Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

Abstract: In some embodiments, a method includes delivering to a native valve annulus (e.g., a native mitral valve annulus) of a heart a prosthetic heart valve (200) having a body (242) expandable from a collapsed, delivery configuration to an expanded, deployed configuration. The method can further include, after the delivering, causing the prosthetic heart valve to move from the delivery configuration to the deployed configuration. With the prosthetic heart valve in its deployed configuration, an anchoring tether (191) extending from the prosthetic heart valve can be secured to a wall (Vw) of the heart (H). An electrode (189) coupled to at least one of the prosthetic heart valve or the anchoring tether can then be used to at least one of pace the heart or sense a signal associated with the heart.

Abstract: System for filtering cardiac signals. The system includes: cardiac terminals (10a-d) adapted to collect cardiac electrophysiological potentials from a plurality of cardiac electrodes (1a-d) placed at respective cardiac locations in or on an individual (99) and a processor device (40) adapted to process one or more input signals, which are based on the collected electrophysiological potential(s). The processing includes running an adaptive filter algorithm on one or more signals based on the input signals. The adaptive filter algorithm is arranged to calculate estimated noise component(s) of the signals and arranged to subtract the estimated noise component(s) from the signals. In this way a cardiac signal is derived where the noise has been significantly reduced.

Abstract: An improved laser-therapy device for the treatment of acupuncture points, which comprises: a control unit; laser emitting means associated to said control unit; means for generating an emission signal, which are functionally associated to said control unit and to said laser emitting means; and means for modulating said emission signal, which are designed to generate a modulated signal, wherein said modulated signal derives from a first square-wave modulation at a frequency of 100 Hz combined with a second square-wave modulation at a frequency of between 1 and 2 Hz, characterized in that a third square-wave modulation at a frequency of between 50 and 200 Hz is provided, combined, respectively, with said first and second modulations, characterized in that a third square-wave modulation at a frequency of between 5 and 20 Hz is provided, combined, respectively, with said first and second modulations.

Abstract: A low-frequency treatment device and a treatment system with enhanced user convenience. An acquisition unit acquires an atmospheric pressure of a position where the low-frequency treatment device is located (step S102), a determination unit determines whether the atmospheric pressure is less than a threshold (step S104), and a treatment portion increases an intensity of low frequency treatment if the atmospheric pressure is less than the threshold (step S108).

Abstract: Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device determines a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a patient. The medical device may control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters. The medical device may further determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of the electrical activity entrained by the entrainment stimulation pulses. The medical device may subsequently control the stimulation generator to generate the desynchronization stimulation pulse(s) according to the second set of stimulation parameters.

Abstract: A magnetic-resonance-imaging-compatible (MRI-compatible) cardiac defibrillator includes: a defibrillator generator; first and second electric wires, each being electrically connected to said defibrillator generator; first and second defibrillation pads, each being electrically connected to a respective one of said first and second electric wires; and a low pass filter electrically connected between said defibrillator generator and said first and second electric wires to prevent a noise in an MRI image caused by a radiofrequency interference from the defibrillator as well as protect a patient and the defibrillator from MRI radiofrequency imaging signals, wherein said low pass filter has a cutoff frequency set such that differential mode noise at an MRI Larmor frequency is in an attenuated band while a system-test signal by said defibrillator generator is in a pass band of said low pass filter.