Abstract: The invention relates to aqueous compositions comprising an anionic surfactant and a hyperbranched polyesteramide having at least one quaternized amine endgroup. The compositions, in particular in the form of shampoo preparations are suited for increasing the volume of hair treated therewith. Furthermore, such compositions provide styling attributes and increase the wet-combability of hair.

Abstract: The invention provides intradialytic parenteral nutrition (IDPN) solutions with low carbohydrate for the treatment of malnutrition in dialysis patients. The IDPN solutions of the invention are particularly advantageous for the treatment of malnutrition in patients who are diabetic or suffer from other glucose management related pathologies or patients who require strict fluid management.

Abstract: Described herein are compositions comprising a MMP-13 inhibitor, and methods of using the same.

Abstract: Multi-polymer compositions for the transdermal delivery of drugs, such as amine-functional drugs, in a flexible, finite form are described. The compositions comprise a polymer matrix that includes a drug or a pharmaceutically acceptable salt thereof and a polymer matrix comprising acrylic polymer(s), polyisobutylene polymer(s) and styrene-isoprene-styrene block copolymer(s). Methods of manufacturing and methods of using the compositions also are described.

Abstract: Freshening compositions comprising a malodor binding polymer and an aqueous carrier, wherein the composition is essentially free of any material that would soil or stain fabric; and methods thereof are provided. In some embodiments, the malodor binding polymer comprises a homopolymeric polyethylenimine having a molecular weight of about 1,000 to about 2,000,000. In some embodiments, the freshening composition includes a buffering agent providing a pH of about 6 to about 8. Such freshening compositions may be used to reduce malodor and/or microbes on inanimate surfaces or in the air.

Abstract: Freshening compositions comprising a malodor binding polymer, a malodor counteractant comprising at least one aliphatic aldehyde, and an aqueous carrier, wherein the composition is essentially free of any material that would soil or stain fabric; and methods thereof are provided. In some embodiments, the malodor binding polymer comprises a homopolymeric polyethylenimine having a molecular weight of about 1,000 to about 2,000,000. Such freshening compositions may be used to reduce malodor and/or microbes on inanimate surfaces or in the air.

Abstract: The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.

Abstract: A kit for protecting keratin materials against UV radiation above 280 nm, including at least two different compositions, at least one compound (X), at least one compound (Y), and at least one hydrophobic screening system including (i) at least one hydrophobic organic sunscreen agent (A) absorbing UV radiation of 320-400 nm and at least one hydrophobic organic sunscreen agent (B) absorbing UV radiation of 280-320 nm, and optionally an inorganic sunscreen (D); (ii) at least one hydrophobic organic sunscreen (C) absorbing UV radiation of 280-400 nm, and optionally an inorganic sunscreen (D); or (iii) at least one hydrophobic organic sunscreen (A) absorbing UV radiation of 320-400 nm and either at least one hydrophobic organic sunscreen (C) absorbing UV radiation of 280-400 nm, or at least one inorganic sunscreen (D); at least one of compounds (X) and (Y) being a silicone compound.

Abstract: A method of killing and removing bacteria, mold, mildew or fungus from a surface or keratin substrate includes contacting the surface with an aqueous solution containing a multi carboxylic alpha hydroxy acid, a mono carboxylic organic acid and optionally Aloe. The aqueous solution has a pH of less than 2. The method can also be used to deodorize fabrics, surfaces or stagnant water. The method can also be used to treat wounds and skin irritations.

Abstract: This invention pertains to a choline containing composition, delivered through a delivery system, to reverse the negative effects of urine on plants, containing turf grass, ornamental flowers, shrubs and bushes. The invention also provides method to deliver choline containing products to the foliar portion of plants.

Abstract: The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+ ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more small carboxylic acid molecules as parietal cell activators in the gastric lumen. Unexpectedly, the compositions of the present invention are capable of enhancing the anti-acid activity of PPI in the stomach. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.

Abstract: The invention relates to a cosmetic method for making-up and/or caring for keratin materials, in particular the skin, whereby a cosmetic composition is applied to the keratin materials, said cosmetic composition comprising siloxane resins and fillers. In particular, the invention relates to compositions used to care for or make-up the aforementioned keratin materials.

Abstract: The invention relates to an aqueous medium containing an amino(meth)acrylate polymer or copolymer which is not soluble in dematerialised water, characterized in that the medium has a content of an aqueous phase of at least 60% by weight and a content of up to 40% by weight of solids comprising the amino(meth)acrylate polymer or copolymer, whereby the aqueous phase is charged by a sufficient amount of carbon dioxide that effects the amino(meth)acrylate polymer or copolymer to be present in solute form in the medium. The aqueous medium may be used beneficially as a coating or binding solution for the spray coating or binding of pharmaceutical compositions or nutraceutical compositions or cosmetical compositions.

Abstract: Formulations of sparingly water-soluble active ingredients, consisting of carrier particles provided with active ingredient-containing coatings, the sparingly soluble active ingredients being embedded in coatings composed of amphiphilic copolymers.

Abstract: A tablet which comprises solid particles, especially magnesium oxide particles as the main component and has excellent shape retentivity with extremely low susceptibility to wearing and chipping. The tablet has a domed shape on each of the upper and lower horizontal surfaces of a cylindrical plate shape, wherein the domed shape on each of the upper and lower horizontal surfaces satisfies the following requirements (a), (b) and (c) in the cross-sectional shape including the center line of the cylindrical plate shape: (a) each corner has an angle of 25 to 45°, (b) each corner has a horizontal length of 0.30 to 1.0 mm, and (c) the cup has a depth of 0.6 to 1.2 mm.

Abstract: Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.

Abstract: The present invention discloses a magnetic nanomedicine for inhibiting/treating human prostate cancer, which comprises a core containing a magnetic particle having a diameter of less than 10 nm; a shell made of a carboxylated polyaniline and encapsulating the core; and a medicine covalently linked to the shell and able to inhibit/treat prostate cancer. The magnetic nanomedicine of the present invention not only has superior thermal stability and but also has water solubility higher than that of the conventional anti-prostate cancer medicine. Further, the magnetic nanomedicine of the present invention can be magnetically conducted to the cancer area to increase the local concentration of medicine and enhance the therapeutic effect.

Abstract: Described herein are compositions comprising a MMP-13 inhibitor, and methods of using the same.

Abstract: Compositions and methods are provided for the manufacture and use of hydrogels with increased permeability to macromolecules with minimum loss of matrix mechanical strength and prepolymer viscosity for patternability. The hydrogels of the invention are formed from a prepolymer, which is polymerized in the presence of hydrophobic nanoparticles. In some embodiments of the invention cells are present during polymerization, and are encapsulated by the hydrogel. A high interfacial energy between the hydrophobic substrate and the aqueous polymerizing solution disrupts the hydrogel network structure, leading to network defects that increase permeability without loss of patternability.

Abstract: The invention relates to hair care compositions comprising an effective amount of a condensation polymer having at least one, optionally quarternized or protonated, dialkylamide end-group connected through the polymer backbone to a unit derived from an alkylamide, the connection comprising at least one ester linkage.