Patents Examined by Layla Berry
  • Patent number: 9339515
    Abstract: Methods and compositions of the invention relate to the treatment of pulmonary fibrosis.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: May 17, 2016
    Assignee: Galectin Therapeutics, Inc.
    Inventor: Peter G. Traber
  • Patent number: 9333220
    Abstract: Bodily tissue and structures may be protected using a fluid layer containing a mixture of chitosan and oxidized polysaccharide. The mixture forms a protective gel layer via in situ crosslinking. Compared to crosslinking using a low molecular weight aldehyde such as glutaraldehyde or genipin, oxidized polysaccharides appear to provide faster gelation while avoiding the use of potentially less bioacceptable low molecular weight aldehydes.
    Type: Grant
    Filed: November 13, 2013
    Date of Patent: May 10, 2016
    Assignee: Medtronic, Inc.
    Inventors: Edze Jan Tijsma, Maria Nieves Gonzalez, Erica M. TenBroek, Nancy Schaffhausen
  • Patent number: 9320799
    Abstract: An esterified cellulose ether comprises (i) aliphatic monovalent acyl groups or (ii) groups of the formula —C(O)—R—COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation or (iii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein the cellulose ether has anhydroglucose units joined by 1-4 linkages and has methyl groups, hydroxyalkyl groups, and optionally alkyl groups being different from methyl as substituents such that the esterified cellulose ether has an MS (hydroxyalkyl) of 0.05 to 1.00, and hydroxyl groups of anhydroglucose units are substituted with methyl groups such that [s23/s26?0.2*MS(hydroxyalkyl)] is 0.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: April 26, 2016
    Inventors: Robert L. Schmitt, Robert L. Sammler, Meinolf Brackhagen, Oliver Petermann, Roland Adden, Nicholas S. Grasman, Steven J. Guillaudeu
  • Patent number: 9290521
    Abstract: A novel method of simultaneously protecting two functions which are same or different, namely hydroxyl, amine, or thiol ones, particularly in sugars, polyalcohols, nucleosides, nucleotides, peptides, and nucleic acids during an organic synthesis, and to novel compounds for implementing this method, as well as to the method of obtaining these compounds. Method of simultaneously protecting two hydroxyl, amine, or thiol functions according to the invention by carrying out a protecting reaction between a compound having at least two free hydroxyl, amine, or thiol groups, and the disilane of formula 1, where R stands for Cl or Br, or I, or a substituent of formula 2, where X1, X2, X3, X4 are the same or different.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: March 22, 2016
    Assignees: INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK, FUNDACJA UNIWERSYTETU IM. ADAMA MICKIEWICZA W POZNANIU
    Inventors: Wojciech Tadeusz Markiewicz, Marcin Krzysztof Chmielewski, Sylwia Maria Musial, Hieronim Franciszek Maciejewski, Grzegorz Hreczycho
  • Patent number: 9266918
    Abstract: An alkenyl glycoside is prepared by reacting a metathesis-derived unsaturated fatty alcohol containing 10 to 30 carbon atoms with either (1) a reducible monosaccharide or composition hydrolyzable to a reducible monosaccharide, or (2) a hydrocarbyl glycoside produced by reacting an alcohol containing up to 6 carbon atoms with a reducible monosaccharide or composition hydrolyzable to a reducible monosaccharide. Each of these reactions is performed in the presence of an acid catalyst and under conditions sufficient to form the alkenyl glycoside or hydrocarbyl glycoside. The preferred alkenyl glycosides are 9-decen-1-yl glycoside; 9-dodecen-1-yl glycoside; 9-tridecen-1-yl glycoside; 9-pentadecen-1-yl glycoside; 9-octadecen-yl glycoside; or 9-octadecen-1,18-diyl glycoside.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: February 23, 2016
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Ryan A. Littich, Jonathan Brekan, Timothy Montavon