Abstract: This document describes systems and methods for treating and recovering water from feed solutions using a membrane module that has a plurality of hollow fiber membranes encapsulated in a collection chamber and an expansion chamber that is connected to the outlet of the membrane module.
Abstract: The present invention refers to new species of an ion exchange adsorber which is suitable for the separation of host cell proteins (HCPs), antibody fragments and low molecular weight substances from solutions containing antibodies. The invention especially refers to a process for purifying biological samples by separating biomolecules of interest and impurities, comprising steps of contacting a sample with said chromatography media consisting of fibers, said fibers having imparted thereon functionality enabling ion exchange chromatography and/or hydrophobic interaction.
Abstract: The present invention relates to a crosslinked unreinforced cellulose hydrate membrane crosslinked using at least two different crosslinking agents, to a method for the production thereof and to the use of the crosslinked unreinforced cellulose hydrate membrane according to the invention.
Type:
Grant
Filed:
December 1, 2017
Date of Patent:
January 18, 2022
Assignee:
Sartorius Stedim Biotech GmbH
Inventors:
Sandra Van Der Kruijs, Annette Reiche, Gabriel Nino-Amézquita, Louis Villain, Hans-Heinrich Hörl, Dieter Melzner, Franziska Bäthe
Abstract: The present application discloses novel systems for conducting the filtration of blood using manifolds. The manifolds integrate various sensors and have fluid pathways formed therein to direct fluids from various sources through the requisite blood filtration or ultrafiltration system steps.
Type:
Grant
Filed:
June 18, 2018
Date of Patent:
January 18, 2022
Assignee:
Fresenius Medical Care Holdings, Inc.
Inventors:
Barry Neil Fulkerson, Russell T. Joseph
Abstract: The present disclosure provides systems for refrigeration facility cooling and water desalination. In certain aspects, the systems include a refrigeration facility having a water cooling subsystem configured to receive cool water and output warm water and a desalination plant co-located with the refrigeration facility and configured to receive and desalinate the warm water. Aspects of the invention also include methods for cooling a refrigeration facility using a water cooling subsystem and desalinating water with a desalination plant that is co-located with the refrigeration facility.
Abstract: An assembly comprises a manifold configured to couple to a medical fluid cassette and a multi-lumen tube comprising a plurality of lumens within an outer wall of the multi-lumen tube. The manifold has a plurality of fluid connection ports and can be connected to the multi-lumen tube (e.g., via an adapter).
Abstract: Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.
Type:
Grant
Filed:
February 28, 2019
Date of Patent:
December 28, 2021
Assignee:
NxStage Medical, Inc.
Inventors:
Mark T. Wyeth, Gregory Yantz, Robert Paul McCarty
Abstract: A turbocharger includes a turbocharger housing having an impeller housing comprising a circular cross-section. A main nozzle is disposed within the turbocharger housing communicating a first portion of a fluid stream to a first volute. A first auxiliary channel and a first auxiliary nozzle communicating a second portion of the fluid stream to the first volute. The first auxiliary nozzle is downstream of the main nozzle. A second auxiliary channel and a second auxiliary nozzle communicate a third portion of the fluid stream to the first volute. The second auxiliary nozzle is downstream of the first auxiliary nozzle. A valve assembly is selectively coupling the first auxiliary channel to the first auxiliary nozzle and the second auxiliary channel to the second auxiliary nozzle.
Type:
Grant
Filed:
April 19, 2021
Date of Patent:
December 21, 2021
Assignee:
Fluid Equipment Development Company, LLC
Abstract: A chemical liquid manufacturing apparatus, including a first system and a second system, is provided. The first system includes at least one first filtration medium, selected from a first filter, a first ion exchange membrane and a first ion adsorption membrane, wherein the first system is configured to process a material of at least one time. The second system includes at least one second filtration medium, selected from a second filter, a second ion exchange membrane and a second ion adsorption membrane, wherein the second system is configured for recirculation and to process the material of at least two times.
Type:
Grant
Filed:
March 29, 2019
Date of Patent:
December 14, 2021
Assignee:
FUJIFILM Electronic Materials U.S.A., Inc.
Inventors:
Bryan Hinzie, Marcia Cole-Yocom, Michael Barker, Perry Westberg, Yuan Chen, Jack Helzer
Abstract: The present technology relates to control systems for use with fluid treatment systems. In one embodiment, for example, a fluid treatment system includes a vessel configured to receive a fluid having one or more constituents and to separate one or more constituents from the fluid. The system can also include a tube extending along at least a portion of the vessel and a sensor. The tube can be in fluid communication with a pressurized air source, and the sensor can be configured to obtain a measurement of an operating parameter. The system can also include a controller in communication with the sensor and pressurized air source. The controller can execute one or more algorithms to determine a filter parameter based on the measurement of the operating parameter, compare the filter parameter to a threshold, and, based on the comparison, activate or deactivate the pressurized air source.
Type:
Grant
Filed:
November 21, 2016
Date of Patent:
December 14, 2021
Assignee:
NEXOM (US), INC.
Inventors:
Cornelius J. Strain, Ryan Coe, Miguel A. Gutierrez
Abstract: The present invention relates to a method of fabricating an organic structure directing agent-free CHA type zeolite membrane and a membrane fabricated thereby, and more particularly to a method of fabricating a continuous CHA type zeolite membrane, which exhibits CO2/N2 and CO2/CH4 separation performances comparable with those of conventional membranes, in a cost-effective manner without a calcination process by hydrothermal synthesis using an alkali metal hydroxide without using an organic structure directing agent, and to a membrane fabricated thereby.
Type:
Grant
Filed:
July 31, 2018
Date of Patent:
December 14, 2021
Assignee:
Korea University Research and Business Foundation
Inventors:
Jungkyu Choi, Kwan-Young Lee, Eunhee Jang
Abstract: A desalination system includes a feed pump having an inlet side and an outlet side. In addition, the system includes a first RO stage having an inlet, RO permeate outlet and RO concentrate outlet. Further, the system includes a second RO stage having an inlet, RO permeate outlet and RO concentrate outlet and an NF stage having an inlet, NF permeate outlet and an NF concentrate outlet. The system also includes a set of conduits adapted to connect: (a) the outlet side of the feed pump to the inlet of the first RO stage; (b) the concentrate outlet of the first RO stage to (i) the inlet of the second RO stage and to the inlet of the NF stage; and (c) the permeate outlet of the first RO stage, the permeate outlet of the second RO stage and the permeate outlet of the NF stage either directly or indirectly to a low salinity water injection line.
Type:
Grant
Filed:
March 26, 2018
Date of Patent:
November 30, 2021
Assignee:
BP EXPLORATION OPERATING COMPANY LIMITED
Abstract: A surface-modified filter membrane for filtering blood, in particular for separating blood plasma and blood serum, and a method for the production thereof, a filter provided therewith and the use thereof.
Type:
Grant
Filed:
July 16, 2018
Date of Patent:
November 30, 2021
Assignee:
BOEHRINGER INGELHEIM VETMEDICA GMBH
Inventors:
Christoph Weber, Heinz Schoeder, Jens Altrichter, Roland Kirchner, Stefan Margraf, Michael Scholl
Abstract: The present invention relates to systems and methods for filtration and/or dilution of fluids, in particular for the dialysis of blood. The systems comprise a filter device (10) having a fluid chamber (18) and comprising a first lid (20) having arranged thereon a first fluid port (22). The filter device (10) further comprises a second lid (30) having arranged thereon at least a second fluid port (32). The filter device (10) further comprises a plurality of hollow fibers (40) arranged within the housing (12), wherein each of the plurality of hollow fibers (40) comprises a semi-permeable membrane and defines a fluid channel extending longitudinally through an interior of the respective hollow fiber (40). Also, the filter device (10) comprises a fourth fluid port (50) and a fifth fluid port (52) both provided at the fluid chamber (18).
Type:
Grant
Filed:
June 14, 2018
Date of Patent:
November 23, 2021
Assignee:
GAMBRO LUNDIA AB
Inventors:
Olof Jansson, Bjoern Ericson, Henrik Hall
Abstract: Many processes generate wastewater streams rich in sulfate and chloride. These salt components are traditionally not recovered and are discharged to the environment. The invention recovers pure water for recycle/reuse and simultaneously generates valuable pure salts of NaCl and Na2SO4 for beneficial reuse, eliminating the waste stream. Process consists of the sequential crystallization of salt products with an intermediate purification step in which a chemical reactant is added to elevate levels of purity. The process is configured to simultaneously achieve zero liquid discharge.
Type:
Grant
Filed:
December 3, 2018
Date of Patent:
November 23, 2021
Assignee:
AQUATECH INTERNATIONAL, LLC
Inventors:
Daniel P. Bjorklund, Vinod A. Raje, James M. Marlett, Manish Backliwal, Richard Schoen, Gregory Mandigo
Abstract: A sample purification system includes a container assembly bounding a sample purification compartment and having an upper end and an opposing lower end, the sample purification compartment comprising mixing zones and settling zones. A plurality of shielding elements are positioned within the sample purification compartment so as to at least partially separate adjacent mixing zones and settling zones or separate adjacent mixing zones, the mixing zones being in fluid communication with the settling zones. A mixing element is disposed within each mixing zone. An acoustic wave settler is aligned with a portion of the container assembly, the acoustic wave settler being configured to emit an acoustic wave through the portion of the container assembly and a mixture disposed therein, the acoustic wave coalescing fluid phase droplets disposed in the mixture to increase the buoyancy or density of the fluid phase droplets.
Type:
Grant
Filed:
March 16, 2020
Date of Patent:
November 16, 2021
Assignee:
Life Technologies Corporation
Inventors:
Scott P. Collins, Christopher D. Brau, Nephi D. Jones
Abstract: A method for processing a blood sample is provided that can improve the recovery rate of deformable rare cells that would easily pass through a filter and small rare cells while reducing the filtration area of the filter, and that can recover the rare cells alive.
Abstract: A composite liquid filtration platform including a composite filtration medium featuring an electrospun polymeric nanofiber layer collected on a porous membrane. When in use, the porous membrane acts as a prefilter used upstream from the polymeric nanofiber layer to remove particles from a liquid stream flowing through the composite filtration structure. The nanofiber layer, positioned downstream from the porous membrane, is used as the retentive layer for critical filtration to provide biosafety assurance, and is responsible for capturing microorganisms like bacteria, mycoplasma or viruses. The composite liquid filtration platform provided herein exhibits permeability advantages over conventional porous membranes or nanofiber mats spun on coarse non-wovens.
Type:
Grant
Filed:
March 30, 2012
Date of Patent:
October 26, 2021
Assignee:
EMD Millipore Corporation
Inventors:
Onur Y. Kas, Mikhail Kozlov, Gabriel Tkacik, David Nhiem, Philip Goddard, Sherry A. Leon
Abstract: Thin film composite membrane with nano-sized bubbles having enhanced membrane permeability, preparation methods and uses thereof are provided. The method of preparation of a thin film composite membrane, comprising: a) an aqueous solution containing at least an amine, and b) an organic solution containing at least a polyfunctional acyl halide, an additive or soluble gas being present in a) and/or b), or a nano-bubble generator or ultrasound are used to generate nano-bubbles in a) and/or b). Interfacial polymerization of a) and b) occurs at or near the surface of a porous support membrane. The advantage of creating nano-sized bubbles in the separating layer of membrane is that it can reduce membrane resistance without sacrificing the mechanical strength and stability of the membrane so as to improve its water permeability, salt rejection and antifouling. In addition, the process is simple to adopt while performance improvement of the membrane is remarkable.