Abstract: Disclosed is a DNA analysis method and a DNA analyzer whose signal intensity is not lowered even when a material at a higher density is measured. There is supplied dATP, dTTP, dGTP, or dCTP from a dATP solution vessel, a dTTP solution vessel, a dGTP solution vessel, or a dCTP solution vessel, and this causes an extension reaction of a double-stranded DNA immobilized to a bead, to yield pyrophosphoric acid. The pyrophosphoric acid is converted into a redox compound by the actions of a reagent and an enzyme contained in a reaction buffer in a reaction buffer vessel. The redox compound causes a variation in surface potential of a measuring electrode bearing an electrochemically active material immobilized thereto through an insulating molecule, and this variation causes a variation in drain current of a field-effect transistor electrically connected to the measuring electrode. Thus, the extension reaction is detected.

Abstract: The invention relates to a method of labelling and analysing nucleic acids. More specifically, the invention relates to a method of analysing nucleic acids, which comprises contacting the nucleic acids to be detected, which are in the form of single-stranded nucleic acid strands partially (i.e. over a part of the total length of the nucleic acid strands) hybridized with protective strands, with substances which specifically react with nucleobases of the single-stranded sections of the nucleic acid strands, and which are capable of subsequently participating in a reversible redox reaction in electroanalytical processes known to the skilled worker.

Abstract: A system and method for the high temperature in-situ determination of corrosion characteristics of a molten metal on an alloy under study is provided which takes place within an insulated furnace. A graphite crucible provided in the furnace contains an electrolyte formed from a molten salt of a metal halide. A reference electrode formed from the same metal as the electrolyte is immersed in the electrolyte solution in the graphite crucible. A beta-alumina crucible containing a molten metal is also provided within the furnace and preferably within the graphite crucible. A measuring electrode formed from the alloy under study is immersed in the molten metal. Standard electrochemical techniques are used to measure and analyze the electrochemical effects of corrosion of the molten metal on the alloy.

Abstract: A gas sensing element is disclosed as having a measuring gas chamber to which measuring gases are admitted, a diffusion resistance portion for introducing measuring gases to the measuring gas chamber under diffusion resistance, a sensor cell for detecting a specified gas concentration of measuring gases, and an oxygen pump cell for adjusting an oxygen concentration in the measuring gases. The sensor cell includes a measuring electrode, placed facing the measuring gas chamber, and a reference electrode formed in pair with the measuring electrode. The oxygen pump cell includes an inner pump electrode placed facing the measuring gas chamber, and an outer pump electrode formed in pair with the inner pump electrode. The diffusion resistance portion is placed in an area inside of external end walls of the inner pump electrode to be exposed to the measuring gas chamber.

Abstract: A gas sensor for detecting particles in a gas stream has a first electrochemical pump cell, which has a measuring chamber in which a first electrode is disposed to pump particles between the first measuring chamber and the gas stream. Furthermore, a second electrochemical pump cell is provided, which has a second measuring chamber in which a second electrode is disposed so as to pump particles. The second measuring chamber is connected to the gas stream via an absorber medium for absorption of the particles to be detected. This makes it possible to absorb the particles to be detected in a first operating mode using the absorber medium, and to desorb the absorbed particles in a second operating mode, and to detect the quantity of the desorbed particles. Thus, the gas sensor is able to take even low concentrations into account, and short-term measuring errors do not have such a serious effect.

Abstract: It is an object of this invention to measure small amounts of a plurality of sample solutions at the same time. The small amounts of sample solutions are respectively placed on measuring electrodes, a medium is placed across the plurality of sample solutions, a liquid joint of a reference electrode is brought into contact with the medium, and a potential difference between each of the measuring electrodes and the reference electrode via the medium is measured.

Abstract: An electrochemical gas sensor testing device that includes a test signal generator that generates a multiplexed signal that includes a first test signal that includes alternating current (AC) and is free from a direct current (DC) component and a second signal that includes a DC bias voltage, an electrochemical cell that includes a counter electrode, a sensing electrode, and an electrolyte, the counter electrode and the sensing electrode being in electrical communication with the electrolyte and each other, the counter electrode being in electrical communication with the signal generator to receive the multiplexed signal generated by the signal generator, and a processor that receives an AC signal from the sensing electrode and that analyzes the AC signal.

Abstract: The present invention is directed to a reversible electrochemical sensor for polyions. The sensor uses active extraction and ion stripping, which are controlled electrochemically. Spontaneous polyion extraction is suppressed by using membranes containing highly lipophilic electrolytes that possess no ion-exchange properties. Reversible extraction of polyions is induced by constant current pulse of fixed duration applied across the membrane. Subsequently, polyions are removed by applying a constant stripping potential. The sensors provide excellent stability and reversibility and allow for measurements of heparin concentration in whole blood samples via protamine titration. The sensors can also monitor a polyion concentration and an enzyme activity, wherein the polyion decomposition is directly proportional to the enzyme activity in a sample. Additionally, the sensors can monitor an enzyme inhibitor activity.

Abstract: An electrochemical cell for testing the electrochemical behavior of a plurality of materials comprises: a first electrode; a counter-electrode bearing an electrochromic material having a visual or measurable property which changes in a manner proportional to the total charge passed through it; and an electrolyte between and in electrical contact with the first electrode and the counter-electrode; wherein one of the first electrode and the electrolyte comprises a plurality of regions, each region comprising a sample of material to be tested, the regions being, in the case of the first electrode, electrically connected to a common terminal. Such a cell can be used for a “combinatorial chemistry” approach to testing the properties of possible cell components.

Abstract: Methods and devices are provided for improved environmental protection for photovoltaic devices and assemblies. In one embodiment, the device comprises of an individually encapsulated solar cell, wherein the encapsulated solar cell includes at least one protective layer coupled to at least one surface of the solar cell. The protective layer has a chemical composition that prevents moisture from entering the solar cell and wherein light passes through the protective layer to reach an absorber layer in the solar cell.

Abstract: An exhaust gas sensor inhibits a detecting part of an exhaust gas sensor from being exposed to water and has high detection accuracy and high durability. The exhaust gas sensor has a sensor body and a protective cover. The sensor body has an outer housing. The outer housing has a plurality of gas inlets. A gas detection element for detecting a component of the exhaust gas (e.g., oxygen) disposed within the outer housing. The protective cover has a cylindrical shape and has a plurality of protrusions at its opposing ends. The protrusions provide a tight fit with the outer housing. The protective cover is attached to the outer periphery of the outer housing without closing gas inlets formed through the outer cylinder by press-fitting the outer cylinder into the protective cover.

Abstract: An electrochemical sensor strip has a base and a first electrode and a second electrode on the base. An oxidoreductase enzyme and a mediator are on the first electrode, and a soluble redox species is on the second electrode. The soluble redox species may be an organotransition metal complex, a transition metal coordination complex, an electroactive organic molecule, or mixtures thereof.

Abstract: A fuel cell sensor is provided for detecting the presence of acetylene and hydrogen in a fluid. The sensor includes a sensing element having first and second gas diffusing electrodes spaced from one another. The first gas diffusing electrode can be used for sensing acetylene. The second gas diffusing electrode can be used for sensing hydrogen. A fuel cell spacer having an acidic electrolyte is disposed between the sensing element and a common electrode. The sensing element can be configured to have a specific ratio of the area between the first gas diffusing electrode in relation to the area of the second gas diffusing electrode.

Abstract: Methods and apparatus for the micro-scale, dielectrophoretic separation of particles are provided. Fluid suspensions of particles are sorted and separated by dielectrophoretic separation chambers that have at least two consecutive, electrically coupled planar electrodes separated by a gap in a fluid flow channel. The gap distance as well as applied potential can be used to control the dielectrophoretic forces generated. Using consecutive, electrically coupled electrodes rather than electrically coupled opposing electrodes facilitates higher flow volumes and rates. The methods and apparatus can be used, for example, to sort living, damaged, diseased, and/or dead cells and functionalized or ligand-bound polymer beads for subsequent identification and/or analysis.

Abstract: An electrochemical sensor is provided that exhibits improved adhesion of the membrane to the nitride layer used as an insulating layer in silicon- or silicon-oxide-based electrochemical sensing devices. The sensing devices include a substrate, an oxide disposed on the substrate, a nitride disposed on the oxide, an electrically conductive structure disposed on the oxide layer, and an electrode disposed on the oxide layer and electrically coupled to the electrically conductive structure. At least one opening is formed in the nitride layer to form at least one adhesion trench that exposes a surface region of an oxide layer underlying the nitride layer. The membrane covers the electrode, and contacts the oxide surface regions exposed by the adhesion trenches. The contact between the membrane and the oxide surface region provides for improved adhesion of the membrane to the electrochemical sensing device.

Abstract: Disclosed is a DNA analysis method and a DNA analyzer whose signal intensity is not lowered even when a material at a higher density is measured. There is supplied dATP, dTTP, dGTP, or dCTP from a dATP solution vessel, a dTTP solution vessel, a dGTP solution vessel, or a dCTP solution vessel, and this causes an extension reaction of a double-stranded DNA immobilized to a bead, to yield pyrophosphoric acid. The pyrophosphoric acid is converted into a redox compound by the actions of a reagent and an enzyme contained in a reaction buffer in a reaction buffer vessel. The redox compound causes a variation in surface potential of a measuring electrode bearing an electrochemically active material immobilized thereto through an insulating molecule, and this variation causes a variation in drain current of a field-effect transistor electrically connected to the measuring electrode. Thus, the extension reaction is detected.

Abstract: An apparatus and methods for solar conversion using nanoscale cometal structures are disclosed herein. The cometal structures may be coaxial and coplanar. A nanoscale optics apparatus for use as a solar cell comprises a plurality of nanoscale cometal structures each including a photovoltaic material located between a first electrical conductor and a second electrical conductor. A method of fabricating solar cells comprises preparing a plurality of nanoscale planar structures; coating a plurality of planar surfaces of the plurality of planar structures with a photovoltaic semiconductor while leaving space between the plurality of planar surfaces; and coating the photovoltaic semiconductor with an outer electrical conductor layer, wherein a portion of the outer electrical conductor layer is located between the planar structures to form coplanar structures.

Abstract: The invention described herein generally pertains to utilization of high power density microwave energy to reduce organic compounds to carbon and their constituents, primarily in a gaseous state. The process includes, but is not limited to, scrap tires, plastics, asphalt roofing shingles, computer waste, medical waste, municipal solid waste, construction waste, shale oil, and PCB/PAH/HCB-laden materials. The process includes the steps of feeding organic material into a microwave applicator and exposing the material to microwave energy fed from at least two linear polarized sources in non-parallel alignment to each other, and collecting the material. The at least two sources of microwave energy are from a bifurcated waveguide assembly, whose outputs are perpendicular to each other and fed through waveguide of proper impedance, such that the microwave sources are physically and electrically 90° out of phase to each other. The microwave frequency is between 894 and 1000 MHz, preferably approximately 915 MHz.

Abstract: A biosensor strip having a low profile for reducing the volume of liquid sample needed to perform an assay. In one embodiment, the biosensor strip includes an electrode support; an electrode arrangement on the electrode support; a cover; a sample chamber; and an incompressible element placed between the cover and the electrode support, the incompressible element providing an opening in at least one side or in the distal end of the sample chamber to provide at least one vent in the sample chamber. In another embodiment, the biosensor strip has an electrode support; an electrode arrangement on the electrode support; a cover; and a sample chamber, the cover having a plurality of openings formed therein, at least one of the openings in register with the sample chamber. The invention further includes methods for preparing such a biosensor strips in a continuous manner.

Abstract: An electrochemical sensor is provided that includes a housing having an outer wall, an axial bore circumscribed by the outer wall, and a barrier wall that aids in defining a reference cavity. The housing further including a plurality of cross members in spaced relation to one another disposed between the axial bore and the outer wall, each cross member defining an aperture. A junction plug is disposed at the distal end of the housing. The junction plug comprises a porous material that enables ionic flow through the junction plug. The sensor enables ionic communication between the target fluid and the reference electrode within the reference cavity through the apertures of the plurality of cross members. In this manner, the sensor provides generally a long, tortuous flow path, or salt bridge, between the target fluid and the reference electrode, resulting in a high resistance factor for the sensor.