Abstract: An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.

Abstract: An ultrasound diagnostic apparatus includes an ultrasound probe, a reference image holding unit that holds an ultrasound image acquired by fixing a position of the ultrasound probe as a reference image, a movement vector calculation unit that calculates a movement vector between two ultrasound images, a movement vector integration unit that integrates the movement vector from a time when the reference image is held to a current time, a deformed image generation unit that generates a deformed image in which the current ultrasound image is moved and changed to a time when the reference image is held based on an integration result, a tomographic plane determination unit that compares the deformed image with the reference image to determine whether tomographic planes of the current ultrasound image and the reference image are the same as each other, and a determination result notification unit that notifies a user of a determination result.

Abstract: Embodiments for assessing flow at an anatomical region of interest are disclosed. One embodiment uses pulsed contrast media injections at a known frequency along with corresponding image data to derive a measurement of blood flow velocity at the region of interest. Another embodiment uses incremental changes in known contrast media injection flow rates to match the blood flow rate relative to one of these known contrast media injection flow rates based on the presence of a particular indicia in image data. For example, this indicia can be the flow of contrast media out from a coronary artery back into the aorta or the onset of a steady state pixel density. A further embodiment uses contrast media injections that are synchronized with the cardiac cycle. For example, contrast media injections can be synchronized with the diastolic and/or systolic phases and used to measure blood flow accordingly.

Abstract: According to one embodiment, an image processing apparatus includes at least one of memory and processing circuitry. The memory stores a first medical image of a heart area acquired in a plurality of directions and a second medical image of the heart area acquired in real time. The processing circuitry is configured to set, based on the first medical image, each of a valve boundary line indicating a boundary between leaflets of a heart valve and an insertion point on an inner wall through which a catheter is inserted, generate a navigation graphic including the valve boundary line and the safety lines by generating a plurality of safety lines individually connecting the insertion point to ends of the valve boundary line, and superimpose the navigation graphic on the second medical image to generate a superimposed image.

Abstract: A medical image diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to derive a subject-specific regression model that indicates a relationship among a cardiac cycle, systole, and diastole of the subject. The processing circuitry is configured to derive timing of a data acquisition in a synchronization imaging performed in synchronization with heartbeats of the heart of the subject, by using the derived regression model and electrocardiographic information of the subject obtained during an image taking process. The processing circuitry is configured to control the synchronization imaging so that the data acquisition is performed with the derived timing.

Abstract: According to one aspect of the invention, a system for medical object tracking is provided. The system includes a plurality of radio frequency transceivers where each of the plurality of radio frequency transceivers are configured to emit a radio frequency signal at a respective frequency. The system includes a radio frequency beacon removably attachable to a medical object where the radio frequency beacon configured to: reflect the radio frequency signals from the plurality of radio frequency transceivers, and emit vibration-based signals. The system includes a control device in communication with the plurality of radio frequency transceivers where the control device includes processing circuitry configured to determine a location of the medical object in three-dimensional space based at least in part on the reflected radio frequency signals and vibration-based signals.

Abstract: An optical measurement system comprising an optical source configured for delivering sample light in an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, an optical detector configured for detecting the physiological-encoded signal light, and a processor configured for acquiring a TOF profile derived from the physiological-encoded signal light, the initial TOF profile having an initial contrast-to-noise ratio (CNR) between a plurality of states of a physiological activity in the anatomical structure. The processor is further configured for applying one or more weighting functions to the initial TOF profile to generate a weighted TOF profile having a subsequent CNR greater than the initial CNR between the plurality of states of the physiological activity.

Abstract: A method of transcranial brain optical imaging including obtaining a Laser Speckle (LS) image of cranial blood vessels of a subject, obtaining a Dynamic Fluorescence (DF) image of the cranial blood vessels of the subject, and combining the LS image and the DF image producing a combined color image which displays both structure of the cranial blood vessels and perfusion of blood along the cranial blood vessels. Related apparatus and methods are also described.

Abstract: A respiratory monitoring device comprises: a light source (30) arranged to generate a projected shadow (S) of an imaging subject (P) positioned for imaging by an imaging device (8); a video camera (40) arranged to acquire video of the projected shadow; and an electronic processor (42) programmed to extract a position of an edge of the projected shadow as a function of time from the acquired video. In some embodiments, the light source is arranged to project the shadow onto a bore wall (20) of the imaging device, and the video camera is arranged to acquire video of the projected shadow on the bore wall. The electronic processor may be programmed to extract the position of the edge (E) as a one-dimensional function of time (46) based on the position of the edge in each frame of the acquired video and time stamps of the video frames.

Abstract: A first acoustic wave image and a second acoustic wave image are displayed on top of each other in different display colors, and a first operation icon for selecting the first acoustic wave image and a second operation icon for selecting the second acoustic wave image are displayed on operation icon display unit. The first operation icon and the second operation icon are displayed on top of each other in a display order identical to a display order of the first acoustic wave image and the second acoustic wave image that are displayed on top of each other on image display unit.

Abstract: Among the various aspects of the present disclosure is the provision of systems and methods of velocity-matched ultrasonic tagging in photoacoustic flowgraphy.

Abstract: Provided herein are systems and methods comprising localization agents. For example, provided herein are systems and methods for the placement of localization devices within biological systems and the detection of such localization devices for targeted surgeries or other medical procedures. For example, provided herein are systems comprising one or more miniature detectable devices that are placed into a target location and activated by remote introduction of a magnetic field.

Abstract: Tissue localization devices and methods of localizing tissue using tissue localization devices are disclosed. The tissue localization device can comprise a handle comprising a delivery control, a delivery needle extending out from the handle, and a localization element within the delivery needle. The localization element can be deployed out of the delivery needle or retracted back into the delivery needle when the delivery control is translated in a first direction or a second direction, respectively. The localization element can be coupled to a flexible tracking wire.

Abstract: A guidewire insertion tool configured to measure a length of an anatomic region. The tool can include a housing, a light chamber, and a track at least partially extending through the light chamber. The track is adapted to guide a guidewire as it is advanced through the insertion tool. The tool can also include an optical sensor assembly in optical communication with the light chamber. The optical sensor assembly can include one or more light sources, an optical sensor, and a magnifier. The one or more light sources can be adapted to direct light toward a portion of the guidewire within the track, and the optical sensor can be adapted to receive reflected light from the portion of the guidewire within the tract. A processing unit can analyze data from the optical sensor assembly to determine the length of the anatomic region and output the measurement to a display.

Abstract: An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.

Abstract: A method includes registering a fluoroscopic imaging system and a position tracking system to a common frame of reference. A region of interest is marked in a patient body by the position tracking system. Using the common frame of reference, a field of view of the fluoroscopic imaging system is set such that the region of interest appears in the field of view.

Abstract: Various approaches to generating and maintaining an ultrasound focus at a target region include configuring a controller to cause transmission of treatment ultrasound pulses from a transducer having multiple transducer elements; cause the transducer to transmit focusing ultrasound pulses to the target region and generate an acoustic reflector therein; measure reflections of the focusing ultrasound pulses from the acoustic reflector; based at least in part on the measured reflections, adjust a parameter value associated with one or more transducer elements so as to maintain and/or improve the ultrasound focus at the target region.

Abstract: A surface property measurement technology by which a surface property of a substance can be evaluated with high accuracy, is provided. A surface property measurement method includes radiating an ultrasonic wave to a measurement target and acquiring a reflected signal from the measurement target; calculating, by a measurement apparatus, a maximum value of a cross-correlation function between the reflected signal from the measurement target and a reference reflected signal from a reference substance acquired in advance; calculating a reflection component at an interface, by using the maximum value of the cross-correlation function; and outputting, as a measurement value, one of an acoustic impedance of the measurement target or an acoustic impedance of the reference substance, according to a result of comparing the reflection component with the reference reflected signal.

Abstract: A system for delivering ultrasound energy to an internal anatomical target includes an ultrasound transducer having multiple transducer elements collectively operable as a phased array; multiple driver circuits, each being connected to at least one of the transducer elements; multiple phase circuits; a switch matrix selectably coupling the driver circuits to the phase circuits; and a controller configured for (i) receiving as input a target average intensity level and/or an energy level energy to be applied to the target and/or a temperature level in target, (ii) identifying multiple sets of the transducer elements, each of the sets corresponding to multiple transducer elements for shaping and/or focusing, as a phased array, ultrasound energy at the target across tissue intervening between the target and the ultrasound transducer, and (iii) sequentially operating the transducer-element sets to apply and maintain the target average energy level at the target.

Abstract: A medical image processing apparatus comprises processing circuitry configured to: obtain a medical imaging data set representative of at least part of at least one surface; render from the medical imaging data set at least one image of the at least part of the at least one surface, wherein the or each image is rendered using a respective lighting configuration; and determine a measure of lighting quality for the or each rendered image; wherein, for the or each rendered image, the determining of the measure of lighting quality comprises, for each of a plurality of locations on the at least part of the at least one surface, determine a correspondence between a curvature of the at least one surface at that location and a lighting value at that location, wherein the lighting value is obtained from the rendering of the image; and determine the measure of lighting quality based on the determined correspondences.