Abstract: A method improves depth of focus in a first eye only by adding a higher order aberration (HOA) to the first eye by adding a monofocal optical device to the first eye. The method may also correct a spherical aberration in a second eye by inserting a monofocal aspheric IOL. The HOA added to the first eye may be selected from the group consisting of spherical, trefoil and coma. Additionally, the monofocal optical device inserted into the first eye may comprise a monofocal aspheric IOL that adds spherical aberration to the first eye. The optical device inserted into the first eye may comprise a 20 D monofocal aspheric IOL that adds 0.4 ?m of spherical aberration to the first eye at 6 mm entrance pupil and adds 0.1 ?m of spherical aberration to the first eye at 4 mm entrance pupil.

Abstract: A flow modifying apparatus may include a plurality of struts coupled together to form a radially expandable frame having a proximal end and a distal end. The proximal and distal ends may be radially expandable into expanded proximal and distal ends. A reduced diameter portion of the expandable frame may be disposed between the expanded proximal and distal ends and the reduced diameter portion may comprise a fluid flow through passage. A cover may be disposed over at least a portion of the radially expandable frame. The reduced diameter portion modifies fluid flow therethrough immediately upon implantation thereof and forms a pressure gradient between the inflow end and the reduced diameter portion.

Abstract: A spacer for creating a docking station for a transcatheter heart valve is provided. The spacer changes an effective diameter and/or a shape of an implanted bioprosthetic structure such as a bioprosthetic heart valve or annuloplasty ring, providing a supporting structure into which the transcatheter valve expands without over expanding. The spacer may be deployed through an interventional technique either through transseptal access, transfemoral access, or transapical access and is typically deployed at least in part on an inflow portion of the implanted bioprosthetic structure.

Abstract: An implantable device for the treatment of hydrocephalus using a stent having a peripheral wall and an interior passageway and wherein a plurality of microneedles project outwardly from the peripheral and each needle includes a microneedle passageway from an aperture adjacent a distal end of the microneedle to a proximal end of the microneedle adjacent the peripheral wall. A corresponding plurality of one-way microvalves is positioned at the proximal ends of the microneedle and wherein the microneedle passageway is in fluid communication with the interior passageway whenever the one-way microvalve is open. When the stent is implanted in the superior sagittal sinus with the distal end of the plurality of microneedles positioned within the subarachnoid space and at least one of the plurality of microvalves is open, the stent permits cerebrospinal fluid to pass from the subarachnoid space to the superior sagittal sinus.

Abstract: According to various aspects and embodiments, a growth adaptive expandable stent is provided. The expandable stent includes a stent structure having a cylindrical shape that is self-expanding in a radial direction and includes a plurality of cylindrical rings disposed along a longitudinal axis of the stent structure. The stent structure is configured to exert a continuous outward radial force over time when implanted such that a diameter of the stent structure expands from a first value to a second value that is at least about 1.5 times the first value.

Abstract: An exemplary method of performing an annuloplasty procedure includes introducing a catheter into a left atrium of a heart, deploying a first member from the catheter, anchoring the first member to a posterior side of a mitral valve annulus in the left atrium, deploying a second member from the catheter, anchoring the second member to an anterior side of the mitral valve annulus in the left atrium, deploying a flexible tensile member from the catheter, attaching the tensile member to both the first member and the second member and applying tension to the tensile member to draw the first member and the second member toward one another and bring the posterior side and the anterior side of the mitral valve annulus into closer approximation. Annuloplasty systems and components are also disclosed.

Abstract: An ophthalmic implant including an IOL with haptics, and drug delivery devices secured to the haptics. The posterior-most extent of the drug delivery device is located anterior to the posterior edge or PCE barrier edge, of the IOL. In other configurations, the drug delivery devices are provided with PCO barrier edges.

Abstract: A vascular shunt frame with improved apposition including a main body tube; at least one end of the main body tube is provided with a sealing covering; the sealing covering is provided with a main blood flow opening; a shaping component is disposed at the edge of the main blood flow opening. When the main body stent is inserted into the main blood flow opening of the main body tube, the shaping component can be closely attached to the outer surface of the main body stent, such that the sealing covering closely fits the outer surface of the main body stent to prevent endoleaks. The present disclosure also provides a vascular stent provided with an apposition-improved vascular shunt frame.

Abstract: There is provided a toric intraocular lens which improves the visibility of a toric axis. The toric intraocular lens is a toric intraocular lens including a lens body provided with an astigmatic axis. A mark indicating the astigmatic axis is formed at an optical surface of an outer rim portion of the lens body, and a length in a radial direction of the lens body and a length in a circumferential direction of the lens body of external dimensions of the mark are different from each other in top view of the optical surface.

Abstract: An intraocular lens, wherein an outer periphery of an optic portion has a peripheral surface, and a radially inner portion of a peripheral portion of the IOL has an inner surface, wherein the peripheral surface is directly adjacent to the inner surface, and wherein the peripheral surface does not directly extend (coupled to or integrally formed therewith) from the inner surface, and wherein the peripheral surface and the inner surface are configured so that the peripheral portion is stabilized in at least one of, and optionally both of, the proximal and distal directions relative to the optic portion.

Abstract: A branched stent includes a main branch having a tubular main lumen and a side branch that branches off from the main branch. The main branch and the side branch are made from a strand-shaped starting material. The side branch is configurable between a first state in which the side branch lies within the main lumen and a second state in which the side lies outside the main lumen. In the second state, the side branch defines a tubular side branch fluidically connected to the main lumen. The side branch is formed at least in part of a shape-memory material.

Abstract: An apparatus has a central lens body for providing vision correction for a patient. The lens body has a central aperture and is configured as one of: a diffractive lens or a refractive lens. The lens body has at least one haptic extending from the lens body, and the central aperture has a form of a circular hole extending fully through the lens body when the apparatus is implanted in the eye. The lens body is formed from a substantially transparent material and the central aperture includes a darkened perimeter. The darkened perimeter of the central aperture includes a darkened internal wall extending through the lens body from an anterior surface to a posterior surface of the lens body.

Abstract: Hybrid Accommodating Intra Ocular Lens (AIOL) assemblages including two discrete component parts in the form of a discrete base member for initial implantation in a vacated capsular bag and a discrete lens unit for subsequent implantation in the vacated capsular bag for anchoring to the discrete base member. The lens unit includes a lens optics having at least two lens haptics radially outwardly extending therefrom. The base member includes a flat circular base member centerpiece having zero optical power.

Abstract: The present disclosure relates generally to stents and methods for managing passage of material through a body lumen. In some embodiments, a medical stent may include a stent body defined by a hollow tubular elongate structure extending along a central axis, the stent body including a first portion and a second portion. The medical stent may further include a control region between the first and second portions, wherein in a first configuration the hollow tubular elongate structure of the control region is in a closed, twisted configuration, and wherein in a second configuration the hollow tubular elongate structure of the control region is in an open, expanded configuration.

Abstract: An articulated prosthesis, left in the patient's heart for repairing a tricuspid or mitral valve, is conceived so as to grip simultaneously all the three leaflets of the tricuspid valve, or the two of the mitral valve, so as to make them lay distended fully in the valve plane and assume a final configuration as in the common surgical procedure. It is also disclosed a related catching device and a device for repairing a tricuspid or mitral valve.

Abstract: An illustrative stent may comprise an elongated tubular member having a longitudinal axis, the elongated tubular member comprising at least one knitted filament forming a plurality of twisted knit stitches with intermediate rung portions extending circumferentially between radially adjacent twisted knit stitches. Each twisted knit stitch may be interconnected with a longitudinally adjacent twisted knit stitch forming a series of linked stitches. The elongated tubular member may be configured to move between a collapsed configuration and an expanded configuration, wherein in the collapsed configuration the series of linked stitches form longitudinal columns and in the expanded configuration the series of linked stitches extend helically around the elongated tubular member.

Abstract: Described herein are radially self-expanding stents. The disclosed stents can be used to widen arteries and/or veins of a patient to counteract or combat narrowing of the arteries and/or veins associated with certain congenital diseases, such as aortic coarctation. As an example, the disclosed stents are configured to be placed at or near a narrowed portion of the aorta where the stent produces a radial outward force on the aorta. The radial force produced by the stent widens the aorta and causes the stent to expand with the aorta. The disclosed stents can be crimped to relatively small sizes for placement in small patients (e.g., less than about 10 kg in size) and can be configured to expand to widen the aorta and to accommodate growth in the patient.

Abstract: Endovascular systems for deployment at branched arteries include a main tubular graft body deployable within a main artery including a proximal end and an opposed distal end. The proximal and distal ends have a tubular graft wall therein between. A plurality of inflatable channels are disposed along the main tubular graft body, and at least one stent segment is disposed along the tubular graft wall of the main tubular graft body. The plurality of inflatable channels are configured to be inflatable with an inflation medium. The at least one stent segment is disposed between two or more adjacent inflatable channels of the plurality of inflatable channels.

Abstract: A valve prosthesis (10), comprising a stent (1), a leaflet (2), and a skirt (3); the stent (1) comprises an inflow end, an outflow end, and a plurality of wavy segments axially connected; the wavy segments comprise a plurality of reticular structure units disposed circumferentially; the leaflet (2) and the skirt (3) are fixed on the stent (1) respectively; the upper portion of the skirt (3) is provided with indentations (321); the skirt (3) is fixed with the leaflet (2) by means of the indentations (321); the skirt (3) further comprises first protrusion portions (323) extending toward the direction of the outflow end of the stent; one ends of the first protrusion portions (323) are connected with the indentations (321), and the other ends of the first protrusion portions are fixed to the stent (1); by such a way, the connection strength of the skirt (3) and the stent (1) is enhanced; and besides, when the valve prosthesis (10) is implanted at a lower position, perivalvular leakage preventing height can be inc

Abstract: An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.