Abstract: A patient interface device includes a frame member and a cushion having a main body, a sealing portion, and first and second posts extending from the main body. The frame member defines a first orifice and a second orifice. The first post of the cushion is rotatably received within the first orifice and the second post is rotatably received within the second orifice in a manner that permits the cushion to rotate relative to the frame member.

Abstract: An electrically heated aerosol-generating device includes a main housing having a cavity, a closure body engageable with the main housing to enclose a cartridge in the cavity, and a heater assembly. The heater assembly includes an elongate piercing assembly configured to extend into the open-ended passage of the cartridge and one or more electric heaters. The piercing assembly has a first hollow shaft portion connected to the main housing and a second hollow shaft portion connected to the closure body. The first and second hollow shaft portions have first and second piercing surfaces configured to breakthrough first and second frangible seals when the cartridge is enclosed in the cavity.

Abstract: Systems and methods for producing nitric oxide (NO) to be used in medical applications are provided. In some embodiments, systems and methods are provided for a NO generator that is capable of generating a desired concentration of NO to be provided to a respiratory system for inhalation by a patient.

Abstract: This disclosure describes systems and methods for providing novel adaptive base flow scheduling during ventilation of a patient to optimize the accuracy of estimated exhaled tidal volume. Further, this disclosure describes systems and methods for providing novel adaptive inspiratory trigger threshold scheduling during the novel adaptive base flow scheduling.

Abstract: A system for delivering oxygen comprises an oxygen source; a ventilator operatively connected to the oxygen source to receive a supply of oxygen therefrom; a valve having a) an open position in which the ventilator receives the supply of oxygen from the oxygen source and b) a closed position in which the ventilator is not in fluid communication with the oxygen source; a sensor configured to measure breath flow information for the patient; and a computer system to: determine a volume of gas delivered to the patient during a breath cycle of the patient and an inspiratory volume of gas delivered to the patient during an inspiration phase of the breath cycle by using the breath flow information; and provide input to the valve based on the determined volumes, the provided input causing a movement of the valve between the open and the closed positions.

Abstract: A fluid control device includes a case including an internal space that is partitioned by a partition wall into an air blowing chamber and a control chamber. A dividing wall is disposed inside the air blowing chamber to partition an internal space of the air blowing chamber into a first air blowing chamber and a second air blowing chamber. A fan unit is housed in the second air blowing chamber. A differential pressure sensor senses a differential pressure between a pressure inside the first air blowing chamber and a pressure inside the second air blowing chamber. A controller controls a fan based on the sensed differential pressure.

Abstract: A patient interface assembly includes a flexible cushion configured to sealingly engage the patient's nares and a frame with a pair of flexible extending members that extend laterally from opposite sides of the frame. The frame and the flexible cushion together form a chamber. The patient interface assembly also includes a positioning and stabilising structure configured to maintain the flexible cushion in engagement with the patient's nares. The positioning and stabilizing structure has a pair of headgear straps. Each headgear strap is connected to a respective one of the flexible extending members. The flexible extending members do not form an airflow path for the breathable gas. The headgear straps have a multi-layered structure, at least one layer being made of fabric and at least one layer being made of plastic. In addition, the at least one plastic layer is a rigidizer that adds rigidity to the respective headgear strap.

Abstract: A nasal assembly for delivering breathable gas to a patient includes a frame having lateral connector, a cushion with a pair of nozzles, and a clip to secure the cushion to the frame. The frame includes a vent channel and a plurality of vent holes. The frame/cushion includes structure (lugs/cut outs) to prevent the assembly of an unvented frame with an unvented cushion, for safety purposes. The frame includes cored portions that interface with corner lugs provided on the cushion. A patient interface includes a frame, a cushion (nasal mask, nasal-oro mask, nozzles, etc.) and a vent assembly including a pattern of vent holes including at least two rows.

Abstract: A method of controlling a medical device is disclosed for delivering respiratory therapy to a user to treat sleep-disordered breathing, for instance obstructive sleep apnea, Cheyne-Stokes respiration etc. by estimating the user's CO2 percentage or concentration from a dynamic lung model driven by an observed respiration signal. The estimated user's CO2 percentage or concentration can be used to predict breathing events, such as hypopnea and apnea. The predictive capacity can be used for adjusting the respiratory therapy as required or for applying a ramp cycle therapy, in an attempt to reduce the prevalence and adverse effects of the breathing events. In other examples a variable ventilation therapy is provided in which pressure is supplied between first and second pressures, with the pressure being increased over more than one breath, and then dropped relatively rapidly, for example during expiration of a single breath.

Abstract: Systems and methods for novel ventilation that allows the patient to trigger or initiate the delivery of a breath are provided. Further, systems and methods for triggering ventilation based on signal distortion of a monitored patient parameter are provided.

Abstract: Provided is a mask fitting level determination device that has a significantly simple component configuration, that can be driven by a battery, that can be reduced in size to a palm size, that is inexpensive, that is operated by a simple operation method, and that does not require proficiency for accurate measurement. The mask fitting level determination device includes: a mask inner pressure detection unit 2 that is inserted between a face surface F of a mask wearing person and a worn mask 1; and a circuit control unit that sets a predefined threshold value in accordance with strength of breathing of the mask wearing person and determines a fitting level on the basis of a reference pressure value and a mask inner pressure value measure by the mask inner pressure detection unit 2; and a display unit 3 that displays the fitting level determined by the circuit control unit to the mask wearing person.

Abstract: A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, and a duration of safe apnoea is determined from the obtained information. A respiratory therapy system has one or more patient interfaces. A processor is configured to determine a duration of safe apnoea based on obtained information relating to a respiratory indicator.

Abstract: A connection assembly for a respiratory therapy system, comprising: an outlet assembly, said outlet assembly including an outlet housing and a swivelling disc located on said outlet housing, said outlet housing and said swivelling disc defining, at least in part, a recess; an outlet connector located at an end of a tube portion, said outlet connector including an electrical connector; and a cable having a first end to connect to the electrical connector and a second end to connect to at least one electrical component of the respiratory therapy system, said cable having a slack portion, wherein said outlet connector and said swivelling disc are rotatable in unison between a first position and a second position, and wherein the slack portion of the cable extends from the recess and wraps around the swivelling disc as the swivelling disc is rotated from the first position to the second position.

Abstract: A respiratory apparatus may employ ultrasonic welds. The ultrasonic welding may be used to join a variety of headgear, mask and accessory components. This process may enhance comfort, fit and/or performance of the joined components and/or overall mask assembly. A component may be a single layer component such as a textile or fabric, or a composite or multiple layer component such as fabric and foam composites, or outer fabric layers and inner spacer fabrics. Further, a component may be a strap, some other headgear component, a mask component, an accessory component or the like.

Abstract: Provided are a bioactivation method for enhancing a neural activity and/or a blood circulation activity of a living body and a hydrogen generating device for executing this method. In the method, a gas mixture containing hydrogen and oxygen at predetermined concentrations is suctioned by spontaneous breathing continuously for a predetermined time. Moreover, this hydrogen generating device for executing the bioactivation method for enhancing a neural activity and/or a blood circulation activity of a living body includes a body cover member including a battery, a control substrate for controlling power supply from the battery, and a pair of positive/negative electrodes electrically conducted with or shut down from a positive electrode and a negative electrode of the battery by the control substrate.

Abstract: The device of the invention is equipped with a pressure sensor and a control unit, and the control unit judges a point at which a pressure gradient calculated from a signal of the pressure sensor becomes larger in the absolute value than a pressure gradient threshold as an inspiration sensing point and starts respiratory gas supply. In addition, the device judges from a frequency of the inspiration sensing point during predetermined time whether a pressure gradient threshold used as a criterion for the inspiration sensing point corresponds to an activity state of the user, and when the pressure gradient threshold does not correspond to the activity state, switches the pressure gradient threshold to another threshold and thus fits the pressure gradient threshold to the activity state.

Abstract: The present invention relates to a plurality of ventilation devices, to ventilation devices having visualization apparatuses, and to methods for operating the ventilation devices. The intent is to minimize the energy input into the at least one airway of a patient as a result of the ventilation.

Abstract: A patient interface device and cushion for the device are respectively disclosed, for preferred CPAP and BiPAP breathing masks. The cushion has a composite structure with an open rounded polygonal profile defining a mask side layer and a slip-resistant fibrous patient side layer, with an intermediate barrier layer positioned between the first and second layers. The layers are integrally bonded together into a three-dimensional conformation defining a J-shaped cross section and an inboard patient side curl opening into an air chamber juxtaposed with one or more of the patient's airways. The body exhibits flexibility between about 4 and about 10 Taber Stiffness Units. Method and apparatus for making the cushion are further described.

Abstract: Systems and methods are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a vaporizing chamber configured to hold a liquid anesthetic agent, and an inductive heating element positioned exterior to the vaporizing chamber and housed within a gas-tight barrier, the inductive heating element operated to selectively heat a target.

Abstract: Disclosed is a device for respiration with at least one pressurized gas source for respiratory gas and a sensor unit for determination of respiratory gas pressure and/or flow rate and/or volume and a control unit. The control unit records an individual breathing pattern of a patient and from this forms an individual pressure profile for the patient which is provided by the pressurized gas source.