Abstract: Disclosed is a novel silver halide emulsion containing silver chloride-containing crystal grains which are cubic or rectangular parallelepiped silver halide crystals containing 30 mol % or more silver chloride on the crystal surface and surrounded mainly by (100) crystal faces, where the silver halide crystal has a projection of another crystal part formed on at least one (100) surface of the six crystal faces thereof and starting from the (100) surface has a bottom surface, the projection crystal part has substantially the same halogen composition as that of the surface of the (100) face of the original cubic or rectangular parallelepiped silver halide crystal grain, and the adjacent projection crystal parts have a groove part therebetween which is parallel to the edge part of the original silver halide crystal grain.

Abstract: A potent, selective opioid receptor agonist or antagonist exhibiting properties useful for a longacting analgesic or opiate abuse treatment agent or appetite suppressant having the general formula: ##STR1## wherein R is methyl, cyclopropylmethyl or allyl, and R.sub.1 is an unsubstituted or substituted aryl, aralkyl, heteroaryl, heteroaralkyl or a cycloalkyl group with or without a heteroatom like S,O,N; and the pharmaceutically acceptable salts thereof.

Abstract: A superhigh contrast negative type silver halide photographic material comprising a support having provided thereon at least one silver halide emulsion layer, the emulsion layer or at least one other hydrophilic colloid layer containing at least one hydrazine derivative and at least one compound of formula (I):Y[(X).sub.n A-B].sub.m (I)wherein Y represents a group capable of adsorbing to silver halide; X represents a divalent linking group comprising an atom or atoms selected from a hydrogen atom, a carbon atom, a nitrogen atom, an oxygen atom and a sulfur atom or an atomic group comprised of the atoms; A represents a divalent linking group; B represents a substituted or unsubstituted amino group, an ammonium group or a nitrogen-containing heterocyclic group; m represents 1, 2 or 3; and n represents 0 or 1. The photographic material may contain an organic desensitizer and a water-soluble rhodium salt, and the material has a low sensitivity and can be handled in a bright room.

Abstract: A silver halide photographic material is disclosed, which has high image quality in addition to high sensitivity. The photographic material comprises a support and at least one silver halide light-sensitive emulsion layer containing a compound being capable of splitting off a diffusible development-inhibitor or a precursor thereof upon a reaction with an oxidized product of a color developing agent. At least one of the silver halide light-sensitive emulsion layer layer and a layer adjacent to the light-sensitive emulsion layer contains a silver halide emulsion comprising a silver halide grain having an internal fog nucleus.