Abstract: A cooling system (1) for use in a non-invasive medical cooling process to cool at least one portion of the body of a person (2) by means of a cooling fluid flowing through a cooling pad (3), comprising a first pump 70, a fluid outlet conduit (20), a fluid inlet conduit (40 and; —a second pump (80) arranged to pump cooling fluid through a fluid bypass conduit (60) from the fluid inlet conduit (40) to the fluid outlet conduit (20), wherein—the cooling system (1) is arranged such that cooling fluid is transported from the tank (10) to the fluid outlet conduit (20) when the first pump (70) is operated and such that cooling fluid is transported from the fluid inlet conduit (40) to the fluid outlet conduit when the second pump (80) is operated.

Abstract: This invention relates to various methods and systems of using therapeutic hypothermia to treat medical conditions such as cardiac arrest, myocardial ischemia, cerebral ischemia, ischemia, stroke, traumatic brain or spinal cord injuries and hypoxic-ischemic injury.

Abstract: Methods are provided herein for affecting a region of a subject's body, comprising exposing the region to a cooling element under conditions effective to cool subcutaneous adipose tissue in said region; and increasing the blood flow rate to the cooled tissue by exposing the tissue to an energy source. Methods are also provided for treating subcutaneous adipose tissue in a region of a subject's body, comprising exposing said region to a cooling element under conditions effective to cool said tissue; and exposing the tissue to an energy source to increase the blood flow rate to the cooled tissue, thereby stimulating reperfusion in, and/or causing an ischemia-reperfusion injury to, the cooled tissue.

Abstract: Eye masks and associated processes are disclosed herein. These masks and associated processes may involve positioning a mask over the eyes and nearby glands of a user and applying heat and/or moisture. This treatment may provide therapeutic benefits, including therapy of Meibomian gland disease and other sources of dry eye. Other physical benefits can also include mechanically gently holding eyelids closed and promoting relaxation and reduction of stress.

Abstract: Disclosed is an eye mask adapted to cover the eyes and the eyelids of a user. The mask includes a main body including an electrical heater and a battery configured to supply the electrical heater and a removable member removably linked to the main body. The removable member includes a wall forming a reservoir provided with retaining orifices adapted to retain a liquid, in particular water, under the effect of the surface tension between the liquid and walls of the orifices. Also disclosed is a method of using such a mask.

Abstract: A heat exchanging pack comprises a substance receiving portion, a first strap receiving portion disposed adjacent a first side of the substance receiving portion, a second strap receiving portion disposed adjacent a second side of the substance receiving portion, and a strap configured for releasably coupling the heat exchanging pack to a portion of a body. The strap includes a first portion extending through the first strap receiving portion, a second portion extending between the first strap receiving portion and the second strap receiving portion, a third portion extending through the second strap receiving portion, and a fourth portion extending out from the first strap receiving portion. The second portion and the fourth portion of the strap are configured to extend at least partially around a portion of a user in need of treatment to releasably couple the heat exchanging pack to the portion of the user.

Abstract: A mouthpiece having particular suitability for cooling oral tissue of a patient undergoing chemotherapy or other medical treatments in which reducing oral cavity temperature is beneficial. The mouthpiece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth, preferably sufficient to reduce capillary blood flow to the patient's mouth. In one embodiment, an external chamber extends from the front of the mouthpiece to house a cooling medium. A bladder is positioned inside the external chamber for storing a solution having a freezing temperature above the freezing point temperature of the cooling medium to assist in cooling the cooling medium. At least one breathing tube extends through the external chamber to permit a patient to breathe through the mouth when the mouthpiece is emplaced within the mouth in the operative close-fitting relationship.

Abstract: An electrosurgical instrument capable of supporting resonance of microwave energy at multiple frequencies. The instrument comprises a coaxial cable and a radiating distal tip portion arranged to receive microwave energy from the coaxial cable. The radiating tip portion consists of a dielectric material having an electrical length selected in conjunction with its dielectric properties at three or more frequencies of microwave energy to support resonance at each frequency. By providing a single device that can effectively couple microwave energy into biological tissue at three or more frequencies, tissue ablation can be performed rapidly with accuracy. The instrument may be used in an apparatus that includes a generator arranged to supply microwave energy at three or more different frequencies.

Abstract: A device for treatment of acne includes: a case having a contact surface portion to contact a skin of an acne region, the contact surface portion being provided with at least one through hole; at least one needle inserted into the skin of the acne region through the through hole with the contact surface portion arranged in contact with the skin; a driving unit arranged inside the case; a needle fixing part arranged inside the case so as to fix the at least one needle and configured to be linearly moved by the driving unit; and a needle cooling unit configured to cooling the at least one needle to transfer coldness into the skin of the acne region through the at least one needle to suppress a function of a sebaceous gland in the skin of the acne region such that proliferation of propionibacterium acnes is limited.

Abstract: A fluid delivery line (FDL) for use in transporting a targeted temperature management (TTM) fluid between a TTM module and a thermal contact pad is disclosed. The FDL can include a bi-luminal fluid conduit and a bi-luminal proximal FDL connector. The two lumens of the proximal connector can be concentrically arranged. An authentication tag attached to the FDL can provide authentication data to a TTM module. A TTM system can include a connection adapter added to an existing TTM module where the adapter includes the electro-mechanical valves. An adapter controller operates the valves in accordance with obtained authentication data from the tag. Fluid connection systems can include valves that automatically open and close upon connection and disconnection. Fluid conduits and connectors can include concentrically arranged fluid lumens.

Abstract: The invention is directed to a mouth piece for cooling of oral tissue of a patient during chemotherapy treatment. The mouth piece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth sufficient to reduce capillary blood flow to the patient's mouth.

Abstract: Implantable thermal therapy devices, systems, and methods are provided for the treatment of pathological conditions including arrhythmias and trauma. The implantable thermal therapy devices and systems are specifically structured to deliver transient cooling to a target tissue, and to gradually dissipate the heat energy transferred from the target tissue to other body masses in a controlled and delicate manner. In some examples, a phase change material can be used to accomplish such a gradual dissipation of the heat.

Abstract: A device and method for treatment of hot flashes in perimenopausal and menopausal women. The device includes a cooling agent distributed over at least a portion of an area of the device, at least one liner positioned against and attached to at least one side of the cooling agent over at least the portion of the area of the device, and an adhesive. The adhesive is arranged on at least one side of the device so as to permit the device to be secured with respect to the anatomy of a user.

Abstract: An apparatus and method for providing hyperthermia therapy to a living subject, in particular a human, animal or plant. The apparatus has contains a signal generator, a signal modulator and an emitter to enable the apparatus to provide hyperthermia treatment. Hyperthermia therapy may be provided to a living subject by generating a signal, selectably modulating the signal and delivering the signal to the target location on the living subject. It is possible to interrupt any further use of the apparatus after a predetermined period.

Abstract: Embodiments of the invention include a method and a device for increasing blood flow and controlling the temperature of a mammal by applying a desired pressure to extremities of a mammal. The device generally includes a pliant body element that is adapted to receive a portion of an extremity of the mammal therein, and then apply a pressure to a portion of the extremity when a pressure is provided to a region in which the extremity is positioned within the pliant body element. By evacuating the region in which the extremity is enclosed, a contact surface area between the extremity of a mammal and the pliant body element is increased, due to the external atmospheric pressure acting on the pliant body element against the skin of the extremity of the mammal. The application of pressure assures that sufficient contact and thermal heat transfer (heating or cooling) is provided to the extremity of the mammal.

Abstract: The present disclosure is for a therapeutic thermal pack configured to conform to three dimensional surfaces. The therapeutic thermal pack comprises first and second plastic sheets bound together forming a sack. The sack further comprises a plurality of joint lines forming open or closed cells within the boundary of the sack. The open and closed cells are configured to enhance the flexibility of the sack. The sack contains a flowable thermal material within the open or closed cells.

Abstract: The invention is directed to a mouth piece for cooling of oral tissue of a patient during chemotherapy treatment. The mouth piece includes a cooling medium contained within the top element and the bottom element and able to retain a cooling environment within the mouth sufficient to reduce capillary blood flow to the patient's mouth. In one embodiment, an external chamber extends from the front of the mouth piece to house a cooling medium. A bladder is positioned inside the external chamber for storing a solution having a freezing temperature above the freezing point temperature of the cooling medium to assist in cooling the cooling medium.

Abstract: The present invention relates to an adhesive sheet for cooling which preferably maintains a cooling effect utilizing the heat of vaporization of water and can exert a persistent high cooling effect. The adhesive sheet for cooling a hydrous polymer gel (A) and a fiber sheet (B) laminated thereon: the hydrous polymer gel (A) having a moisture content of 65% by mass or more and 95% by mass or less, the fiber sheet (B) having a thickness of 0.001 mm or more and 1 mm or less, a basis weight of 3 g/m2 or more and 70 g/m2 or less, and a water absorbency test value of from 1 to 16,000 seconds; wherein the adhesive sheet has an amount of moisture of 585 g/m2 or more and 1,700 g/m2 or less.

Abstract: A thermal pack comprising one or more sacks, a body of thermal material enclosed in the sacks, and first and a second sack edge joined to form a seam line wherein the first edge and the second edge have intersecting directions with an angle that is less than 180 degrees whereby the one or more sacks conforms to a three-dimensional surface.

Abstract: Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like.