Abstract: A gait aid is to be disposed on a shoe, and includes a detecting module, a control circuit and a projecting module. The detecting module generates a sense output based on pressure exerted on a sole of the shoe. The control circuit generates a control signal based at least on the sense output generated by the detecting module. The projecting module is electrically coupled to the control circuit for receiving the control signal therefrom, and is operable, based on the control signal, to project or not to project a cueing mark.

Abstract: The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid.

Abstract: A system and method for characterising a narrowing in a fluid filled tube, the system comprising: a probe having a first measurement sensor to take an instantaneous measurement at different locations along the tube; a mechanism to draw the probe through the tube; a position measure to provide location data relating to the location at which a respective instantaneous measurement is taken by the first measurement sensor; a processor to calculate, from the instantaneous measurements, a characteristic of the tube at different locations along the tube.

Abstract: Neural activity in the brain arising from a stimulus is monitored. A stimulus is applied to a target structure of the brain and a neural measurement is obtained from at least one electrode implanted in contact with the target structure. The neural measurement is configured to capture a measure of any late response arising in the target structure, typically being a neural response arising after conclusion of an ECAP, such as in the period 1.5-10 ms after stimulus onset. The late response(s) can be a useful biomarker such as of therapeutic ranges of deep brain stimulation, disease progression, medication efficacy, and intra-operative changes.

Abstract: An information processing system, computer readable storage medium, and methods for analyzing the airflow related health of a person. A method includes obtaining an audio sample of a person's verbal communication, obtaining geographic information of the person, querying a remote server based on the geographic information, and obtaining additional information from the remote server, the additional information being related to the geographic information, and extracting contours of amplitude change from the at least one audio sample over a period of time, the contours of amplitude change corresponding to changes in an airflow profile of the person. The method further includes correlating the contours of amplitude change with periodic episodes typical of airflow related health problems, and determining, based at least on the additional information, whether the contours of amplitude change result from at least one local environmental factor related to the geographic information.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.

Abstract: A portable unit for metabolic analysis includes a manifold in fluid communication with a mouth of a test subject. A conduit extends from the manifold and defines a flow channel through which the breaths of the test subject travels. A carbon dioxide sensor is attached to the conduit. The carbon dioxide sensor includes an intermediate support housing enclosing a volume disposed along the flow channel to define a first part of the flow channel, an inner support housing attached to a first side of the intermediate support housing, a plurality of IR LEDs mounted to an interior surface of the inner support housing, an outer support housing attached to a second side of the intermediate support housing, and a photodetector attached to the outer support housing. The photodetector faces the flow channel and receives IR radiation emitted by the plurality of LEDs.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed. In some instances, a method of evaluating a vessel of a patient includes moving a second instrument longitudinally through a vessel of the patient from a first position to a second position while maintaining a first instrument in a fixed longitudinal position with respect to the vessel; obtaining pressure measurements from the first and second instruments while the second instrument is moved longitudinally through the vessel; visually depicting the vessel on a display based on the obtained pressure measurements; and modifying the visual depiction of the vessel to simulate one or more treatment options. Systems for performing such methods are also provided.

Abstract: A medical device includes an acoustic transducer, which is configured to sense infrasonic waves emitted from a body of a living subject with a periodicity determined by a periodic physiological activity and to output an electrical signal in response to the sensed waves. At least one speaker is configured to output audible sounds in response to an electrical input. Processing circuitry is configured to process the electrical signal so as to generate a frequency-stretched signal in which infrasonic frequency components of the electrical input are shifted to audible frequencies while preserving the periodicity of the periodic physiological activity in the frequency-stretched signal, and to input the frequency-stretched signal to the at least one speaker.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.

Abstract: An oxygen sensor (1, 2, 3, 4, 5) comprises a working electrode (WE) and a comparatively larger Ag/AgCl reference electrode (RE). A floating voltage between the electrodes (WE, RE) is temporarily retained and a measurement voltage is applied to between the electrodes (WE, RE) during a first period to cause reduction of oxygen and production of an evoked current at the working electrode (WE). The temporarily retained floating voltage is then applied between the electrodes (WE, RE) during a second period to produce a current out from the working electrode (WE). The pO2 in a liquid medium is then representative of a measured net charge to the working electrode (WE) equal to a sum of a charge transferred to the working electrode (WE) during at least a last part of the first period and a charge transferred to the working electrode (WE) during at least a last part of the second period.

Abstract: A system for measuring central venous pressure is provided comprising a device for measuring jugular venous pressure in communication with a patient inclination controller via a processing unit.

Abstract: The present invention relates to an arrangement for taking a biopsy in a human or animal tissue, comprising an elongated hollow member having a circular cross-section in a plane perpendicular to a longitudinal axis, and a circular cutting edge at distal end. The circular cutting edge is provided with at least one cutting slit, running from the cutting edge in a proximal direction of the elongated hollow member. The arrangement further comprises a rotational member configured to apply rotational movement to the hollow member, wherein the rotational movement is applied in accordance to a rotational procedure such that the hollow member is rotated in one direction a predefined amount of rotations, and thereafter rotated in an opposite direction the same amount of rotations.

Abstract: Example biosensor devices having wake-up batteries and associated methods are disclosed. One example device includes a biosensor that has a first electrode for insertion into a subcutaneous layer beneath a patient's skin, and a second electrode coupled to the first electrode for insertion into the subcutaneous layer, and a first battery to apply a voltage across the first and second electrodes, the first battery at least partially electrically decoupled from the electrodes. The device also includes a second battery having an anode material coupled to the first electrode for insertion into the subcutaneous layer, and a portion of the second electrode. The second battery is activatable upon immersion in an electrolytic fluid. The device also includes a wake-up circuit to receive a signal from the second battery and, in response, to electrically couple the first battery to the first and second electrodes to activate the biosensor.

Abstract: The invention aims at downsizing a sensor node incorporating a biosensor to detect biological information and at improving the accuracy of detection made by the biosensor and ensures a quality of communication performed by the sensor node. In the sensor node, a sensor section with a pulse wave sensor formed therein and a main body section with a data processing unit and a wireless communication unit formed therein are separated. The sensor section includes an A/D converter unit that converts an analog signal corresponding to biological information detected by the pulse wave sensor to a digital signal. Digital signal transmission is performed from the A/D converter unit to the data processing unit. Moreover, in the sensor node, there is no conductive member that planarly overlaps with an antenna.

Abstract: A microneedle array device includes a substrate and an array of microneedles on the substrate. Each microneedle includes a redox enzyme and redox mediator and an electrically conductive layer on the substrate. The electrically conductive layer may extend partway up each microneedle exposing the tip thereof.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.

Abstract: The present invention relates to a method for self-collecting intravaginal sample for HPV test. The self-collecting intravaginal sample apparatus of the present invention comprises: an open end part, a closed end part, a tube providing an inner space that a finger could enter to insert an apparatus into women's vagina, a collecting part collecting intravaginal sample and attached outer surface of the closed end of the tube, and a turner preventing the collecting part being contaminated from an outer contaminant; wherein the collecting part collects a sample from the vagina by turning over the tube inside out so that collecting part may place inside of the tube.

Abstract: Provided herein are biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided including electronic devices useful for establishing in situ conformal contact with a tissue in a biological environment. The invention includes implantable electronic devices and devices administered to the surfaces(s) of a target tissue, for example, for obtaining electrophysiology data from a tissue such as cardiac, brain tissue or skin.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to assess the severity of a stenosis in the coronary arteries without the administration of a hyperemic agent.