Abstract: The present invention relates to a continuous glucose monitoring system that is capable of continuously monitoring blood glucose levels. According to the present invention, the continuous glucose monitoring system includes: a body (A) attached to a given region of a user's body having less pain; a glucose sensor (B) having a micro needle (B1) protruding from one surface of the body (A) to be inserted into the epidermis of the user's body; and a glucose monitoring module (C) for monitoring the glucose from the glucose sensor (B).

Abstract: A method of determining glucose values during continuous glucose monitoring (CGM) measurements includes providing a CGM device including a sensor, a memory, and a processor; applying a constant voltage potential to the sensor; measuring a primary current signal resulting from the constant voltage potential and storing the measured primary current signal in the memory; applying a probing potential modulation sequence to the sensor; measuring probing potential modulation current signals resulting from the probing potential modulation sequence and storing measured probing potential modulation current signals in the memory; determining an initial glucose concentration based on a conversion function and a measured probing potential modulation current signal; determining a connection function value based on the primary current signal and a plurality of the probing potential modulation current signals; and determining a final glucose concentration based on the initial glucose concentration and the connection functio

Abstract: A method of determining glucose values during continuous glucose monitoring (CGM) measurements includes providing a CGM device including a sensor, a memory, and a processor; applying a constant voltage potential to the sensor; measuring a primary current signal resulting from the constant voltage potential and storing the measured primary current signal in the memory; applying a probing potential modulation sequence to the sensor; measuring probing potential modulation current signals resulting from the probing potential modulation sequence and storing measured probing potential modulation current signals in the memory; determining an initial glucose concentration based on a conversion function value and the primary current signal; determining a connection function based on the primary current signal and a plurality of the probing potential modulation current signals; and determining a final glucose concentration based on the initial glucose concentration and the connection function value.

Abstract: A method of filtering a signal in a continuous analyte monitoring (CAM) system includes applying time-varying filtering to the signal using a time-varying filter to generate a filtered continuous analyte monitoring signal during an analyte monitoring period. Other methods, apparatus, continuous analyte monitoring devices, and continuous glucose monitoring devices are also disclosed.

Abstract: A method for controlling sub-acute ruminal acidosis (SARA) in a dairy cow. The method includes placing a pH sensor in a rumen of the dairy cow, obtaining pH data of the rumen utilizing the pH sensor, receiving the pH data by one or more processors, calculating a first average of the pH data and a second average of the pH data utilizing the one or more processors, generating a plurality of pH classes based on a plurality of predefined pH ranges, generating a plurality of sodium bicarbonate classes based on a plurality of predefined sodium bicarbonate mass ranges, designing a fuzzy control system based on a set of rules, and determining an amount of sodium bicarbonate to add to a water supply of the dairy cow utilizing the fuzzy control system based on the first average and the second average.

Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally moved by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.

Abstract: Multi-state engagement with continuous glucose monitoring (CGM) systems is described. Given the number of people that wear CGM systems and because CGM systems produce measurements continuously, a platform that provides a CGM system may have an enormous amount of data. This amount of data is practically, if not actually, impossible for humans to process. In implementations, a CGM platform includes a data analytics platform that obtains packages of glucose measurements provided by a CGM system and also obtains additional data associated with a user. The data analytics platform generates state information for the user by processing these CGM packages and the additional data, at least in part, by using one or more models. Based on this state information, the data analytics platform controls communication with the user, which may include generating intervention strategies to prevent users from transitioning to a negative state such as discontinuing use of the CGM system.

Abstract: An inserter apparatus (e.g., a continuous analyte monitoring inserter apparatus) includes an outer member; an inner member; a transmitter carrier configured to support a transmitter and biosensor assembly during insertion of a biosensor, the transmitter carrier including a bias member; and a pivot member configured to pivot at times relative to the transmitter carrier and support an insertion device during biosensor insertion. The outer member is configured to press the bias member against the pivot member during insertion of the biosensor. During a first stroke portion of the insertion apparatus, the pivot member is prevented from pivoting. In a second stroke portion, pivoting is allowed, and the bias member causes, pivoting of the pivot member and retraction of the insertion device. Other systems and methods embodiments are provided.

Abstract: An eyewear device, method for use with an eyewear device, and a non-transient computer readable medium for detecting blood sugar levels are disclosed. The eyewear device has a frame including a first rim configured to support a first lens, a second rim configured to support a second lens, and a bridge connecting the first rim to the second rim. The bridge is configured to receive a nose of a user when the eyewear device is worn by the user. Blood sugar levels are detected by monitoring behavior of a pupil of an eye of the user with a sensor, comparing the monitored behavior with known blood sugar level behaviors, identifying a match responsive to the comparison between the monitored behavior and one of the known blood sugar level behaviors corresponding to a particular blood sugar level, and selecting the particular blood sugar level as a blood sugar level of the user.

Abstract: A continuous glucose monitoring (CGM) device may include a wearable portion having a sensor configured to produce glucose signals from interstitial fluid, a processor, a memory and transmitter circuitry. The memory may include a pre-determined gain function based on a point-of-interest glucose signal and glucose signals measured prior to the point-of-interest glucose signal. The memory may also include computer program code stored therein that, when executed by the processor, causes the CGM device to (a) measure and store a plurality of glucose signals using the sensor and memory; (b) for a presently-measured glucose signal, employ the plurality of previously-measured glucose signals stored in the memory and the pre-determined gain function to compute a compensated glucose value; and (c) communicate the compensated glucose value to a user of the CGM device. Numerous other embodiments are provided.

Abstract: A medical temperature monitoring system includes an electrical wire set having a thermistor at a distal end of the wire set configured to sense temperatures to which the thermistor is exposed; an electronic circuit in electrical communication with the wire set and the thermistor and configured to convert the temperatures sensed by the thermistor to temperature display signals; a display in electrical communication with the electronic circuit for receiving the temperature display signals and displaying temperatures corresponding to the temperature display signals; and a bead of cured protective material encapsulating the thermistor. The protective material is a radiation curable adhesive applied to the thermistor in an uncured state and then cured to encapsulate the thermistor. The bead of cured protective material electrically isolates the conductor sufficient to pass a Hi-Pot test at 500 VAC, <0.1 mA.

Abstract: Recommendations based on continuous glucose monitoring (CGM) are described. Given the number of people that wear CGM systems and because CGM systems produce measurements continuously, a platform that provides a CGM system may have an enormous amount of data. This amount of data is practically, if not actually, impossible for humans to process. In implementations, a CGM platform includes a data analytics platform that obtains glucose measurements provided by a CGM system and also obtains additional data associated with a user. The data analytics platform processes these measurements and the additional data to predict a health indicator by using models. This prediction serves as a basis for generating a recommendation, such as a message recommending the user take action or adopt a behavior to mitigate a predicted negative health condition.

Abstract: Introduced here is a digital pill comprised of a capsule, an ingestible sensor, and a slot antenna. The ingestible sensor can be configured to generate a signal indicative of a characteristic of the living body in which the digital pill is located. Biometric data can be stored, at least temporarily, in a memory in the form of signal values. For example, the slot antenna may transmit biometric data to a computing device across a network on a periodic basis (e.g., every 5 minutes, 15 minutes, 60 minutes, etc.). Alternatively, the slot antenna may stream biometric data to a computing device across the network in real time.

Abstract: A sensor inserter for a physiological characteristic sensor includes a housing that defines a track system that extends from a bottom of the housing toward a top of the housing. The sensor inserter includes a striker assembly movable relative to the housing between a first state, a second, cocked state and a third, disposal state. The striker assembly is movable from the second, cocked state to the third, disposal state to couple the physiological characteristic sensor to an anatomy. The striker assembly includes a lock beam that engages with the track system as the striker assembly moves between the first state, the second, cocked state and the third, disposal state. In the third, disposal state the lock beam inhibits movement of the striker assembly from the third, disposal state to the first state.

Abstract: The present disclosure relates to a method and system for processing a photoplethysmogram (PPG) signal to improve accuracy of measurement of physiological parameters of a subject. The method may include removing a baseline drift from the PPG signal; obtaining a drift removed signal; filtering the drift removed signal; obtaining a filtered signal; performing motion artifact correction on the filtered signal; and obtaining a corrected signal.

Abstract: A method for generating a filtered EMG signal includes obtaining a combined signal, wherein the combined signal comprises an ECG signal and an EMG signal. A first high pass filter is applied to the combined signal and an ECG model signal is generated, based on the high pass filtered combined signal. The method further includes, generating a partially filtered EMG signal by subtracting the ECG model from the high pass filtered combined signal. A second high pass filter is then applied to the partially filtered EMG signal to generate a second EMG signal and to the ECG model signal to generate a second ECG model signal. A filtered EMG signal is generated based on the second EMG signal and the second ECG model by way of a gating technique.

Abstract: An information processing apparatus of the invention is configured to: determine whether or not first biological information of a measurement subject meets a first condition, the first biological information being measured in a first period; determine, when the first biological information meets the first condition, whether or not a number of times, by which the first biological information meets the first condition with respect to the measurement subject, exceeds a first value; select a first message when the first value is not exceeded; select a second message when the first value is exceeded.

Abstract: Computer-implemented methods of enabling an on-the-fly generation of at least one user-defined montage from EEG electrodes positioned in a patient's brain, on the patient's brain and/or on the patient's scalp. The methods includes generating a graphical interface to display a view of the patient's brain and/or scalp overlaid with the EEG electrodes, each of which is uniquely identified with reference to its position in the patient's brain, on the patient's brain and/or on the patient's scalp, displaying a tool within the graphical interface for selecting at least one electrode from the displayed EEG electrodes, indicating a reference electrode corresponding to the selected electrode, accessing EEG signals corresponding to the electrode and the reference electrode, and generating another graphical interface to display an EEG trace indicative of a comparison of EEG signals of the electrode and the reference electrode.

Abstract: Disclosed is an apparatus for measuring bio signals. The apparatus for measuring bio signals includes: a sensor module configured to include a needle sensor to be inserted into the skin; and a main body to which the sensor module is separably coupled, and which is configured to include a controller controlling the sensor module to measure a bio signal through the needle sensor, once the sensor module is coupled.