Abstract: The aspects of the disclosed embodiments relate to method for determining a likelihood of an inflammatory gastrointestinal tract disease. The method includes diluting a biological sample of a human subject and contacting it with 8-anilinonaphthalene-1-sulfonic acid as modulating agent and further with a reagent, said reagent comprising a peroxidase enzyme and a label selected from a europium chloride and terbium chloride. The sample is incubated and excited, and the time-resolved luminescence signal of the label in the sample is measured. If the luminescence signal is at least 112% higher than for a control sample from a human so subject without of an inflammatory intestine disease, an increased likelihood of an inflammatory intestine disease of the human subject is determined.

Abstract: The present disclosure provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments; and methods for making and using them. Methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.

Abstract: A method of inhibiting mycotoxin growth in a site susceptible to mycotoxin contamination, comprising obtaining a Arthrospira platensis, reducing the Arthrospira platensis to nanoparticles, and dispensing the Arthrospira platensis nanoparticles to the site susceptible to mycotoxin growth. In an embodiment, the site vulnerable to mycotoxin contamination is an animal feed supply. In an embodiment, the site susceptible to mycotoxin contamination is wastewater. Use of the Arthrospira platensis nanoparticles efficiently inhibits or prevents mycotoxin contamination.

Abstract: Disclosed are methods and probiotic compositions for the treatment of a metabolic disease or disorder such as, e.g., obesity, type 2 diabetes, or fatty liver. In some embodiments, heat-inactivated Parabacteroides goldsteinii is enterically administered to a subject, such as a human patient, to treat the metabolic disease or disorder or to promote the development of warm microbiota to treat the metabolic disease or disorder. In some aspects, spermine or spermidine may be administered to a subject or used in vitro to promote the growth of microbiota that can be used for the treatment of a metabolic disease or disorder.

Abstract: A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: wherein the variables are described throughout the application.

Abstract: Described are the Bacillus subtilis strain deposited as DSM 32685 and mutant strains thereof which are susceptible to relevant antibiotics, have inhibitory activity against, for example, Staphylococcus, Streptococcus, E. coli and Salmonella, and have the ability to facilitate degradation of non-starch polysaccharides and thereby increase the amount of available oligosaccharides (sugar) in animal feed. Also described are compositions comprising at least one Bacillus subtilis strain of the disclosure and optionally further bacteria and/or one or more types of yeast and methods of using such compositions.

Abstract: Molecules secreted or derived from probiotic bacteria are provided for use in compositions and methods for the treatment and/or prevention of infection by pathogenic viruses. The isolated secreted molecules can also be used in nutritional or medical food products which provide probiotics to the gastrointestinal tract of a mammal.

Abstract: The present disclosure provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage, e.g., orthostatic lavage, e.g., for inducing the purgation (e.g., cleansing) of a gastrointestinal (GI) tract, including a colon; and methods for making and using them. Methods of the invention are used for the stabilization, amelioration, treatment and/or prevention of constipation, for the treatment of abdominal pain, particularly non-specific abdominal pain, and diarrhea, including diarrhea caused by a drug side effect, a psychological condition, a disease or a condition such as Crohn's Disease, a poison, a toxin or an infection, e.g., a toxin-mediated traveler's diarrhea, or C. difficile or the pseudo-membranous colitis associated with this infection.

Abstract: Disclosed are a tissue staining composition and a tissue staining method using the same, wherein existing staining using hematoxylin and eosin staining reagents can be shortened from two steps to one step to reduce the reagent consumption and shorten the staining time, thereby achieving fast diagnosis.

Abstract: The present invention relates to separation of desired target products from biological, plant, and waste-type material, wherein the desired target products include renewable fuels such as ethanol, biobutanol, and biodiesel, wherein the separation is conducted with a cross-flow filtration system having the ability to separate desired products from both non-viscous and viscous medium.

Abstract: The composition is an herbal supplement comprised of hydrolyzed whole soybean, Bacillus amyloliquefaciens, lactic acid bacteria, the mushroom, Auricularia polytricha, and turmeric. The soybean feeds the bacterial components of the composition to increase their biomass. The Bacillus amyloliquefaciens produces protease and amylase enzymes which hydrolyze the proteins and carbohydrates in the soybean into smaller peptides and oligosaccharides. These smaller nutrients are more easily absorbed by the gastrointestinal tract. The lactic acid bacteria are probiotics which limit the growth of Bacillus amyloliquefaciens in the composition thus balancing the gastrointestinal microbiome. The mushroom, Auricularia polytricha enhances blood flow, removes toxins from the bowel, stabilizes the digestive system and enhances digestion. Turmeric is an antioxidant, anti-ulcer, anti-bacteria (including the suppression of Helicobacter pylori bacteria), anti-inflammatory.

Abstract: A method of inhibiting mycotoxin growth in a site susceptible to mycotoxin contamination, comprising obtaining a Arthrospira platensis, reducing the Arthrospira platensis to nanoparticles, and dispensing the Arthrospira platensis nanoparticles to the site susceptible to mycotoxin growth. In an embodiment, the site vulnerable to mycotoxin contamination is an animal feed supply. In an embodiment, the site susceptible to mycotoxin contamination is wastewater. Use of the Arthrospira platensis nanoparticles efficiently inhibits or prevents mycotoxin contamination.

Abstract: A probiotic composition comprising Bacillus amyloliquefaciens, Enterococcus faecalis, Lactobacillus salivarius, Lactobacillus johnsonii, Lactobacillus gallinarum and Lactobacillus crispatus is provided. The probiotic composition stimulates the immune response of chickens without negatively affecting growth performance. The probiotic composition can be added to poultry feed to improve the health and performance of chickens, and can be used as a replacement for antibiotic supplementation.

Abstract: Disclosed herein are compositions and methods for use in treating headache.

Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.

Abstract: The invention provides methods of making and using compositions for establishing mixed chimerism in a subject that include CD34+ cells and CD3+ cells derived from an apheresis product obtained from a subject that has previously donated a solid organ.

Abstract: This invention includes the composition of a highly concentrated liquid inoculant (between 1010 and 1011 cfu/mL) for soybean crops. The composition is packed and has a shelf life of up to 2 years stored at temperatures of up to 25° C. The inoculant may be applied in low doses onto seeds or in the furrow.

Abstract: The present invention provides a method for determining whether or not a test sample contains a phytopathogenic fungi selectively from two kinds of fungi of a phytopathogenic fungus and a non-phytopathogenic fungus. The method according to the present invention comprises: (a) putting the test sample on a front surface of a substrate comprising a through hole; wherein the substrate comprises a cellulose film on the back surface thereof; the cellulose film has a thickness of not less than 0.5 micrometers and not more than 2 micrometers; and the through hole has a cross-sectional area of not less than 7.065 square micrometers and not more than 19.625 square micrometers; (b) leaving the test sample at rest; (c) observing a back surface of the film; and (d) determining that the test sample contains the phytopathogenic fungus, if a fungus is found on the back surface of the film.

Abstract: Provided are a microorganism having an ability to degrade ethanol and acetaldehyde, and a composition and a kit each including the microorganism.

Abstract: A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.