Abstract: An insecticide composition is isolated from Paeonia suffruticosa, Cnidium officinale, Cinnamomum cassia, mustard (Brassica juncea) and horseradish (Cholearia aroracia) by using methanol or by elution with a solvent including hexane and ethyl acetate. The composition can be used to eradicate house dust mites and insects found in stored products.
Type:
Grant
Filed:
August 28, 2001
Date of Patent:
February 15, 2005
Inventors:
Young-Joon Ahn, Young-Soo Kim, Soon-Il Kim, Hyun-Kyung Kim
Abstract: An antimicrobial composition and more particularly a germicidal spray for sanitizing and disinfecting surfaces including leather, wood, metal, plastic and fabric, comprises a mixture of essential oils capable of being dissolved or dispersed by a solvent in a water carrier, oils and an ionizing agent such as Blue Stone ions which speeds up the antimicrobial activity of the essential oils. The product of the invention is completely natural and non-toxic to adults and children even if swallowed.
Type:
Grant
Filed:
November 13, 2001
Date of Patent:
January 25, 2005
Assignee:
Scentsible Life Products, a divison of Laid Back Designs Ltd.
Abstract: A herbal healing lotion in the form of a topical composition for relieving dermatological skin conditions encountered by animals. The composition is topically applied to an affected area of skin of the animal. The topical composition contains a vehicle for distributing the active ingredients to the affected skin. The vehicle is comprised of water, carboxymethylcellulose, and colostrum which allows for the active ingredients to be received by the skin on surface and deep tissue layers. The herbal healing lotion contains no steroid or antibiotic component thereby preventing immunosuppression generally associated therewith. The herbal healing lotion combines natural ingredients in a topical composition to successfully treat dermatological conditions previously held as untreatable.
Abstract: The present invention provides a method of identifying novel agents that increase glucose dependent insulin secretion in pancreatic islet cells as well as methods of treating diabetes using the agents which have an inhibitory effect on the activity of pancreatic islet cell phosphodiesterases (“PDE”) enzyme, namely PDE1C. The methods described herein are based upon the inventor's surprising discovery that inhibition of PDE1C increases glucose dependent insulin secretion. Specifically, the present invention provides for a method of identifying therapeutic agents that act to increase the release of insulin from pancreatic islet cells. The method of identification provided herein is used to determine the effects of isozyme specific phosphodiesterase inhibitors on insulin secretion from cultured pancreatic &bgr;-cells. Also provided are agents that have an inhibitory effect on the activity of PDE1C in pancreatic cells.
Type:
Grant
Filed:
February 27, 2002
Date of Patent:
November 2, 2004
Assignee:
Albert Einstein College of Medicine of Yeshiva
University
Abstract: The present invention provides methods for extracting anti-apoptotic compositions from various protein isolates and/or lipid mixtures with aqueous solutions not containing organic solvents. The compositions extracted by the methods can be used for a variety of purposes, including for therapeutic, nutritional and medicinal purposes.
Abstract: A gel made of hyaluronic acid alone which is hardly soluble in a neutral aqueous solution and which keeps its shape for at least one day in a neutral aqueous solution at 25° C.
Abstract: The invention provides a new formulation of the composition comprising Flos Lonicerae Fructus Forsythiae and Radix Scutellariae. This invention also provides a method for identification with HPLC and the characteristic peaks of the compositions of said composition. The composition possesses antiviral effective, namely, inhibition of influenza virus, parainfluenza virus, herpes I virus and herpes II virus. The invention refers to a method for preparation and control of the active components of Flos Lonicerae Fructus Forsythiae and Radix Scutellariae for its biological activity. The invention also provides a unique raw materials and intermediate formulation.
Type:
Grant
Filed:
October 24, 2001
Date of Patent:
September 7, 2004
Assignee:
National Engineering Research Center for Traditional Chinese
Medicine
Inventors:
Ping Niang Shen, Ke Feng Ruan, Yu Lan Wang, Wei Yu, Wen Qing Zhang, Xiao Kun Hong, Xin Hong Wang
Abstract: A gel rehydration electrolyte composition provides a convenient and effective way of replenishing lost fluid and electrolytes. The gel rehydration electrolyte composition masks unpleasant tastes of electrolyte and is readily consumed by young children and elderly who cannot tolerate the liquid or frozen forms of electrolytes.
Abstract: A composition and method for the treatment of chronic sinusitis in which a composition containing desirable colonial bacteria is applied externally in the form of either a spray or a flush. The bacteria are selected from the genus Lactobacillus and the genus Bifidobacterium. The selected bacteria are provided in a therapeutically effective amount in a water solution.
Abstract: The present invention provides a non-toxic therapy and a novel use for Bowman Birk Inhibitor (BBI), as administered in Bowman Birk Inhibitor Concentrate (BBIC), for the treatment of autoimmune diseases in a patient, wherein the disease is characterized by chronic inflammation, such as rheumatoid arthritis; and more particularly for the treatment of those diseases that are characterized by chronic neuroinflammation and/or demyelination, such as Multiple Sclerosis (MS) and Guillain Barre Syndrome (GBS). In addition, the present invention provides methods for using BBI/BBIC to reduce, inhibit, suppress or prevent the chronic inflammation in such patients; and more particularly, to reduce, inhibit, suppress or prevent the chronic neuroinflammation and demyelination that occurs when the patient's nerve tissue is affected by the disease.
Type:
Grant
Filed:
August 31, 2001
Date of Patent:
July 27, 2004
Assignee:
The Trustees of the University of Pennsylvania
Abstract: The invention concerns the field of pharmaceutics and dietetics. More particularly, the invention concerns pharmaceutical and/or dietetic mushroom-based compositions, characterised in that they contain one or several edible mushrooms with therapeutic properties and chitosan.
Abstract: The invention provides pharmaceutical compositions comprising a protoporphyrin precursor photochemotherapeutic agent together with vascular stroma-localizing photosensitizers, optionally together with at least one surface penetration assisting agent and optionally with one or more chelating agents, and use of the same in treating disorders or abnormalities which are responsive to PDT, preferably exhibiting synergistically enhanced therapy, kits comprising same and methods of therapy and diagnosis.
Type:
Grant
Filed:
July 9, 1999
Date of Patent:
June 15, 2004
Assignee:
PhotoCure AS
Inventors:
Qian Peng, Jahn M. Nesland, Karl E. Giercksky, Johan Moan, Trond Warloe
Abstract: The invention concerns the field of biochemistry, and more precisely biological substances of vegetable origin. The invention concerns substances having non-cytotoxic biological activity, extracted from plants with CAM metabolism, such as plants of the Cactacees, Crassulacees and Saxifragacees family. The invention also concerns the method for obtaining these substances as well as compositions containing them. Said compositions are designed for accelerating and amplifying the synthesis of thermal shock proteins of cells of living beings in vivo or in vitro.
Type:
Grant
Filed:
January 25, 2002
Date of Patent:
May 18, 2004
Assignee:
INOVAT S.A.R.L.
Inventors:
Gilles Gutierrez, Mostafa Serrar, Lionel Viornery, James Norton
Abstract: An animal-derived lipid is disclosed that is useful as a carrying agent for anti-microbial formulations. Pharmaceutical and other preparations including Emu Oil are also described as profoundly useful components in anti-bacterial, anti-fungal, and anti-viral treatments. This lipid material is extracted from the Emu (Dromais Novae-Hollandiae), an indigenous bird of Australia and New Zealand. The present invention also discloses therapeutic compositions comprising Emu Oil in combination with an extracellular product of Bacillus coagulans or Pseudomonas lindbergii strain, comprising a supernatant or filtrate of said culture suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. Additionally, the aforementioned therapeutic composition may also include an anti-microbial, anti-mycotic, and/or anti-viral agent.
Abstract: An isolated and essentially purified cell matrix plaque of initial bone formation comprising of &agr;v&bgr;3 integrin and rapid assays using such cell matrix plaques to measure potentials of factors, regimens or tissues for stimulation and/or inhibition of bone formation.
Abstract: The invention provides compositions such as dietary supplements. Such compositions can be used to reduce pain, inflammation, stiffness, and/or discomfort associated with inflammatory conditions such as arthritis. The invention also provides methods for reducing pain, inflammation, stiffness, and/or discomfort associated with inflammatory conditions such as arthritis.
Abstract: A combination drug therapy is disclosed for the treatment of a patient affected with Gaucher's disease or other such glycolipid storage diseases. The method comprises administering to said patient a therapeutically effective amount of both a N-alkyl derivative of deoxynojirimycin (DNJ) and a glucocerebrosidase enzyme to alleviate or inhibit the glycolipid storage disease. The alkyl group has from about two to about 20 carbon atoms and preferably is butyl, nonyl or decyl.
Abstract: Pesticidal compositions for the control of mites in stored food products containing one or more plant essential oils. In addition, the present invention is directed to a method for controlling mites from accessing stored food products by applying a pesticidally-effective amount of the above pesticidal compositions to a locus where pest control is desired.
Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
Abstract: Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat.