Patents Examined by Len E. Horne
  • Patent number: 4910021
    Abstract: A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and usually, a carrier. The absorption promoter is capable of enhancing absorption of the active ingredient from the intestine into the bloodstream. The capsule is coated with a film forming composition, which film is sufficiently insoluble at a pH below 7 as to be capable of protecting the capsule and its contents from the digestive juices until the capsule reaches a region below the upper part of the intestine, whereupon the coating and capsule are capable of eroding or dissolving to release the active ingredient for absorption into the bloodstream.
    Type: Grant
    Filed: November 25, 1986
    Date of Patent: March 20, 1990
    Assignee: R. P. Scherer Corporation
    Inventors: John D. Davis, Elka Touitou, Ardon Rubinstein