Abstract: A surgical access device includes a cannula assembly and an obturator. The obturator is configured to removably couple with the cannula assembly along a central axis of the cannula assembly to facility inversion of the surgical access device through a body wall of the patient. The obturator includes an elongated shaft extending along a longitudinal axis, a tapered distal tip located at a distal portion of the elongated shaft, and an obturator head located at a proximal portion of the elongated shaft. The obturator head includes an interference fit feature capable of inhibiting proximal movement between the obturator and the cannula assembly via a frictional force against a surface of the cannula assembly.

Abstract: In one aspect the present disclosure refers to a supplementary device for a manually operable injection device, the supplementary device comprising: a body attachable to an elongated housing of the injection device, at least one connector connected to the body and connectable to the housing, wherein the body is attachable to the housing via the at least one connector, a sensor arrangement coupled to at least one of the body and the at least one connector and configured to measure a longitudinal force component acting between the at least one connector and the body in a direction parallel to the elongation of the housing.

Abstract: A system for controlling a hemostasis valve includes a hemostasis valve having a body portion having a proximal end, a distal end and a lumen extending between the proximal end and the distal end. The hemostasis value further includes at least one valve positioned in the proximal end of the body portion and an engagement member operatively coupled to the at least one valve. The system further includes a first drive member coupled to the engagement member and a controller coupled to the first drive member. The controller is configured to control the first drive member to impart movement to the engagement member to open and close the at least one valve.

Abstract: A receptacle includes an elongate barrel section defining a barrel length between an axial position pA and an axial position pB; side walls each having an inner surface bordering an interior; a layer of a lubricant located on the inner surface; and a charge present in the interior and sealing a cross section of the interior between the inner surfaces of the side walls. An axial position p+ is the axial position closest to pB at which the charge contacts the layer or the inner surfaces and an axial position p? is the axial position closest to pA at which the charge contacts the layer or the inner surfaces. The distance between pB and p+ divided by the distance between p+ and pA is in a range from 0 to 2 and a mean thickness of the layer between pA and p. is at least 10 nm.

Abstract: The invention relates to a puncturing system comprising an outer tubular body which is designed to remain in a body part of a living being, characterized in that the puncturing system has at least one inner tubular body and a puncturing needle, wherein the inner tubular body is guided through a working lumen of the outer tubular body and can be longitudinally displaced with respect to the outer tubular body, and the puncturing needle is guided through a puncture lumen of the inner tubular body and the inner tubular body can be longitudinally displaced with respect to the puncturing needle, wherein, after a body part has been punctured by means of a puncturing section of the puncturing needle, which protrudes out of a patient-side end of the puncturing system, the inner tubular body can be moved out of the patient-side end of the catheter at least partially out of the outer tubular body, and is thereby designed to accommodate the puncturing section of the puncturing needle, which protrudes out of the patient-s

Abstract: An autoinjector includes a case configured to receive a syringe, a slidable member that is movable axially within the case to cause at least a portion of the syringe to move axially when the syringe is disposed within the case for dispensing a medicament through a needle of the syringe, a locking member configured to prevent actuation of the slidable member when the autoinjector is in a pre-dispense configuration, a sleeve coupled to a distal end of the case and surrounding at least a portion of a needle of the syringe when the syringe is disposed within the case, an elongate member extending proximally from the sleeve and configured to deflect the locking member to allow actuation of the plunger, and two drive springs coupled to the slidable member and configured to apply a biasing force that acts on the slidable member to move the slidable member distally.

Abstract: Disclosed herein is an auto injector for administering a medicament, the auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper and a cartridge compartment containing the medicament, the cartridge compartment having a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a processing unit coupled to the drive module, wherein the processing unit is configured to control the drive module to move the plunger rod from a first plunger rod position to a mix plunger rod position with a mix plunger rod speed, wherein the mix plunger rod position is selected to position the first stopper in a position wherein the first medicament component is m

Abstract: Flush syringe assemblies are described herein. Such flush syringe assembly may include a barrel including a side wall defining a chamber, a collar mounted on a distal wall of the barrel and surrounding an elongate tip. A cap may be attached to the collar via a hinge. The flush syringe assembly may also include a cap attached to the collar via a hinge. A ring may be disposed around the collar with a locking element that engages with a corresponding mating locking projection on the cap. The cap may include a slanted surface. The slanted surface of the cap may include one or more ribs made of an elastomeric material.

Abstract: An endoscopic bendable tube includes: an integrally formed resin tube; at least two wires embedded in a tube wall of the resin tube from a proximal end side to a distal end side of the resin tube, the at least two wires being parallel to a tube axis direction of the resin tube and being at positions facing each other; and a plurality of pairs of through slits formed in the tube wall of the resin tube in the tube axis direction, each pair of through slits being formed facing each other in the tube wall of the resin tube.

Abstract: The invention relates to a device for the dosed dispensing of an infusion fluid, in particular for administering an infusion for a patient, comprising a fluid vessel for accommodating the infusion fluid, and comprising an infusion line which is arranged between the fluid vessel and a patient access during the use of the device, wherein the fluid vessel and the infusion line are connected to one another, and the infusion line is designed such that at least a sub-section of the infusion line has a predefined inner diameter and a predefined length, such that the amount of infusion fluid accommodated in the fluid vessel is dispensed to the patient access over a predetermined time period in a manner dependent on a predefined height at which the fluid vessel is arranged above the patient access.

Abstract: A medical system configured to aid a user in locating an access port of an implantable medical device, the medical system including an implantable port comprising a medicament chamber accessible through a septum, a localizer base operably coupled to the implantable port comprising an array of electromagnetic field emitting coils, an antenna array comprising a plurality of electromagnetic field sensing coils, and a user interface adapted to display data received from the antenna array to visually depict a relative position of the antenna array relative to the localizer base.

Abstract: The present disclosure relates to medical delivery devices that include a barrel having an inner surface, and in at least one embodiment, the inner surface is hydrophilic. The medical delivery device may further include a stopper may having an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated to the one or more fluoropolymer layers. In some embodiments, the contact angle of the inner surface of the barrel is less than about 58°. Additionally, the stopper includes a sliding surface that is less than about 2.0 mm. The barrel provides inner surface that in combination with the fluoropolymer laminate or fluoropolymer film achieve high levels of air and liquid impermeability while also maintaining an acceptably low break loose force, low average glide force, and low glide force variation. In some embodiments, the compressibility stopper against the barrel is greater than about 7.9%.

Abstract: Aspiration medical device as well as methods for making and using aspiration medical devices are disclosed. An example aspiration medical device may include a tubular member having a distal end region and defining an inflow orifice adjacent to the distal end region. An aspiration member may be disposed within the tubular member. The aspiration member may have a plurality of axially-spaced fluid jets formed therein.

Abstract: Embodiments of the invention include devices, compositions and methods for the controlled release of therapeutic substances, such as drugs. Control over the rate of release of the therapeutic substances from the devices is achieved by the use of nanoporous membranes in which the pore size is matched to the molecular diameter of the therapeutic substances. Some embodiments of the invention achieve zero-order release by the use of membranes with a pore diameter that is more than five times the Stokes' diameter of the therapeutic substance released.

Abstract: A device includes a processor and a non-transitory memory having processor-executable instructions stored thereon. The device is usable with a blood treatment apparatus, such as a hemodialysis machine. The processor-executable instructions, when executed by the processor, facilitate: determining a time point with regard to puncturing a vessel of a patient, wherein puncturing the vessel of the patient is related to a blood treatment for the patient using a blood treatment apparatus; determining a time period based on the determined time point; and transmitting data related to the determined time point and/or data related to the determined time period to a receiving device.

Abstract: A method for treating a patient using a catheter insertion device. The catheter insertion device includes a housing, a needle, a catheter, a guidewire, and a thumbwheel. The needle extends through the catheter such that a distal end of the needle extends distal of a distal end of the catheter. The guidewire is coupled to the thumbwheel such that rotation of the thumbwheel advances a distal end of the guidewire through a lumen of the needle. The method includes holding the catheter insertion device, inserting the distal end of the needle and catheter into a blood vessel, rotating the thumbwheel to advance the distal end of the guidewire out of the lumen of the needle into the blood vessel, moving the catheter over the guidewire in the blood vessel, and removing the needle and the guidewire from the catheter.

Abstract: A receptacle includes: an elongate barrel section with an axial position p determined along an axis, the elongate barrel section extending from an axial position pA to an axial position pB; a side wall extending over the elongate barrel section and having an inner surface bordering an interior with a diameter; and a layer of a lubricant located on at least a part of the inner surface, a portion of the axis extends from a first axial position p1 to a second axial position p2; a mean thickness of the layer is determined in the portion; a position pm is the midpoint between p1 and p2; TA is a mean thickness of the layer for a section from p1 to pm; TB is a mean thickness of the layer for a section from pm to p2; a ratio TA:TB is in a range from 5:1 to 1:5.

Abstract: A skull-mounted drug and pressure sensor (SOS), a smart pump (ISP) electrically coupled to the SOS and a drug delivery and communications catheter communicating the SOS with the ISP are combined for a first embodiment. A skull-mounted (SOS), a metronomic biofeedback pump (MBP) electrically coupled to the SOS and a drug delivery and communications catheter having a sending and receiving optical fiber communicating the SOS with the MBP are combined for a second embodiment. A third embodiment combines a (SOS), an implantable power and communication unit (PCU) electrically coupled to the SOS, and a drug delivery and communications catheter for communicating the SOS with the PCU and for communicating the exterior source of the drug to the SOS. A fourth embodiment combines a ventricular catheter with a CSF accessible chamber and drug delivery port; and an implantable stand-alone skull-mounted drug and pressure sensor (SPS).

Abstract: A skull-mounted drug and pressure sensor (SOS), a smart pump (ISP) electrically coupled to the SOS and a drug delivery and communications catheter communicating the SOS with the ISP are combined for a first embodiment. A skull-mounted (SOS), a metronomic biofeedback pump (MBP) electrically coupled to the SOS and a drug delivery and communications catheter having a sending and receiving optical fiber communicating the SOS with the MBP are combined for a second embodiment. A third embodiment combines a (SOS), an implantable power and communication unit (PCU) electrically coupled to the SOS, and a drug delivery and communications catheter for communicating the SOS with the PCU and for communicating the exterior source of the drug to the SOS. A fourth embodiment combines a ventricular catheter with a CSF accessible chamber and drug delivery port; and an implantable stand-alone skull-mounted drug and pressure sensor (SPS).

Abstract: Treatment controllers and methods are provided that can be integrated with treatment systems, such as peritoneal dialysis systems, hemodialysis systems, and nocturnal treatment systems, to manage execution of treatment operations or a course of treatment based on timing information and/or patient sleep state.