Abstract: The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on cardiac activity in the subject during the sleep session. Cardiac activity, as monitored via one or more sensors worn on an extremity of the subject and/or placed at a distance from the subject, is used to determine periods of slow wave sleep. Sensory stimulation is delivered to the subject during the periods of slow wave sleep to enhance slow wave activity. Wearing a sensor on an extremity, and/or placing a sensor at a distance from the subject during sleep, as opposed to the subject wearing an EEG cap, is more comfortable for the subject.

Abstract: A device is provided for applying pressure on a vaginal wall of a female subject, said device being configured for insertion into a vaginal cavity of said female subject. The device includes a first deformable element, a second deformable element and a transmission element. The first deformable element has a resting-state and at least one deformed state and is configured for undergoing deformation in response to an inner body pressure. When in the resting state, the first deformable element is configured to anchor the device inside the vaginal cavity. The second deformable element has a resting-state and at least one deformed state, and is configured for undergoing deformation to apply a second pressure on the vaginal wall, such second pressure being operable to narrow a urethral portion the female subject.

Abstract: An ophthalmic radiation device having a substantially light-transparent wand configured to emit light propagating through the wand light from a series of illumination ports at least partially circumscribing a radioactive source disposed in the holder, thereby providing a visual reference for identifying a position of the radioactive source.

Abstract: A medical tube is disclosed, which can include a main body in which a distal portion of a tubular proximal separable piece is detachably connected to a proximal portion of a tubular distal separable piece; and a state maintaining mechanism for maintaining a connected state of the distal separable piece and the proximal separable piece. In addition, the main body is inserted into a body starting from the distal separable piece side, and is disposed inside the body in a state in which a distal end and a proximal end thereof are exposed outside of the body. In addition, the state maintaining mechanism can include a string which is disposed inside the main body and interlocks the distal separable piece and the proximal separable piece, and the connected state can be released by cutting the string.

Abstract: A radiation therapy apparatus includes: an annular gantry; an irradiation unit which is provided on the gantry and configured to radiate radiation; a support which supports the gantry; a rotation-driving mechanism which is provided between the gantry and the support and rotates the gantry around a horizontal central axis of the gantry. The rotation-driving mechanism includes: annular rails that are provided on the gantry; and sliding members which are provided on regions of the support that correspond to a lower half of the gantry, slidably guide the rails, and receive at least a load of the gantry in a vertical direction.

Abstract: The invention relates to a data processing method of determining a radiotherapy treatment plan for radiotherapy treatment of a treatment body part (P) of a patient's body, the method being executed by a computer and comprising the following steps: a) acquiring treatment target position data comprising treatment target position information describing the position of a treatment target (TT1, . . .

Abstract: A tissue anchor system includes a support, a suture inserted through the support, an anchor having a fin forming an eyelet, where the suture is engaged with the eyelet of the fin. An introducer is provided having a cannula defining a bore sized to receive the anchor and a slot formed in a wall of the cannula, with the slot sized to receive the fin of the anchor.

Abstract: Systems that integrate electrocardiography (ECG) functions and Transcranial Magnetic Stimulation (TMS) functions, as well as methods of manufacturing such systems and methods of performing ECG and TMS using such systems, are provided. A system can include a hardware component and a software component in operable communication with the hardware component. The hardware component can include or be in operable communication with a TMS machine, and the software component can be configured to receive waveforms from ECG hardware.

Abstract: Implants for the treatment of pelvic support conditions and methods of implementing the same. The implants comprise relatively soft, flexible bodies and relatively strong arms extending in predetermined orientations therefrom. Methods and devices for placing the implants minimize trauma to the pelvic floor and provide well-anchored support to pelvic organs without interfering with sexual or other bodily functions.

Abstract: The present disclosure pertains to a system and method for managing a sleep session of a subject. Managing the sleep session is based on slow wave activity in the subject during the sleep session. Slow wave activity is related to sleep pressure. Sleep pressure dissipates and/or decreases as the subject sleeps. The dissipation dynamics depend on a given subject. The manner in which dissipation occurs regulates the length of the given sleep session and is linked to the temporal dynamics of slow wave activity. The system is configured to determine a metric indicating sleep pressure dissipation and, responsive to the determined sleep pressure dissipation metric indicating that sleep pressure dissipation has reached a dissipation threshold level during the sleep session, wake the subject.

Abstract: A method and a system are provided for subjecting organic cells in a region of a subject to an extremely low frequency magnetic field. At least one resonance medium is operably connected to a generator. The generator produces a sinusoidal non-harmonic current signal, having a predetermined frequency of substantially between 7.5 Hz and 7.9 Hz. The resonance medium is energized by the signal and the magnetic field yielded is substantially between 0.7 mT and 3 mT to be located adjacent organic cellular tissue in the region for a predetermined period. Organic cells in the laboratory, repository or in the region are subjected to a constant magnetic field of less than 1 mT and having a frequency of substantially between 7.5 Hz and 7.9 Hz for the predetermined period.

Abstract: A radiation therapy planning system (10) includes an isodose line unit (36), a region of interest unit (52), and an optimization unit (58). The isodose line unit (36) receives isodose lines planned for a volume of a subject. The region of interest unit (52) defines at least one isodose region of interest based on the received isodose lines. The optimization unit (58) generates an optimized radiation therapy plan based on the at least one defined isodose region of interest and at least one dose objective for the defined region of interest.

Abstract: Brachytherapy oncology treatment systems and methods are provided. One such system and method employs a catheter or tandem and a mobile balloon device having an enclosed inner volume and an internal surface with an internal perimeter size larger than the external surface perimeter size and adequate to allow sliding longitudinal movement between the catheter or tandem and the mobile balloon device. The mobile balloon device has a radiation dose delivery tube that is at or moves by inflation to a strategic radiation dose delivery location for brachytherapy. An embodiment allows for a multi-part catheter or tandem having a detachable distal section suitable for retaining within a body cavity such as the uterus, both during radiation treatment and during recovery time between radiation treatments. This distal portion can be intended for single-patient use and be disposed of after completion of a radiation treatment session having multiple radiation dose treatment times.

Abstract: A medical cabin system comprises a safety protection structure, an identification structure, an environment simulation structure, a radiotherapy isolation structure, and one or more other independent walls. The safety protection structure is disposed on an entrance of the medical cabin system. The identification structure is disposed on a medical equipment of the medical cabin system or in an enclosed space defined by a stereo location region of the medical cabin system. The environment simulation structure is disposed on a top portion and at least one side wall of the medical cabin system. The radiotherapy isolation structure isolates the stereo location region from a radiotherapy region of the medical cabin system. The independent walls define at least one enclosed space with the radiotherapy isolation structure.

Abstract: A medical assembly and method for the delivery of an implant inside a patient's body. The medical assembly includes an implant, a tubular member, and a delivery device. The tubular member includes a proximal portion defining a first locking feature. The delivery device includes a needle having a proximal portion and a handle having a proximal portion and a distal portion coupled to the proximal portion of the needle. The distal portion of the handle also includes a locking member that defines an opening, the opening being configured to allow at least a portion of the tubular member to pass through the locking member when the locking member is in an unlocked configuration and the locking member configured to engage the first locking feature of the tubular member to prevent the tubular member from being removed from the locking member when the locking member is in a locked configuration.

Abstract: A mount for being releasably received on a medical apparatus and for accommodating a device adapted for insertion inside the mount includes at least two side parts including a first side part and a second side part, at least the second side part or at least a portion thereof being configured so as to pass from a first position into a second position as a result of operational arrangement of the mount on the medical apparatus and/or by operational insertion of the device into the mount. In addition, a medical apparatus includes a like mount.

Abstract: Provided are multi-segmented inflatable brachytherapy devices. Also provided are systems and methods including multi-segmented inflatable brachytherapy devices.

Abstract: Systems are delineated for treating urinary incontinence (UI). More generally, systems are delineated for providing medical treatment, wherein such systems include means for attaching a structure to a patient and removing the structure without damage to the structure or the patient. An exemplary system for providing medical treatment comprises a structure for attachment to a patient utilizing at least one retractable barb.

Abstract: A method and apparatus for treatment of chronic kidney disease (CKD), particular diabetic nephropathy, are disclosed. The method comprises activation of adenosine A2a receptors in parenchymal and immune cells infiltrated into kidneys. The activation is performed by PEMF (pulsed electromagnetic field) stimulation applied locally to kidneys. Adenosine A2a signaling pathway is a potent anti-inflammatory and immuno-suppressive regulator that has been proven to attenuate inflammation and injury in diabetic nephropathy. Efficient activation of A2a receptors is achieved by applying electromagnetic field stimulation consecutively in 3 spatial dimensions. This allows attaining a significant increase in activation of A2a receptors in comparison with one-dimensional stimulation. Assistant thermal stimulation may be applied to increase expression of heat shock proteins (HSPs) in parenchymal cells.

Abstract: A surgical tool adapted for placement of a cuff of an artificial urinary sphincter around a portion of a urethra includes a head attached to a handle. The head has a recess formed in a first end surface of the head and two pads. The recess is sized to receive an inferior portion of the urethra. A first pad is located on a first side of the recess, and a second pad is located on a second side of the recess and spaced a gap distance away from the first pad. A piercing mechanism is located in and movable out of one of the first pad or the second pad. The piercing mechanism is movable across the gap distance between the first pad and the second pad to form a channel in tissue superior to the urethra.