Abstract: A transmit power supply optimization method optimizes power supply voltage to high voltage transmitters of an ultrasound imaging apparatus for each operating mode of the apparatus. The method comprises the steps of linking the operating mode of the apparatus, the output of the high voltage transmitters, and the power supply. It is then determined when a change in optimum power supply voltage will be desired. Operation of the high voltage transmitter power supply and the high voltage transmitters is coordinated to react to the determination that a change in optimum power supply voltage will be desired, before the change in optimum power supply voltage is actually desired. Finally, a distributed power supply filter is provided to allow the high voltage transmitters to operate while the change in optimum power supply voltage is occurring.