Patents Examined by Kagnew H Gebreysesus
  • Modification of protein glycosylation in methylotrophic yeast
    Patent number: 8058053
    Abstract: The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: November 15, 2011
    Assignees: VIB, VZW, Universiteit Gent, Research Corporation Technologies, Inc.
    Inventors: Roland Contreras, Nico L. M. Callewaert, Wouter Vervecken, Vladimir Kaigorodov