurized Device (FOPD) in general and one hydraulically coupled to a reverse osmosis (RO device for a FOPRO (Forward Osmosis Pressurized Reverse Osmosis). Specifically, there is disclosed a passive device (that is, not needed energy input) for using forward osmosis to generate significant hydraulic pressure that can be used to drive a reverse osmosis process, wherein the reverse osmosis process (not needed external energy to run pumps) can separate salt from salt water to generate potable water from water with high salt content (such as sea water, urine, sweat, brackish water and the like).

Abstract: A device for concentrating and/or purifying macromolecules in liquids is disclosed wherein the concentration/purification is accomplished by a membrane separating concentration and filtration chambers, the membrane and chambers being compressively held in fluid-tight relationship by sliding engagement with a sleeve-like housing. A method for assembling such a device is also disclosed.

Abstract: A filter device made of less expensive material than comparable filter devices heretofore has basic filter components plus some unique design aspects and an additional ring component. The ring provides an interface inside the filter which enables the potting compound to adhere to the filter and create a seal between a first and second fluid compartment within the filter. An embedded region of the ring possesses a detailed geometry which helps ensure that a delamination would be localized and unable to propagate from the first to the second compartment, maintaining the structural integrity of the filter device. To ensure that the sealing interface remains intact and free from delamination, the ring is subjected to a surface treatment, which modifies the surface energy of the ring. This modified surface energy of the ring allows the hydrophilic potting compound to more effectively bond to the modified hydrophobic ring.

Abstract: The present invention relates to a process for recovering copper from solutions from the recovery of iodine from industrial wastes from the production of ionic and non-ionic iodinated X-ray contrast agents by use of chelating resins suitable for removing copper from aqueous solutions. The absorbed copper is displaced by treating the resins with a 10% hydrochloric or sulfuric acid solution.

Abstract: The invention includes novel anion exchange membranes formed by in situ polymerization of at least one monomer, polymer or copolymer on a woven support membrane and their methods of formation. The woven support membrane is preferably a woven PVC membrane. The invention also includes novel cation exchange membranes with or without woven support membranes and their methods of formation. The invention encompasses a process for using the membranes in electrodialysis of ionic solutions and in particular industrial effluents or brackish water or seawater. The electrodialysis process need not include a step to remove excess ions prior to electrodialysis and produces less waste by-product and/or by-products which can be recycled.

Abstract: A water treatment apparatus according to the present invention includes a plurality of composite reverse osmosis membrane modules arranged in multi-stages, each of the modules including a porous support and a polyamide skin layer formed on the porous support. In this apparatus, the module at the final stage is supplied with some of permeated water obtained from at least one module preceding the module at the final-stage, and a rest of the permeated water is discharged from or recovered in the apparatus along with permeated water obtained from the final-stage module.