Abstract: Disclosed is a magnetic-piezoelectric micro robot capable of a hyperthermia treatment, an electrotherapy and a cell therapy. The magnetic-piezoelectric micro robot includes a body and a stimulus generating layer formed at a surface of the body including a magnetic particle and a piezoelectric particle and generating heat from the magnetic particle and generating an electrical stimulus from the piezoelectric particle by an external stimulus, wherein one of a hyperthermia treatment by the magnetic particle or an electrotherapy by the piezoelectric particle is performed or both are performed simultaneously.

Abstract: The present invention promotes the activation of various physiological functions according to the stimulation of the body by superimposing a reference wave microcurrent of a low frequency and a main wave microcurrent of a high frequency into a preset pattern, or by additionally superimposing a multiple superimposed wave microcurrent discretely having a frequency of a larger magnitude sequentially than the main wave microcurrent and applying it to living organisms, and enables that the use and expandability can be increased by providing an additional configuration in which a multifunctional portable housing that can select AC electric stimulation and DC electric stimulation is worn on the wrist of the human body, thereby enabling the application of an electrical stimulation tailored to the body or disease/health condition of a user.

Abstract: Transcardiac diaphragmatic stimulation includes detecting a cardiac event based on signals sensed through a cardiac event sensor located in or on a region of a heart in proximity to a diaphragm, and delivering an ADS therapy through an ADS therapy mechanism that is located in proximity with the region of the heart, to induce a contraction of the diaphragm without inducing a contraction of the heart. The cardiac event sensor may be located a) on an interior surface of a cardiac wall that abuts the diaphragm, or 2) on an exterior surface of the heart, between a cardiac wall and the diaphragm. The ADS therapy mechanism may be located: a) on an interior surface of a cardiac wall that abuts the diaphragm, 2) on a superior surface of the diaphragm that abuts a cardiac wall, or 3) on an inferior surface of the diaphragm at a region of the diaphragm that abuts the heart.

Abstract: Provided herein are methods of generating a biologically effective unipolar nanosecond electric pulse by superposing two biologically ineffective bipolar nanosecond electric pulses and related aspects, such as electroporation and/or therapeutic applications of these methods to non-invasively target electrostimulation (ES) selectively to deep tissues and organs.

Abstract: Electrostimulation systems and methods are contemplated in which a high current level, charge balanced alternating current electrical signal is generated for delivery to the frontal cortex region of a patient's brain. By stimulating this region of the brain with a charged balanced stimulation current with a stimulation current envelope defining one or more series of pulses at particular frequencies and durations designed to evoke metabolic response in the neurons, significant improvements in efficacy and reductions in patient discomfort may be achieved relative to earlier methods of transcranial electrical stimulation, especially those in which result in a resultant rectified direct current component being administered to the patient.

Abstract: A method, apparatus and a system for thermally-assisted pulsed electromagnetic field stimulation for treatment of osteoarthritis in the knee are disclosed. A multi-coil applicator is adapted for positioning around the knee. A first coil is positioned on the top of the knee and provides electric field stimulation in the plane of the patella to stimulate the patella cartilage. Second and third coils are rectangular coils wrapped up below and above the knee respectively. The coils in the wrapped position generate a magnetic field along the knee axis and provide high amplitude of the electric field stimulation of the femoral and tibial cartilages in the plane of tibial plateau. Resistive heaters and free wheel diodes can be provided to the applicator to supply uniform thermal stimulation around the knee joint.

Abstract: Described herein are techniques to ensure a user using an external device is authorized to connect and connecting to a correct implantable medical device using a wireless communication protocol. A request for authorization is sent to the external device from the implantable medical device, and the authorization can be provided by an authorization pulse sent using the implantable medical device charger over the inductive link between the charging device and the implanted device. The authorization pulse can be trusted because the inductive link is short range, ensuring the patient is aware of the connection to the implanted device. Once the implanted device receives the authorization pulse, it may finalize the pairing over the first connection.

Abstract: Technologies and implementations for a defibrillator electrode having communicative capabilities are generally disclosed.

Abstract: A catheter pump is disclosed. The catheter pump can include an impeller and a catheter body having a lumen in which waste fluid flows proximally therethrough during operation of the catheter pump. The catheter pump can also include a drive shaft disposed inside the catheter body. A motor assembly can include a chamber. The motor assembly can include a rotor disposed in the at least a portion of the chamber, the rotor mechanically coupled with a proximal portion of the drive shaft such that rotation of the rotor causes the drive shaft to rotate, the rotor including a longitudinal rotor lumen therethrough. The motor assembly can also comprise a stator assembly disposed about the rotor. During operation of the catheter pump, the waste fluid flows from the lumen into the chamber such that at least a portion of the waste fluid flows proximally through the longitudinal rotor lumen.

Abstract: A method, apparatus, and system for determining a correspondence of physiological data obtained in a physiological study of a subject. The method includes extracting a first signal from the physiological study. A second signal from the physiological study is also extracted. The first signal and the second signal are obtained by one or more biometric sensors. Data of the first signal and data of the second signal are stored on a memory storage. A coherency value is determined between components of the extracted first signal and components of the extracted second signal. And the correspondence of the physiological study data is determined based on the determined coherency value.

Abstract: Systems, devices, and methods for electrically stimulating peripheral nerve(s) to treat various disorders are disclosed, as well as signal processing systems and methods for enhancing device monitoring protocols and detecting abnormal patient usage of the device.

Abstract: An apparatus for measuring an electrocardiogram and storing an electrocardiogram signal merged with a user input includes: a signal detector outputting an electrocardiogram analog signal by detecting an electrical signal from the heart of an object; a signal converter receiving the electrocardiogram analog signal and converting the electrocardiogram analog signal into an electrocardiogram digital signal; an input unit receiving at least one type of user input from among a voice input, a button input, a touch input, and a motion input; a processor receiving the user input, merging the electrocardiogram digital signal with the user input, and storing the electrocardiogram digital signal in an internal memory; and a communicator communicating with an external terminal to transmit the electrocardiogram digital signal to the external terminal.

Abstract: Systems and techniques for remote medical monitoring. In one implementation, a method includes monitoring a first medical condition of an individual, the monitoring being initiated remotely by a monitoring service, receiving a query relating to a second medical condition of the individual, transmitting a response to the query to the monitoring service, receiving a prompt from the monitoring service, and transmitting a response to the prompt to the monitoring service. The query is received from the monitoring service. The prompt is designed to provoke a particular action.

Abstract: A medical device including an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The medical device may further include an end-effector disposed at the distal end of the elongate member. The end-effector may include a plurality of arms pivotally connected to one another, wherein each arm includes a tissue-contacting surface, a first portion of the tissue-contacting surface including a plurality of ridges configured to grasp tissue. Further, the tissue-contacting surface may include a channel oriented substantially parallel to a longitudinal axis of the medical device.

Abstract: Disclosed are methods and compositions for preventing or disrupting mitosis of pluripotent stem cells, killing pluripotent stem cells, preventing or disrupting division of pluripotent stem cells, reducing the viability of pluripotent stem cells, slowing the progression or differentiation of pluripotent stem cells, and treating an ectopic pregnancy.

Abstract: An interface pressure sensor includes a fluid pressure sensor disposed in a volume defined by a shear wall. The volume is enclosed, and the fluid pressure sensor is encapsulated by, an infill material. The infill material defines a sensing surface that, when pressed, can impart a force that is detectable by the fluid pressure sensor. The interface pressure sensor can be used for applanation tonometry.

Abstract: A system and method are provided that include a power supply having positive and negative terminals. The negative terminal defines a reference ground. First and second electrodes are positioned within a patient and configured to be located proximate to tissue of interest that is associated with a target region. A control circuit is configured to control delivery of current for a therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.

Abstract: An example method is performed by a computing device executing instructions stored in data storage, and includes receiving physiologic monitoring data from a plurality of sensors coupled to a patient, receiving information indicating a measurement of patient motion during the patient care event, determining whether the measurement of patient motion is above a threshold, based on determining whether the measurement of patient motion is above the threshold, generating, for the physiologic monitoring data, a respective quality indicator, analyzing, by the computing device, (i) a combination of the physiologic monitoring data from the plurality of sensors and (ii) the respective quality indicator for the physiologic monitoring data to generate a response dependent upon the combination of the physiologic monitoring data as weighted by the respective quality indicator, and based on analyzing, outputting caregiver feedback by the computing device according to the response.

Abstract: The present disclosure describes an apparatus and method for alternating electric fields therapy using an optimization algorithm, and an apparatus for alternating electric fields therapy for treating tumors in a patient by applying electric fields to the tumors and normal tissues using one or more pairs of electrode pads containing most of the electrodes and including an image classifier to classify at least one organ in the patient's image for each organ, and an electric field optimizer to set the number and position of the applied electrodes based on the classified tumors and normal tissues, arrange the electrodes on electrode pads of preset size, and determine different magnitudes of voltage for the set of electrodes.

Abstract: Provided are methods and devices for treating skin conditions using an electrical signal applied to the skin of a subject.