Abstract: A method of forming particles comprises accelerating a stream comprising a liquid; and vibrating the stream, to form particles. The particle may have a diameter that is smaller than the diameter of the nozzle used to form the stream, allowing for the formation of micro- and nano-sized particle.
Type:
Grant
Filed:
July 21, 2003
Date of Patent:
May 6, 2008
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
Kyekyoon Kim, Daniel W. Pack, Cory Berkland
Abstract: The present invention includes a drug release system. The drug release system comprises a bulk polymer phase and a polymeric drug-enriched phase within the bulk polymer phase. At least one drug is incorporated into the drug-enriched phase.
Abstract: Emulsions suitable for use in cosmetic and pharmaceutical compositions are disclosed. Various substrates for body care, such as wipes and pads, are disclosed, which substrates are impregnated with the emulsions. Such treated substrates are suitable for use, for example, in body care, sun protection, antiperspirant and insect repellent formulations. A process for cold temperature production of the emulsions is also disclosed.
Abstract: For clinical application of cis[((1R,2R)-1,2-cyclohexanediamine-N,N?)bis(R1)]platinum(II) (R1 is an alkanoyloxy group having 6 to 20 carbon atoms), the present invention aims at providing a formulation which prevents layer separation and changes in viscosity, shows fine suspendability, and which is easy to handle during administration. The formulation of the present invention is a lyophilized formulation for injection obtained by dissolving a cis[((1R,2R)-1,2-cyclohexanediamine-N,N?)bis(R1)]platinum(II) in 2-methyl-2-propanol and lyophilizing this solution, which has a central particle size distribution of around 3-25 ?m and a D90% value of not more than 40 ?m.
Abstract: Compositions which can be applied to body hairs or head hair, comprising an aqueous suspension of magnetic latex microspheres and of colloidal nanoparticles of magnetic pigment.
Abstract: A particulate composition comprises from 40 to 80% by weight of a water-soluble saccharide, from 1.5 to 10% by weight of a finely particulate amorphous hydrophobic silica having a surface area in the range of from 80 to 300 m2/g and water. The composition is in the form of fine particles of an aqueous solution of the water-soluble saccharide, the surfaces of which fine particles of aqueous solution are coated with a coating of the finely particulate amorphous hydrophic silica. The composition, which may additionally contain one or more biocidally-active materials, can be applied through conventional dust applicator equipment for the treatment of pests.
Abstract: Biodegradable invasive medical device, in particular for guided tissue regeneration, which device comprises a biodegradable polymer, composed of a thermoplastic and/or thermosetting polymer admixed to a solvent that is miscible with any aqueous and/or aqueous alcoholic and/or alcohol-group-containing solution and/or with physiological liquids, whether of a synthetic or natural type. The said water-insoluble thermoplastic and/or thermosetting polymer and the water-miscible solvent for the polymer and mixed together in such a proportion as to form an organogel or a plastigel or a xerogel, or a solid-containing pasty product of the slurry type.
Abstract: The present invention relates to a surface-modified nanoscale zinc oxide, where the surface modification involves coating with an oligo- or polyethylene glycol acid. This surface-modified zinc oxide is characterized in that it forms stable dispersions in a liquid medium. In addition, the present invention relates to a process for the production of surface-modified zinc oxide, and also to a process for the production of nanoscale zinc oxide dispersions.
Type:
Grant
Filed:
June 21, 2004
Date of Patent:
March 25, 2008
Assignee:
Henkel Kommanditgesellschaft auf Aktien
Inventors:
Rainer Kliss, Ralf Elsässer, Melita Heller, Christian Umbreit, Horst Hahn, Christian Kropf, Mete Berber, Victor Bulto Carulla
Abstract: The use of inorganic nanoparticles to stabilize aqueous hydrogen peroxide solutions is described. The preferred nanoparticles are formed from clays. The use of nanoparticles formed from synthetic smectite clays is particularly preferred. The stabilized hydrogen peroxide solutions may be utilized for various purposes, but are particularly useful as contact lens disinfecting solutions.
Type:
Grant
Filed:
November 16, 2004
Date of Patent:
March 18, 2008
Assignee:
Alcon, Inc.
Inventors:
Howard Allen Ketelson, Nathaniel D. McQueen
Abstract: A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body that is manufactured at a first manufacturing facility; and a dosage form coupled to the body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dosage form is manufactured at a second manufacturing facility. Also, a method for producing a medicated tampon including manufacturing a tampon body at a first manufacturing facility; manufacturing a dosage form at a second manufacturing facility, wherein the dosage form includes a formulation including a therapeutic agent; and coupling the dosage form to the tampon body.
Abstract: A color cosmetic composition containing color impregnated spherules where the color is expressed from the spherule upon application of the cosmetic to the keratinous surface and the expressed spherule serves an uptake function on the keratinous surface; a cosmetic composition containing a rupturable spherule filled with color, and a method for color skin using such compositions.
Type:
Grant
Filed:
October 13, 2005
Date of Patent:
March 11, 2008
Assignee:
Revlon Consumer Products Corporation
Inventors:
Julio Gans Russ, Ida Marie Sandewicz, Tatyana Zamyatin, Merry Lee Nickl
Abstract: A polysaccharide selected from xanthan gum and HPMC is used for the treatment or prophylaxis of IBD, especially Crohn's Disease, left-sided ulcerative colitis or pouchitis.
Type:
Grant
Filed:
September 25, 1998
Date of Patent:
March 11, 2008
Inventors:
Jean-Pierre Sachetto, William Jeffery Sandborn, William John Tremaine
Abstract: A personal care composition that includes a personal care ingredient and semiconductor nanocrystals. A method of protecting at least a portion of a body against ultraviolet radiation by applying a personal care composition is also provided.
Abstract: A tampon adapted to deliver a therapeutic agent, the tampon including a tampon body having a distal end; and a dosage form affixed to the distal end of the tampon body, wherein the dosage form includes a formulation including a therapeutic agent, and wherein the dosage form comprises a plurality of layers. Also, a method for manufacturing a medicated tampon adapted to deliver a therapeutic agent, the method including manufacturing a tampon body having a distal end; producing a dosage form having a plurality of layers, wherein the dosage form includes a formulation including a therapeutic agent; and affixing the dosage form to the distal end of the tampon body.
Type:
Grant
Filed:
December 31, 2002
Date of Patent:
March 11, 2008
Assignee:
Kimberly-Clark Worldwide, Inc.
Inventors:
Steven Craig Gehling, Donald C. Harrison, James H. Liu, Wolfgang A. Ritschel, Chris Clendening, Giovanni M. Pauletti
Abstract: The present invention concerns an extended release formulation having an accelerating erosion and/or dissolution rate of the surface of the formulation. The formulation comprises a drug having low solubility in water dispersed or dissolved in at least one erasable hydrophilic polymeric matrix.
Type:
Grant
Filed:
January 15, 2003
Date of Patent:
March 4, 2008
Assignee:
Watson Pharmaceuticals, Inc.
Inventors:
Inger Nordén, Catarina Carling, Peter Fyhr
Abstract: This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The novel formulation includes at least one pharmacologically active ingredient, and a solvent system having a monoalkylether of diethylene glycol and a glycol present in specified ratios, and a mixture of water and alcohol. The invention also relates to a method for inhibiting or delaying crystallization of an active agent in a pharmaceutical formulation.
Type:
Grant
Filed:
March 7, 2006
Date of Patent:
February 26, 2008
Assignee:
Antares Pharma IPL AG
Inventors:
R. Dario Norberto Carrara, Arnaud Grenier, Celine Besse
Abstract: The invention relates to a styling composition comprising, in a physiologically acceptable liquid medium, the combination of at least one film-forming fixing polymer and of at least one crystalline hot-melt polymer which is soluble in the said medium and which has a crystalline melting temperature, measured by differential scanning calorimetry, of between 30° C. and 80° C., and to a process for the thermal remodelling of the hair using this composition.
Abstract: A pharmaceutical composition comprising: (a) an anticholinergic of formula 1 ?wherein X? is an anion with a single negative charge; and (b) a compound of formula 2 ?or the pharmacologically acceptable acid addition salts, solvates, and hydrates thereof.
Abstract: A transdermal therapeutic system (TTS) with a content of at least one active substance from the group of the carboxyl group-containing non-steroidal antirheumatics, which has a backing layer (1), an active substance-containing matrix layer (2) and a detachable protective layer (3), is characterized by a matrix layer (2) based on a carboxyl group-containing polyacrylate pressure-sensitive adhesive, which matrix layer (2) has a content of oleic acid and potassium ions, with the constituent amount of the potassium ions being in the range of from 5 to 50%, relative to the equivalent weight of the sum of all carboxyl group-containing matrix components.