Abstract: An apparatus having a pump reservoir and one or more microcatheters, for use in delivering and/or recovering fluid to and/or from a tissue site or for performing tissue engineering outside of the body. The apparatus can be used in a method to perform site specific microtherapy, including for the treatment of avascular necrosis, compartment syndrome, cerebral edema, and to improve skin flap survival in the course of reconstructive surgery.

Abstract: A balloon dilatation catheter having a catheter shaft with an oblong transverse cross-section with one transverse dimension in a first direction being significantly larger than a second transverse dimension in a direction perpendicular to the first direction. The first dimension is about 1.1 to about 3 times greater, preferably about 1.2 to about 2.5 times greater than the second dimension. In one embodiment, a length of the distal shaft section has inner and outer tubular members where about 30% to not more than about 90% of the inner periphery of the outer tubular member takes the shape of and is secured to the exterior of the inner tubular member. In another embodiment the flexible distal shaft section is an extruded section having an oval or elliptical transverse cross-section. Preferably a pseudoelastic hypotube of NiTi alloy defines at least part of the inflation lumen within the catheter shaft.

Abstract: A steerable direct myocardial revascularization catheter comprises a catheter body, a tip section and a control handle. The catheter body has an outer wall, proximal and distal ends and at least one lumen extending therethrough. The tip section comprises flexible tubing having proximal and distal ends and at least one lumen therethrough. The proximal end of the tip section is fixedly attached to the distal end of the catheter body. The control handle comprises a first member fixedly attached to the proximal end of the catheter body, a second member being movable relative to the first member, and a first guide tube extending through the control handle from the proximal end to the distal end of the control handle. The first guide tube is fixedly attached to one of the first or second members. The catheter also comprises an optic fiber having a distal end and a proximal end.

Abstract: A catheter introducer is disclosed having a splittable introducer and an introducer needle. The splittable introducer includes a pair of wings and a tray with an open top extending from the proximal end of the introducer cannula between the wings to lead the distal end of a long, thin and flexible medical device into the open proximal end of the splittable introducer cannula.

Abstract: A device for alternate sterile connection of a peritoneal catheter, permanently attached to a patient, to a drain tube and to a feed tube for a dialysis liquid, which apparatus comprises a shell in which a first chamber, a second chamber and a connection channel between said chambers are formed and filled with a disinfecting liquid. The chambers include respective couplings for releasable and repeatable coupling the peritoneal catheter and the drain or feed tube with the chambers in conditions of full immersion in the disinfecting liquid. This arrangement makes a tight sterile connection between said catheter and, alternately, said drain and feed tubes via said connection channel.

Abstract: The present invention comprises homeopathic dilutions of growth factors and methods for their use. Disorders which may be effectively treated with the compositions of the present invention include chronic viral disorders, such as HIV, AIDS, chronic fatigue syndrome and Epstein-Barr viral infections, cancer, diabetes and depression. Homeopathic dilutions of growth factors are preferably administered orally. In an alternative embodiment, patients are treated with radio frequency signals corresponding to homeopathic dilutions of growth factors.

Abstract: An inner cannula for a tracheostomy tube assembly is formed from a tubular member having two parallel rows of slots formed along its length and covered by a sheath of thin flexible material on the inside of the tubular member, so that the slots can freely open and close on flexing. The two rows of slots are separated from one another by two longitudinal regions uninterrupted by slots, which give the cannula axial rigidity.

Abstract: A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the cross-sectional area of these paths, the present system is able to be compactly utilized in even the smaller size blood vessels. The catheter system itself is provided with occlusive devices to form an emboli containment chamber in which irrigation and aspiration occur. The catheter system of the present invention provides an improved emboli containment and removal system which can be utilized in a wide range of vessel diameters. The system is easy to use and can quickly and efficiently evacuate the containment chamber.

Abstract: A medical dye delivery system includes a medical dye container and a syringe for withdrawing the medical dye from the container and delivering the dye to a patient. A valve is disposed in the system having an inlet in flow communication with the medical dye container and an outlet in flow communication with the syringe. The valve includes a housing defining a flotation chamber with a valve seat and a flotation member disposed therein. The flotation member seals off the valve seat opening upon medical dye depletion, forcing any remaining fluid flow through a bypass channel that provides restricted flow to provide a tactile warning to the operator of the system that the medical dye container is depleted, yet allow the operator to purge remaining dye from the system.

Abstract: An automatic needle retraction device includes a housing and retraction device for completely retracting a needle back into the housing after use. A selector switch device includes an equalization part, which produces a negative pressure to accept the fluid compressed during the retraction of the hollow needle. Thus, during retraction of the needle, compressed injection solution is not sprayed outward from the needle.

Abstract: A catheter handle including a handle body defining a longitudinally extending handle aperture, a connector adapted to connect a steering wire to the handle body, a piston located at least partially within the handle aperture and slidable relative to the handle aperture, the piston being adapted to be operably connected to a catheter body, and a biasing element, operably connected to the piston, to bias the piston in the distal direction. As an alternative to the biasing element, or in addition, the catheter handle may also include a steering wire anchor associated with the handle body and including a movable portion operably connected to the proximal portion of the steering wire.

Abstract: A balloon dilatation catheter having a catheter shaft with an oblong transverse cross-section with one transverse dimension in a first direction being significantly larger than a second transverse dimension in a direction perpendicular to the first direction. The first dimension is about 1.1 to about 3 times greater, preferably about 1.2 to about 2.5 times greater than the second dimension. In one embodiment, a length of the distal shaft section has inner and outer tubular members where about 30% to not more than about 90% of the inner periphery of the outer tubular member takes the shape of and is secured to the exterior of the inner tubular member. In another embodiment the flexible distal shaft section is an extruded section having an oval or elliptical transverse cross-section. Preferably a pseudoelastic hypotube of NiTi alloy defines at least part of the inflation lumen within the catheter shaft.

Abstract: An apparatus for visually indicating fluid flow through a fluid system or apparatus such as a medical infusion device. The apparatus comprises a pair of thin, indicia bearing films disposed in an overlaying relationship. These films are shifted relative to each other by movement of mechanical actuators which are deflected solely by the pressure of the fluid within the fluid conduits of the system of the apparatus. The two films are stacked in closed proximity and are preferably constructed from a substantially transparent flexible material such as mylar. One surface of the inferior film is printed with a plurality of integrated symbols depicting various fluid flow conditions. The superior film functions as a mask over the inferior film and is printed with a pattern of diagonally extending, alternating clear and opaque stripes. The print ratio of the superior film permits viewing at any one time of only one of the symbols printed on the inferior film.

Abstract: A needleless syringe capable of accelerating particles comprising a therapeutic agent across skin or mucosal tissue of a vertebrate subject is provided. The syringe comprises an elongate tubular nozzle having a bend along its length and is connected to or capable of connection to a suitable energizing means for producing in the nozzle a supersonic condition sufficient to cause delivery of the particles to a target surface. A method for delivering particles comprising a therapeutic agent from the needleless syringe is also provided.

Abstract: The invention provides a handheld, manually operable fluid applicator, particularly suited to the needs of surgeons, which can dispense multiple medically useful fluids, for example fibrin and thrombin components of a tissue adhesive, and which has a smooth feel and action. The applicator has a novel actuator mechanism providing a comparatively higher mechanical advantage in a commencement phase of the actuator stroke and a comparatively lower mechanical advantage in a completion phase of the actuator stroke.

Abstract: A drainage catheter system including a catheter, a collection bag, and a collection bag saddle, is provided. The catheter includes a catheter body having an interior lumen, an elongate tubular sheath operatively associated with the catheter body, and a layer of lubricant disposed between the catheter body and the tubular sheath. The sheath is inflatable after deployment to provide sealing engagement with an inner wall of the urethra. One end of the catheter body is adapted to be connected to the collection bag which includes a fluid entry portion having a one-way fluid valve, a gas separation chamber, and a one-way gas valve. The collection bag also includes a main liquid reservoir in fluid communication with the fluid entry portion and a sealed drainage member for permitting drainage of the main liquid reservoir.

Abstract: A catheter assembly for draining and collecting fluid from a body cavity has a container having an inner containment space defined therewith. An elongate tubular catheter extends longitudinally through the container. A tip member/lubricant reservoir is mounted to the catheter passage opening. A quantity of lubricant is disposed within a tip member/lubricant reservoir and lubricate the catheter as it is extended from the container.

Abstract: A device for dosing medicinal fluids, in particular a feeding solution for enteral alimentation, has a pump unit (2) with a displacement element (15) and a drive unit (3) for the displacement element. The pump unit (2) can be separated from the drive unit (3) and is realized in the form of a non-reusable, disposable item. After the device has been used, the pump unit is simply replaced with a new pump unit, so that it is unnecessary to clean the parts of the dosing device that carry the fluid.

Abstract: The invention relates to an apparatus for injecting the body of humans or animals with a pharmaceutical preparation, wherein the preparation is arranged in a rigid carrier, wherein the apparatus comprises: a chamber into which the carrier can be transported; and a channel connecting onto the chamber for transporting the carrier into the body comprising fixation means for fixing the end of the channel relative to the skin of the body for injecting in order to prevent a movement of the channel in the direction perpendicularly of the axis of the barrel. According to one embodiment the fixation means are formed by chamfered protrusions formed on the part adapted for contact with the skin of the body and extending substantially in the direction of the axis of the channel.

Abstract: A system of rotate-to-advance medical devices including catheters, dilators, occluders, stents, suprapubic catheters and camera introducers configured with external screw threads and depending substantially on rotation for means of advancement and emplacement in mammalian genitourinary and gastrointestinal passages and organs.