Abstract: The present embodiment relates to a method and apparatus for measuring a tissue variation signal (e.g. a photoplethysmographic (PPG) signal) without large direct current (DC) or low frequency (LF) offset which normally limit the sensor accuracy through motion artefacts and/or dynamic range requirements. The proposed solution is based on a separation of the PPG signal from the disturbance. This can be achieved by creation of a modulated PPG signal, or by creation of a differential PPG signal and an optimized sensor configuration which is adapted to remove DC or LF components.

Abstract: The ultrasonic probe includes a transducer array that generates ultrasonic waves, a backing layer that is provided on a rear surface of the transducer array, a pulsating heat pipe that absorbs heat generated in the transducer array, and a heat radiation unit that receives the heat from the pulsating heat pipe to emit the received heat to the outside.

Abstract: A drive assembly for driving an imaging catheter has a rotatable fiber and a rotatable drive shaft. The drive assembly includes a fiber optic rotating junction and a motor configured to rotate the rotatable portion of the fiber optic rotating junction. In some embodiments, the drive assembly includes a sensor configured to detect a rotational position of the fiber optic rotating junction and a processor configured to obtain the detected rotational position and stop the motor only when the fiber optic rotating junction is in a predetermined rotational position. In some embodiments, the motor includes a hollow shaft through which at least a portion of the fiber optic rotating junction extends.

Abstract: The invention proposes to detect and track an intervention device in a 2D fluoroscopy image and to steer an ultrasound probe beam towards this device. Therefore, a method and corresponding system is proposed, by which an ultrasound probe is registered in a fluoroscopy image, wherein the registering includes the estimation of the position and of the orientation of the probe relative to the fluoroscopy.

Abstract: An interventional system with real-time ablation thermal dose monitoring includes an interventional tool, an ultrasound transmitter at least one of attached to or integral with the interventional tool, an ultrasound receiver configured to receive ultrasound signals from the ultrasound transmitter after at least one of transmission through or reflection from a region of tissue while under an ablation procedure and to provide detection signals, and a signal processing system configured to communicate with the ultrasound receiver to receive the detection signals and to calculate, based on the detections signals, a thermal dose delivered to the region of tissue in real time during the ablation procedure.

Abstract: The present disclosure provides a method for characterizing a region of interest within or between biological tissue. The method comprises inserting at least a portion of a probe into the region of interest and directing electromagnetic radiation to the region of interest and receiving electromagnetic radiation from the region of interest using the probe in a direction that is transversal to a length of the probe. Further, the method comprises directing a fluid to the region of interest through a portion of the probe and analyzing received electromagnetic radiation.

Abstract: Systems and methods for classifying tissue using quantitative ultrasound techniques. Parameters are calculated directly from raw echo signal data acquired from a region-of-interest during an ultrasound scan and parametric maps are produced using these parameters. These parameters can be calculated after normalizing the echo signal data using reference data so as to mitigate the effects of variations in instruments settings, ultrasound beam diffraction, and attenuation effects. First-order and second-order statistical measures are computed from these parametric maps, and are used to classify the tissue or tissues in the region-of-interest. Using these systems and methods, tissue can be classified with different levels of classification. For example, a tissue characterized as malignant cancer can additionally be graded (e.g., Grade I, II, or III).

Abstract: Disclosed is a method for operating an ultrasonic diagnostic apparatus. The method includes transmitting separate first and second ultrasonic signals to an object, receiving a first echo signal which corresponds to the first ultrasonic signal and a second echo signal which corresponds to the second ultrasonic signal, separating the received first and second echo signals in order to generate first ultrasonic data which corresponds to the first echo signal and second ultrasonic data which corresponds to the second echo signal, and displaying a first ultrasonic image which is generated based on the first ultrasonic data and a second ultrasonic image which is generated based on the second ultrasonic data. The first ultrasonic image is an ultrasonic image of a first cross-sectional surface of the object, and the second ultrasonic image is an ultrasonic image of a second cross-sectional surface of the object.

Abstract: The present invention relates to a detachably joined ultrasonic probe device, including modular ultrasonic probe and a case for detachably joining with the modular ultrasonic probes, which enables the user to select a suitable ultrasonic probe according to desired performance and diagnosis frequency region. The device according to the present invention includes: a plurality of ultrasonic probe modules horizontally arranged in the direction of generating an ultrasonic wave; a case consisting of an outer housing with one open side for receiving and enclosing the plurality of ultrasonic probe modules, and a separation housing provided between the plurality of ultrasonic probe modules for separating the ultrasonic modules from one another, so as to detachably join with the ultrasonic modules; and a control module installed in the case for controlling the plurality of ultrasonic probe modules.

Abstract: Various examples are provided for photoacoustic image reconstruction and processing utilizing a backprojection approach. In one example, among others, a method for producing an image with a photoacoustic imaging system includes scanning an object with a plurality of light beams, detecting a plurality of acoustic signals produced by the light beams, and generating a reconstructed image from the plurality of acoustic signals by filtered backprojection (FBP) that utilizes a weighted ramp filter. In another example, a system includes a plurality of acoustic detector units and a processing unit. The acoustic detector units can receive an acoustic wave and convert it to time dependent electrical signals. The processing unit can reconstruct an image of the subject from the time-dependent electrical signals by FBP that utilizes a weighted ramp filter. In another example, non-transitory computer readable medium stores a program that can cause a processing unit to reconstruct an image.

Abstract: The elongated substantially tubular introducer extends along a longitudinal axis from a proximal end to a sharpened distal end. The introducer includes at least one side window positioned at a predefined location along the longitudinal axis from a distal tip. The elongated stylet is adapted to be received in a lumen of the tubular introducer to provide structural support for the introducer during insertion and removal. The introducer can be inserted as part of a procedure that includes generating a first image to identify target tissue for biopsy, inserting the introducer into the location of the target tissue based on the first image and then taking a second image, in a substantially transverse or orthogonal direction from the first image in order to ensure proper alignment of target tissue in relation to the at least one side window or to allow for repositioning of the introducer.

Abstract: The Energy Field and Target Correlation System automatically correlates the characteristics of target particles and a living organism to compute the characteristics of an energy field that is applied to a living organism to activate the target particles which are bound to or consumed or taken up by invasive agents in the living organism to produce detectable effects which can be used to treat the invasive agents. The energy field must be crafted to properly control the response and localize the extent of the illumination. The System automatically selects a set of energy field characteristics, including: field type, frequency, field strength, duration, field modulation, repetition frequency, beam size, and focal point. The determined energy field characteristics then are used to activate field generators to generate the desired energy field.

Abstract: A method of fabricating miniature ultrasound transducers includes receiving a wafer on which a plurality of miniature ultrasound transducers is formed. The miniature ultrasound transducers each includes: a transducer membrane that contains a piezoelectric material and a first bond pad and a second bond pad each electrically coupled to the transducer membrane. A protective layer is conformally deposited over the plurality of miniature ultrasound transducers from a front side of the wafer. A first etching process is performed to form a plurality of first trenches that extend into the wafer from the front side. The first trenches are etched through the protective layer. The first trenches are disposed between adjacent miniature ultrasound transducers. A second etching process is performed to remove portions of the protective layer disposed over the first and second bond pads, thereby exposing the first and second bond pads.

Abstract: The present disclosure relates generally to equipment and procedures in the field of surgery and/or diagnostics and, more particularly, to instruments, assemblies and methods for undertaking surgical and/or diagnostic procedures that involve and/or are in proximity to the brain (e.g., cranial procedures and/or surgery). The disclosed assemblies generally include a handle member and an elongated probe that includes an ultrasound transducer. The assemblies may be used in conjunction with K-wires/guidewires, tubular members (e.g., EVD catheters and/or ventricular drains), endoscopes/cameras, and accessory items such as curettes, probes, knives, suction devices, scissors, cautery units, forceps, grasping devices and the like. Advantageous medical diagnostic and surgical instruments, assemblies and methods are provided for use during a broad variety of clinical applications and procedures (e.g.

Abstract: An ultrasound diagnostic apparatus and a method of producing an ultrasound image capable of accurately determining the boundary of an intima-media complex in an ultrasound image and measuring an intima-media thickness with high precision are provided. A candidate vascular wall boundary point determiner determines one or more candidate vascular wall boundary points based on a sound ray signal extending in a scanning direction in an ultrasound image. A boundary determiner determines a vascular wall boundary point from among the candidate vascular wall boundary points based on a third evaluation value and determines a vascular wall boundary, the third evaluation value being calculated based on a first evaluation value representing accuracy of each of the determined candidate vascular wall boundary points as a vascular wall boundary point and a second evaluation value representing similarity between the sound ray signal and the adjacent sound ray signal.

Abstract: A portable ultrasound system having an enhanced user interface is disclosed herein. In one embodiment, a portable ultrasound system can include a hand-held base unit configured to present a graphical user interface that contains a first control area, a second control area, and an active image area. The first control area can have a number of graphical tools that can each be selectively activated by a user's finger. The second control area can include a control area having plurality of controls that can be selectively activated by the user's thumb to select a tool property of a number of tool properties associated with the selected one of the graphical tools. The active image area can display an ultrasound image, and the selected one of the graphical tools can be overlaid onto the image with the user-selected tool property.

Abstract: A miniature, low-power, optical sensing device that operates in the harsh electromagnetic environment of a magnetic resonance imaging system is provided. The device includes a means of transferring imaging data obtained with the optical sensor out of this harsh electromagnetic environment without requiring a galvanic connection. It is practical to power the device using a small battery that is compatible with the harsh environment. In other embodiments, the device is powered using ‘power over fiber’ or by taking power by ‘power harvesting’ directly from the harsh electromagnetic environment. One embodiment is to directly integrate the device into a magnetic resonance imaging (MRI) head coil, using a wired connection to the head coil to provide electrical power. Here the wired connection does not penetrate the Faraday cage of the MRI system or cross into the bore of the MRI system from outside the bore.

Abstract: The present invention relates to stenosis therapy planning. A first volumetric data set is received by medical imaging of at least part of an artery comprising a stenosis. At least one two-dimensional image data (of the stenosis is received. A first arterial pressure drop is determined around the stenosis. A second volumetric data set is generated by registering the at least one two-dimensional image data with the first volumetric data set. A third volumetric data set is generated by simulating a geometry modification of the stenosis in the second volumetric data set and a second arterial pressure drop is estimated around the stenosis in the third volumetric data set.

Abstract: Devices and systems are provided for tracking a position and orientation of a handheld implement, such that the handheld implement may be trackable with an overhead tracking system. A support member secures one or more markers relative to a longitudinal portion of the handheld implement, and a marker plane containing the markers is orientated an angle relative to a longitudinal axis of the longitudinal portion. A marker assembly may include a support member for supporting the markers, and a connector for removably attaching the marker assembly to one or more handheld implements. The marker assembly may be configured to be removably attachable to a plurality of connection adapters, where each connection adapter is further connectable to a handheld implement, optionally at a calibrated position, such that a single connection adapter can be optionally employed to track a plurality of handheld implements. The handheld implement may be a medical instrument.

Abstract: In illustrative implementations of this invention, a photoplethysmographic device measures variations of light that is reflected from, or transmitted through, human skin. In some implementations, the device includes a camera that takes the measurements remotely. In others, the device touches the skin during the measurements. The device includes a camera or other light sensor, which includes at least orange, green and cyan color channels. In some cases, such as a contact device, the device includes three or more colors of active light sources, including at least orange, green and cyan light sources. A computer analyzes the sensor data, in order to estimate a cardiac blood volume pulse wave. For each cardiac pulse, a computer detects the systolic peak and diastolic inflection of the wave, by calculating a second derivative of the wave. From the estimated wave, a computer estimates heart rate, heart rate variability and respiration rate.