Patents Examined by Manahil Mirghani Ali Abdalhameed
  • Methods of use of cyclopamine analogs
    Patent number: 11602527
    Abstract: The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: March 14, 2023
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Michael J. Grogan, Karen J. McGovern, Martin R. Tremblay
  • Pyrimidine derivative kinase inhibitors
    Patent number: 11602534
    Abstract: The present invention relates to a kinase inhibitor, comprising a compound of Formula I or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite or prodrug thereof. The present invention also relates to a pharmaceutical composition comprising the kinase inhibitor, and to uses and methods for using these compounds and compositions to inhibit the activity of wild-type FLT3, mutant FLT3-ITD, PDGFR? and/or PDGFR? kinase in a cell or a subject, as well as uses and methods of these compounds and compositions to preventing or treating kinase-associated conditions in a subject.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: March 14, 2023
    Assignee: Hefei Institutes of Physical Science, Chinese Academy of Sciences
    Inventors: Qingsong Liu, Jing Liu, Xiaofei Liang, Beilei Wang, Kailin Yu, Zongru Jiang, Cheng Chen, Chen Hu, Wenchao Wang, Fengming Zou, Qingwang Liu, Feng Li, Wenliang Wang, Li Wang