Abstract: A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
Type:
Grant
Filed:
December 21, 2021
Date of Patent:
November 22, 2022
Assignees:
TRUSTEES OF TUFTS COLLEGE, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
Abstract: A gutta-percha-silver composite with determined weight percentage and particle size, is provided. The composite exhibits electro-conductivity greater than the standard gutta-percha composites. The new material simplifies root canal treatments, shortens the times both for clinician and patients, and reduces the exposure to patients from X-rays. The material is not only electro-conductive; it is anti-bacterial, which improves the outcomes of the procedures. Also, it has improved thermal conductivity, and mechanical properties.
Type:
Grant
Filed:
October 6, 2016
Date of Patent:
November 1, 2022
Assignee:
THE UNIVERSITY OF HONG KONG
Inventors:
Fabio Savoldi, Jukka Pekka Matinlinna, Kit Hon James Tsoi, Corrado Paganelli, Luca Visconti, Giovanni Rasia Dal Polo
Abstract: A resin composition for a modeling material for use in shaping a modeling material (4) by an ink-jet photofabrication method, the resin composition comprising, based on 100 parts by weight of the whole resin composition, 19 to 49 parts by weight of a water-insoluble monofunctional ethylenically unsaturated monomer (A), 15 to 50 parts by weight of a di- or more-functional polyfunctional ethylenically unsaturated monomer (B), 10 to 45 parts by weight of an oligomer (C), and a photopolymerization initiator (D). By this resin composition for a modeling material, a photofabrication product having good dimensional accuracy can be obtained.
Abstract: In one aspect, the present disclosure relates to a contact lens comprising a disclosed lubricious surface layer. In a further aspect, the lubricious surface layer comprises a polyacrylamide, e.g., a poly(N,N-dimethylacrylamide. In various aspects, the lubricious surface layer is formed at the surface of a contact lens. In a further aspect, the lens can be a hydrogel lens. In a further aspect, the lens can be a silicone hydrogel lens. The present disclosure also pertains to methods of forming the disclosed lubricious surface layers on a surface of a contact lens. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
October 25, 2022
Assignee:
University of Florida Research Foundation, Inc.
Abstract: A method for producing an optical component resin, suppressing yellowing due to addition of an ultraviolet absorber, an optical component resin, a spectacle lens, and spectacles. A method for producing an optical component resin, including a step of polymerizing a polymerizable composition containing a polythiol component, a polyisocyanate component, and an ultraviolet absorber, in which the ultraviolet absorber has a Hazen color number (APHA) of 40 or less in a toluene solution thereof having a concentration of 10% by mass, an optical component resin obtained by the producing method, an optical component formed of the optical component resin, a spectacle lens including a lens substrate formed of the optical component resin, and spectacles including the spectacle lens.
Abstract: Disclosed are polymerizable compositions for ophthalmic lenses. The compositions employ peroxide-based polymerization initiators with decreased capacity for dye degradation. The compositions enable the inclusion of color-balancing dyes, resulting in lenses with improved clarity and color balance.
Type:
Grant
Filed:
March 27, 2018
Date of Patent:
October 25, 2022
Assignee:
Essilor International
Inventors:
Tipparat Lertwattanaseri, Pierre Fromentin
Abstract: An object of the present invention is to provide a two-paste type dental resin-reinforced glass ionomer cement composition which exhibit high surface curability even under wet conditions, which makes difficult for the surface to become cloudy even if moisture comes in contact with at the initial stage of curing, exhibits high mechanical properties, low water absorption expansion and excellent coloring resistance in the set product and is also excellent in storage stability.
Type:
Grant
Filed:
March 25, 2020
Date of Patent:
October 25, 2022
Assignee:
SHOFU INC.
Inventors:
Jun Uchida, Tomohiro Kumagai, Ken Hiratsuka
Abstract: A polymerizable composition for an optical material includes a compound represented by General Formula (1) and a polymerization reactive compound.
Abstract: The invention relates to urea- and/or urethane-substituted amides of the general formula (I) The radicals R1, Z1, R2, and Z2 comprise a building block containing urea groups and/or containing urethane groups; the radicals R4, Z4, R5, and Z5 comprise a building block containing amide groups, and E is a carboxylic acid group or salt thereof. The invention also relates to rheology control agents which consist of or comprise the amides of the formula (I). A further subject of the invention is a method for producing the rheology control agents, and the use of the urea- and/or urethane-substituted amides, and also of the rheology control agents, as thickeners, especially in liquid compositions, and also the liquid compositions themselves.
Abstract: The present disclosure provides systems and methods for making a hydrogel comprising a cell, cell nucleus, or one or more components derived from a cell or cell nucleus. A method for making a hydrogel may comprise providing a cell or cell nucleus, a first polymer, wherein the first polymer comprises a plurality of first crosslink precursors, each of the plurality of first crosslink precursors comprising an azide group; providing a second polymer, wherein the second polymer comprises a plurality of second crosslink precursors, each of the plurality of second crosslink precursors comprising an alkyne group; and crosslinking the first polymer and the second polymer via a reaction between a first section of the first crosslink precursors and a second section of the second crosslink precursors, thereby providing the hydrogel comprising the cell or cell nucleus.
Type:
Grant
Filed:
September 1, 2020
Date of Patent:
September 13, 2022
Assignee:
10x Genomics, Inc.
Inventors:
Joshua Delaney, Shalini Gohil, Christopher Hindson, Adam Lowe, Andrew D. Price, Joseph Francis Shuga
Abstract: According to one aspect of the present invention, a dental filling material is manufactured by surface-treating an inorganic filling material with a silane coupling agent having an epoxy group and then by causing a ring-opening reaction with a composition containing an epoxide having a (meth)acryloyl group.
Abstract: Provided are a resin material that is superior in coating appearance and adhesion to substrates and can be used not only under organic solvent-diluted conditions but also under aqueous solvent-diluted conditions; an undercoat agent for an inorganic-material thin film containing the same; and a molded body produced by using the undercoat agent for an inorganic-material thin film. Provided are a (meth)acryloyl group-containing acrylic-modified alkyd resin, an active-energy-ray-curable resin composition containing the same, the undercoat agent for an inorganic-material thin film, and a molded body produced by using the undercoat agent for an inorganic-material thin film.
Abstract: Provided are a monomer which can provide a cured product having both high toughness and rigidity, a monomer composition containing the monomer, the monomer composition used as a dental material monomer composition, a dental material composition containing the monomer composition or the dental material monomer composition, a cured product thereof having excellent mechanical properties, a dental material formed by curing the dental material composition, a method for producing the monomer composition, and a method for producing the dental material. A (meth)acrylate (D) is a reaction product of an amine compound (A) having two or more amino groups, an iso(thio)cyanate compound (B) having two or more iso(thio)cyanato groups, and a hydroxy (meth)acrylate compound (C) having one or more polymerizable groups.
Abstract: The present invention relates to an injection molded article comprising: i) 27% to 87% by weight based on the total weight of the components i to iv of a polyester constructed from aliphatic dicarboxylic acids and aliphatic diols; ii) 3% to 15% by weight based on the total weight of the components i to iv of an aliphatic-aromatic polyester comprising: ii-a) 30 to 70 mol % based on the components ii-a to ii-b of a C6-C18-dicarboxylic acid; ii-b) 30 to 70 mol % based on the components ii-a to ii-b of terephthalic acid; ii-c) 99 to 100 mol % based on the components ii-a to ii-b of 1,3-propanediol or 1,4-butanediol; ii-d) 0% to 1% by weight based on the components ii-a to ii-c of a chain extender and/or branching agent; iii) 0% to 35% by weight based on the total weight of the components i to iv of polylactic acid; iv) 10% to 35% by weight based on the total weight of the components i to iv of at least one surface-modified silicate selected from the group consisting of: kaolin, muscovite, montmorillonite, tal
Type:
Grant
Filed:
August 9, 2018
Date of Patent:
August 2, 2022
Assignee:
BASF SE
Inventors:
Maximilian Lehenmeier, Martin Bussmann, Norbert Effen, Johannes Klaus Sprafke, Gabriel Skupin
Abstract: The present invention provides a two-paste dental curable composition achieving clinically acceptable bond durability to dental adherends including dental glass ceramic restorations (particularly lithium disilicate-containing glass ceramic restorations) without using conventionally used primers. The present invention relates to a two-paste dental curable composition comprising: a first agent comprising a polymerizable monomer (a) having an acid group, a polymerizable monomer (b) having no acid group, a polymerization initiator (c), and a filler (d); and a second agent comprising a polymerizable monomer (b) having no acid group, at least one filler (e) selected from the group consisting of a basic glass filler and alumina, a polymerization accelerator (f), and a silane coupling agent (g) represented by the following general formula [I]: (The definitions of the symbols are omitted.
Abstract: Doubly-crosslinked hydrogel polyHIPEs (DC-PHs), which exhibit rapid water absorption, enhanced mechanical properties, and shape memory behavior, are provided herein, as well as processes of producing the same and uses thereof. DC-PHs comprise a continuous HIPE-templated doubly-crosslinked hydrogel, formed from hydrogel-forming monomers, ligand-bearing monomers, and crosslinking monomers.
Type:
Grant
Filed:
January 21, 2020
Date of Patent:
August 2, 2022
Assignee:
Technion Research & Development Foundation Limited
Abstract: Barrier films are prepared from a composition comprising 1) a blend of two high density polyethylene HDPE blend components, 2) zinc glycerolate and 3) a dispersion aid/synergist. The two high density polyethylene blend components have substantially different melt indices. It is difficult to properly mix the zinc glycerolate into this HDPE blend. The use of the dispersion aid/synergist improves the water vapor transmission rate (WVTR) of polyethylene film (in comparison to barrier films made with zinc glycerolate, in the absence of the dispersion aid/synergist). The resulting barrier films are suitable for the preparation of packaging for dry foods such as crackers and breakfast cereals.
Type:
Grant
Filed:
November 13, 2019
Date of Patent:
August 2, 2022
Assignee:
NOVA CHEMICALS (INTERNATIONAL) S.A.
Inventors:
Derek Wasylenko, Owen Lightbody, Tony Tikuisis, P. Scott Chisholm
Abstract: A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.
Type:
Grant
Filed:
October 1, 2020
Date of Patent:
July 19, 2022
Assignee:
Johnson & Johnson Vision Care, Inc.
Inventors:
Donnie J. Duis, Yongcheng Li, Leilani K. Sonoda, Holly L. Grammer
Abstract: The invention relates to the use of at least one compound of the formula (1) herein R1, R2 and R3 are the same or different and denote a C1-C10-alkyl as a hydrolysis stabilizer in polyester materials.
Type:
Grant
Filed:
April 26, 2017
Date of Patent:
July 12, 2022
Assignee:
Clariant Plastics & Coatings Ltd
Inventors:
Karen-Alessa Wartig, Jan-Erik Wegner, Mirco Groeseling, Juergen Wolf