Patents Examined by Lynette F. Smith
  • Patent number: 5904942
    Abstract: A highly digestible, good preference, relatively high-quality fermented formula feed which is obtainable by mixing a soybean feed material and a wheat splinter capable of decomposing phytin in an amount of not less than that of the soybean feed material, d.s.b., and subjecting the mixture to a lactic acid fermentation under humid conditions.
    Type: Grant
    Filed: September 12, 1997
    Date of Patent: May 18, 1999
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Satoshi Iritani, Yoshinori Sato, Hiroto Chaen, Toshio Miyake
  • Patent number: 5902599
    Abstract: Biodegradable polymer networks are provided which are useful in a variety of dental and orthopedic applications. The biodegradable polymer networks can be formed in one embodiment by polymerizing anhydride prepolymers including crosslinkable groups, such as unsaturated moieties. The anhydride prepolymers can be crosslinked, for example in a photopolymerization reaction by irradiation of the prepolymer with light in the presence of a free radical initiator. Suitable anhydride prepolymers include dianhydrides of a dicarboxylic acid and a carboxylic acid molecule comprising a crosslinkable group. For example, methacrylic acid dianhydrides of monomers or oligomers of a diacid such as sebacic acid or 1,3-bis(p-carboxyphenoxy)-hexane can be used. The anhydride prepolymers can be applied in vivo to a site where an orthopedic implant is needed, and then may be crosslinked, for example, by irradiation with U.V. light, to form a biodegradable implant such as a rods, pin or plate.
    Type: Grant
    Filed: February 20, 1996
    Date of Patent: May 11, 1999
    Assignee: Massachusetts Institute of Technology
    Inventors: Kristi S. Anseth, Robert Langer, Venkatram R. Shastri
  • Patent number: 5903101
    Abstract: An organic electroluminescent element ("organic EL element") capable of emitting light with high luminance by driving at a low voltage, and inhibiting deterioration in organic layers is provided. A surface treatment of an indiumtin oxide (ITO) transparent electrode with a titanate coupling agent containing phosphorus in the side chain thereof improves adhesion between the ITO transparent electrode and an organic hole transport layer. As a result, it is possible to increase the efficiency of injection of holes, improve low-voltage driving and luminance, and prevent deterioration in the organic layers.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: May 11, 1999
    Assignee: Sony Corporation
    Inventor: Yasunori Kijima
  • Patent number: 5900525
    Abstract: A value-added composition of matter containing plant matter from transgenic alfalfa which expresses exogenous phytase activity is disclosed. The phytase activity is a gene product of an exogenous gene encoding for phytase which has been stably incorporated into the genome of alfalfa plants. The transgenic alfalfa expresses phytase activity in nutritionally-significant amounts, thereby enabling its use in animal feeds to eliminate the need for phosphorous supplementation of livestock, poultry, and fish feed rations.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: May 4, 1999
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Sandra Austin-Phillips, Richard G. Koegel, Richard J. Straub, Mark Cook
  • Patent number: 5900247
    Abstract: The present invention relates to a new mucoadhesive pharmaceutical composition which makes possible the prolonged release of active pharmaceutical principles in the buccal cavity or via the transmucosal route.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: May 4, 1999
    Assignee: Adir et Compagnie
    Inventors: Isabelle Rault, Gerald Pichon
  • Patent number: 5900261
    Abstract: The invention relates to a new hard crystalline coating based on a specific mixture of polyols. It exhibits, in particular, the characteristic of having an improved crunchiness compared with the coatings known in the prior art. The subject of the invention is also a process for producing this specific coating and an improved process for hard coating based on xylitol, maltitol or lactitol or mixtures thereof.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: May 4, 1999
    Assignee: Roquette Freres
    Inventors: Guillaume Ribadeau-Dumas, Michel Serpelloni
  • Patent number: 5900262
    Abstract: A highly digestible, good preference, relatively high-quality fermented formula feed which is obtainable by mixing a soybean feed material and a wheat splinter capable of decomposing phytin in an amount of not less than that of the soybean feed material, d.s.b., and subjecting the mixture to a lactic acid fermentation under humid conditions.
    Type: Grant
    Filed: September 18, 1996
    Date of Patent: May 4, 1999
    Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
    Inventors: Satoshi Iritani, Yoshinori Sato, Hiroto Chaen, Toshio Miyake
  • Patent number: 5897869
    Abstract: The present application relates to an extruded cosmetic composition, provided in the form of a soft paste, comprising, in a fatty phase, at least one compound having a high melting temperature.The invention also relates to a process for preparing the composition by extrusion.
    Type: Grant
    Filed: June 3, 1996
    Date of Patent: April 27, 1999
    Assignee: L'Oreal
    Inventors: Veronique Roulier, Therese Daubige
  • Patent number: 5897673
    Abstract: Fine metallic particles-containing fibers with various fine metallic particles therein, which have fiber properties to such degree that they can be processed and worked, and which can exhibit various functions of the fine metallic particles, such as antibacterial deodorizing and electroconductive properties are provided, as well as a method for producing the same.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: April 27, 1999
    Assignee: Japan Exlan Company Limited
    Inventors: Ryosuke Nishida, Yoko Yamamoto
  • Patent number: 5897930
    Abstract: A carrier web having at least one surface that is multiple, sequentially embossed, wherein depressions created from the prior embossing patterns(s) are preserved during the subsequent embossing pattern(s) even though the subsequent embossing pattern(s) are superimposed on the depressions from the prior embossing pattern(s). The patterns of embossing can be Euclidean or fractal created from machine tools produced using microreplication and other techniques. The carrier webs are useful for release liners for pressure sensitive adhesives and a number of other industrial and consumer applications.
    Type: Grant
    Filed: December 31, 1996
    Date of Patent: April 27, 1999
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Clyde D. Calhoun, David C. Koskenmaki
  • Patent number: 5895650
    Abstract: The present invention provides a non-infectious immunotherapeutic containing retroviral particles devoid of outer envelope proteins or containing selected antigens isolated from a retrovirus. There is also provided a vaccine effective against HIV. In one aspect, the immunogen is useful for immunizing an individual previously infected by a retrovirus including HIV, so as to induce immunoprotective factors protective against progression of the infection. In another aspect, the vaccine is useful for vaccinating an individual not previously infected with HIV in order to prevent subsequently acquired infection. In another aspect, there is provided a method of rendering a viral immunogen non-infectious. The immunogen may also be used to produce is antibodies for passive immunotherapy, alone or in conjunction with active immunotherapy, in individuals infected with a retrovirus, including HIV, preferably those individuals exhibiting low levels of antibodies to retroviral gene products other than the outer envelope.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 20, 1999
    Assignee: The Immune Response Corporation
    Inventors: Jonas Salk, Dennis J. Carlo
  • Patent number: 5895678
    Abstract: A method and apparatus for applying a material to a substrate. A material application station includes a shutter assembly having at least one horizontally extending blade which is rapidly displaceable from a closed configuration in which an outlet path of the shutter assembly is obstructed to an open configuration in which the outlet path is open. While the blade of the shutter assembly is in the closed configuration, a coating material is applied to a first predetermined area on an upper surface of the shutter assembly. A substrate is located beneath the shutter assembly in the outlet path. The blade of the shutter assembly is rapidly opened so that the coating material falls onto the substrate over a second predetermined area on an upper surface of the substrate. The second predetermined area is substantially equal to the first predetermined area. The resulting deposit is of a controlled diameter.
    Type: Grant
    Filed: January 30, 1997
    Date of Patent: April 20, 1999
    Assignee: Ishida Co., Ltd.
    Inventor: Adrian M. Sunter
  • Patent number: 5891623
    Abstract: The invention provides assays for the presence or absence of CD4+ T cell subpopulations carrying particular V.beta. components of the T cell receptor (TCR-V.beta.) in persons infected with HIV, including amplification of mRNA from T cells with primers specific to each TCR-V.beta. to detect the presence or absence of each TCR-V.beta. in a sample and primers for use in such amplification assays are disclosed. The invention also provides assays of antibody-containing fluids of a person infected with HIV to determine the immunodeficiency where the fluid is suspected to contain an antibody having a paratope specific to an epitope on a TCR-V.beta.. The invention also provides a binding agent specific to a paratope where the paratope is specific to an epitope on a TCR-V.beta.. The invention also provides a method of assay of the fluids of a person infected with HIV to determine the immunodeficiency of the person which utilizes a binding agent specific to complexes containing anti-TCR-V.beta. antibody bound to TCR-V.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: April 6, 1999
    Assignee: Consorzio per le Biotecnologie
    Inventor: Daniele Primi
  • Patent number: 5891500
    Abstract: Package comprising a polymer blend of ionomer and polybutylene in which at least one seam is made up of the blend being sealed to itself.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: April 6, 1999
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Vincent Brodie, III
  • Patent number: 5891994
    Abstract: A composition is provided which contains a non-naturally occurring peptide or polypeptide comprising at least two or more, and preferably all four amino acid sequences -Asp-Pro-Arg-Leu-Glu-Pro- SEQ ID NO: 6; -Asp-Pro-Lys-Leu-Glu-Pro- SEQ ID NO: 7; -Asp-Pro-Ser-Leu-Glu-Pro- SEQ ID NO: 8; and -Asp-Pro-Asn-Leu-Glu-Pro- SEQ ID NO: 9. This composition, including a number of additional optional peptides or polypeptides, and in a variety of forms, demonstrates a biological activity of inducing antibodies that react with most HIV-1 Tat proteins and impairing the multiplication of HIV-1. Also provided are synthetic genes encoding these peptides, recombinant viruses and commensal bacterium carrying these genes, transfected host cells, and polyclonal or other types of antibodies produced by immunizing other mammals with these aforementioned compositions. Methods for making and using such compositions to lower the viral level of HIV-1 are described.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: April 6, 1999
    Assignee: Thymon L.L.C.
    Inventor: Gideon Goldstein
  • Patent number: 5891624
    Abstract: This invention relates to a method for culturing a virus including the steps of (A) providing cells from a cell line susceptible to infection by the virus and a specimen; (B) treating the cells with a compound of formula RC(O)Q, wherein Q is R, OR, OX or X, each R is independently hydrogen or a hydrocarbyl group containing 1 to about 10 carbon atoms and wherein X is hydrogen or a cation; (C) inoculating the treated cells with the specimen; and (D) incubating the inoculated cells to allow viral growth to proceed.
    Type: Grant
    Filed: June 3, 1997
    Date of Patent: April 6, 1999
    Assignee: University Hospitals of Cleveland
    Inventor: Yung T. Huang
  • Patent number: 5891705
    Abstract: The present invention concerns a method for inactivating a virus for use in e.g. a vaccine, by treating the virus with an ethyleneimine at a pH of less than 7.0, and methods of treatment with the inactivated virus.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: April 6, 1999
    Assignee: Pentose Pharmaceuticals, Inc.
    Inventors: Edward I. Budowsky, Samuel K. Ackerman
  • Patent number: 5891427
    Abstract: Vitaminized air fresheners and room deodorizers are disclosed which permit occupants to directly receive and enjoy the benefits of vitamins with little or no effort intra-nasally. A method for the continuous release of a vitamin containing composition for the delivery of discrete droplets intra nasally absorbed vitamins such as, but not limited to A, C, and D is also disclosed.
    Type: Grant
    Filed: February 28, 1998
    Date of Patent: April 6, 1999
    Inventor: Leo Mettler
  • Patent number: 5888413
    Abstract: In a plasma processing method, a substrate is processed by placing the substrate on an electrode in a vacuum chamber, introducing a gas into the vacuum chamber while discharging gas from inside vacuum chamber, applying a high frequency voltage to a spiral discharge coil while keeping the vacuum chamber internally at a pressure to generate a plasma inside the vacuum chamber. At least one of the control parameters of gas type, gas flow rate, pressure, magnitudes of high frequency powers applied to the coil and the electrode, and their high frequency power frequencies is varied while the substrate is processed. The method includes a step of allowing a plasma density in-plane distribution to be controlled in accordance with the timing of varying any of the control parameters.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: March 30, 1999
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Tomohiro Okumura, Ichiro Nakayama, Yoshihiro Yanagi
  • Patent number: 5888337
    Abstract: An endpoint detector for plasma etching comprises a photo detecting section for receiving an emission spectrum of plasma due to etching gas from a process chamber for providing plasma etching to a processing object so as to detect a specific waveform of the received emission spectrum, a calculating section for detecting an endpoint of an etching process based on a detecting signal sent from the photo detecting means, the photo detecting section comprises a first optical system for detecting light having a specific wavelength from the emission spectrum received from the process chamber so as to be photoelectrically transferred, and a second optical system for detecting a part of the emission spectrum so as to be photoelectrically transferred before light having a specific wavelength is extracted from the emission spectrum by the first optical system, and the calculating section reduces drift of an electrical signal, which is based on light having a specific wavelength extracted from the first optical system, b
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: March 30, 1999
    Assignee: Tokyo Electron Limited
    Inventor: Susumu Saito