Patents Examined by Mark V Stevens
  • Glyceryl polyrhamnosides, process for the preparation thereof, and cosmetic and/or pharmaceutical composition comprising same
    Patent number: 11337911
    Abstract: Composition based on a polyol of formula HO—CH2-CHOH—CH2-OH and on alkyl polyrhamnosides of formula HO—CH2-CHOH—CH2-O-(Rham)x-H; process for preparing same, and cosmetic or pharmaceutical composition comprising same.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: May 24, 2022
    Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC
    Inventors: Georges Manuel Dacosta, Jérome Guilbot, Stéphane Dessilla, Laetitia Cattuzzato
  • Phenylquinoline compositions for treatment of ocular disorders and conditions
    Patent number: 11337968
    Abstract: Compositions containing a phenylquinoline derivative compound having peroxisome proliferator-activated receptor a (PPAR?) agonistic activity, and methods of their use in enhancing PPAR? activity in retinal cells, and in treating ocular disorders or conditions, such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: May 24, 2022
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Jian-xing Ma, Elizabeth Moran, Guotao Deng, Adam S. Duerfeldt
  • Supramolecular alginate materials for biomedical applications
    Patent number: 11331415
    Abstract: The present invention relates to the unexpected discovery of novel hydrogel formulations that allow for the encapsulation and delivery of living cells and/or drugs to a subject in need thereof. In certain embodiments, the hydrogel compositions of the invention comprise bound bioactive molecules that promote long-term cell viability and allows for the development of vasculature. The invention further provides methods of delivering viable cells and/or drugs to a subject comprising administering the compositions of the invention to the subject in need thereof.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: May 17, 2022
    Assignee: UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE
    Inventors: Rachael A. Oldinski, Jennifer N. Etter
  • Abuse-deterrent dosage forms containing esketamine
    Patent number: 11324707
    Abstract: Disclosed herein are immediate release oral dosage forms that contain abuse-deterrent and abuse-resistant features. In particular, the disclosed dosage forms can provide deterrence of abuse by ingestion of multiple individual doses. The disclosed dosage forms can likewise provide protection from overdose in the event of accidental or intentional ingestion of multiple individual doses. The dosage forms may also exhibit abuse resistant properties when physically manipulated, and also when physically manipulated and then administered in a manner not consistent with oral dosing. The dosage forms may also exhibit abuse resistant properties when administered in a manner intended to result in administration of the esketamine in a higher than therapeutic dose.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: May 10, 2022
    Assignee: CLEXIO BIOSCIENCES LTD.
    Inventors: Derek Moe, Randal Seburg, Sagar Rane
  • Method to prepare pharmaceutical compositions of suggamadex
    Patent number: 11324692
    Abstract: The present invention relates to a method to prepare pharmaceutical compositions of sugammadex, to pharmaceutical compositions of sugammadex and uniform pharmaceutical batches of said compositions.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: May 10, 2022
    Assignee: Galenicum Health S.L.U.
    Inventors: Luis Gomez Coello, Javier Torrejón Nieto
  • Compositions and methods for inhibiting biofilm-forming bacteria
    Patent number: 11318149
    Abstract: The present disclosure provides, among other things, compositions and methods useful for inhibiting biofilm-forming bacteria. For example, the compositions and methods described herein can be used to inhibit the proliferation, viability, and/or biofilm-forming activity, of biofilm-forming bacteria.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: May 3, 2022
    Assignee: Board of Trustees of Michigan State University
    Inventors: Christopher Waters, Michael Maiden
  • Opioid receptor modulator dosage formulations
    Patent number: 11311516
    Abstract: Abuse deterrent solid dosage formulations containing 5-({[2-Amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid, and processes for the preparation and administration of these formulations.
    Type: Grant
    Filed: September 22, 2021
    Date of Patent: April 26, 2022
    Assignee: Allergan Holdings Unlimited Company
    Inventors: Tim Costello, Jens Jozef Ceulemans, Eugeen Maria Jozef Jans, Philip Erna H. Heyns
  • Pharmaceutical preparations and methods to manage weight and to modulate the gut microbiota
    Patent number: 11311573
    Abstract: A pharmaceutical preparation, comprising: A) A plurality of particles, each particle comprising: 1) a core comprising at least one agent that increases oxygen tension and/or redox potential and/or pH in the colon of a subject following administration to the subject, and 2) an enteric coating encasing the core; and B) a capsule or sachet encasing the plurality of particles. Methods of weight management for a subject, comprising administering the pharmaceutical preparation to a subject in need thereof.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: April 26, 2022
    Assignee: Xeno Biosciences Inc.
    Inventor: Hasan Celiker
  • Prebiotic and probiotic cookie preparation
    Patent number: 11311478
    Abstract: A cookie that provides a prebiotic effect and/or a probiotic effect to a consumer is described. The cookie fails to contain refined sugars, synthetic vitamins, genetically modified organisms (GMOs), artificial sweeteners, and artificial preservatives. The cookie comprises at least two baked food compositions formed into a biscuit. Each of the at least two baked food compositions contains a polyphenol, a resistant starch, and a prebiotic soluble fiber. A crème filing is sandwiched between the at least two baked food compositions. The crème filing comprises a resistant starch, a nut butter, a vegetable fat, and spores of a probiotic bacterium. Consumption of the cookie increases Lactobacillus bulgaricus and butyrate in the consumer.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: April 26, 2022
    Assignee: Uplift Food
    Inventor: Kara Landau
  • Propanediol monoacetate mononitrate
    Patent number: 11306054
    Abstract: The present invention relates to propanediol monoacetate mononitrate as well as the use thereof as antimicrobial agent, in particular for cosmetic applications.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: April 19, 2022
    Assignee: DSM IP ASSETS B.V.
    Inventors: Christine Mendrok-Edinger, Peter Riebel, Angela Wildermann
  • Cosmetic compositions with a micro-mesh structure
    Patent number: 11291286
    Abstract: A topical composition comprising a Polymer, a high molecular weight hyaluronic acid (HWM HA) and/or its salt, a low molecular weight hyaluronic acid (LWM HA) and/or its salt, and a polyamino acid and/or its salt; and water and a method for identifying a test polymer that forms a micro-mesh structure when combined with such ingredients.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: April 5, 2022
    Assignee: ELC MANAGEMENT LLC
    Inventors: Snehal Shah, Hua Wang, Zhequan Xu, Mary Ann Smail, Milan Franz Sojka, Daniela Bratescu
  • Delivery of surfactant soluble anti-dandruff agent
    Patent number: 11291616
    Abstract: A hair care composition directed to from about 14% to about 40% of one or more surfactants; from about 0.1% to 10% of one or more surfactant soluble antidandruff agents; wherein when the hair care composition is diluted to 1.3% surfactant concentration has a ratio of surfactant diffusion coefficient to soluble agent diffusion coefficient less than 0.6 or greater than 1.4.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: April 5, 2022
    Assignee: The Procter and Gamble Company
    Inventors: Debora W Chang, Eric Scott Johnson, Robert Wayne Glenn, Jr., Todd Ryan Thompson, Allison Lynn Edwards, Michelle Lynn Carter
  • Soluble metallogels including antimicrobial silver metallogels
    Patent number: 11291203
    Abstract: A product includes a metallogel material having metal ions dispersed in an assembly having an organic compound. A method includes combining a metal salt, an organic compound precursor, and a glyme for forming a metallogel material having metal ions dispersed in an assembly having an organic compound.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: April 5, 2022
    Assignees: Lawrence Livermore National Security, LLC, Colorado State University Research Foundation
    Inventors: William Compel, Keith Morrison, James Armstrong, Christopher J. Ackerson
  • Solid drug implants for intracochlear delivery of therapeutics for the treatment of Otic disorders
    Patent number: 11291671
    Abstract: The present invention provides for pharmaceutical preparations, devices, systems and methods for the treatment of otic diseases and conditions. In various embodiments, the preparations, devices, systems and methods enable sustained drug release for the treatment or prevention of hearing loss, infections, and other pathological conditions of cochlea and inner ear.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: April 5, 2022
    Assignee: O-Ray Pharma, Inc.
    Inventors: William H. Slattery, Thomas Smith, Erik Pierstorff, Marc M. Baum
  • Iron compositions and methods of making and using the same
    Patent number: 11292813
    Abstract: The present invention involves a novel aqueous iron composition. The aqueous iron composition includes iron sucrose and bicarbonate. The aqueous iron composition of the invention exhibits enhanced renal protective effects relative to conventional iron sucrose compositions.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: April 5, 2022
    Assignee: RENIBUS THERAPEUTICS, INC.
    Inventors: Donald Jeffrey Keyser, Alvaro F. Guillem, Richard A. Zager
  • Bioimplant with evanescent coating film
    Patent number: 11278642
    Abstract: To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: March 22, 2022
    Assignees: TAKAO HOTOKEBUCHI, KYOCERA CORPORATION
    Inventors: Takao Hotokebuchi, Iwao Noda
  • Stable parenteral composition of lacosamide
    Patent number: 11278634
    Abstract: In some embodiments, the disclosure provides a method of making a sterile lacosamide composition, the method comprising; (a) obtaining a composition comprising (i) about 5 mg/mL to about 20 mg/mL lacosamide, (ii) about 5 mg/mL to about 12 mg/mL sodium chloride, and (iii) water, (b) placing the composition of (a) into a glass vial, wherein the glass vial has an ammonium sulfate coating, (c) sealing the composition inside the glass vial; and (d) autoclaving the sealed glass vial of (c) at 121° C. at 15 lbs pressure for 15 minutes, wherein the pH of the composition in (d) is substantially the same as the pH of the composition after (a), and wherein the composition of (d) comprises less than about 0.2% (wt/wt) of Impurity A, Impurity B, Impurity C, Impurity D, Impurity E or Impurity F.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: March 22, 2022
    Assignee: EXTROVIS AG
    Inventors: Krishna Mohan Chilakala, Hanumantha Rao Kamma, Janos Vaczi
  • Co-spray drying of meropenem and colistin and the uses thereof
    Patent number: 11278497
    Abstract: The present disclosure generally relates to a process for manufacturing a dry powder composition, particularly to a co-sprayed colistin and meropenem dry powder inhaler for the treatment of various bacterial infections. Methods of use and composition matters are within the scope of this disclosure.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: March 22, 2022
    Assignee: Purdue Research Foundation
    Inventors: Qi Zhou, Sharad Mangal
  • Antimicrobial and cleansing composition consisting of a polymeric biguanide and EDTA
    Patent number: 11266683
    Abstract: The invention relates to a antimicrobial and cleansing composition consisting of a. a polymeric biguanide, and b. a metal ion chelating agent, and g. a solvent, wherein the ratio of a:b is between 0.75:2.25 and 1.25:2.25, or about 1:2, and optionally one or more of the following ingredients; c. a quaternary ammonium salt, d. at least one surfactant, e. a humectant and f. a gelling agent. The invention further relates to said composition for use in a treatment, prevention or reduction of a disease, disorder or condition related to microbials, or treatment, prevention or reduction of infection, or inflammation, or infected wounds, or inflamed wounds, or treatment, prevention or reduction of biofilms, or removal of necrotic tissue. A liquid flow system may be used for administration of the composition.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: March 8, 2022
    Assignee: Sunmedic AB
    Inventor: Abbas Karladani
  • Self-fueled particles for propulsion through flowing aqueous fluids
    Patent number: 11266596
    Abstract: A simple, self-propelling particle system is disclosed that can deliver a cargo through flowing aqueous solutions. This disclosure provides a non-aqueous composition comprising: (i) particles formed of a carbonate salt and having an average diameter of about 100 ?m or less; and (ii) an acid in solid form. The particles may be associated with a cargo molecule or particle. In mouse models of severe hemorrhage, the propelled particles are able to deliver a procoagulant enzyme and halt bleeding.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: March 8, 2022
    Assignees: The University of British Columbia, The General Hospital Corporation
    Inventors: Christian Kastrup, Ju Hun Yeon, James Baylis, Thomas Frederick Burke