Abstract: Provided herein are methods for treating a pulmonary infection in a patient in need thereof, for example, a nontuberculous mycobacterial pulmonary infection for at least one treatment cycle. The method comprises administering to the lungs of the patient a pharmaceutical composition comprising a liposomal complexed aminoglycoside comprising a lipid component comprising electrically neutral lipids and an aminoglycoside. Administration comprises aerosolizing the pharmaceutical composition to provide an aerosolized pharmaceutical composition comprising a mixture of free aminoglycoside and liposomal complexed aminoglycoside, and administering the aerosolized pharmaceutical composition via a nebulizer to the lungs of the patient. The methods provided herein result in a change from baseline on the semi-quantitative scale for mycobacterial culture for a treated patient, and/or NTM culture conversion to negative during or after the administration period.

Abstract: The compound N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxy}butyl)octadecanamide is a useful drug compound for enhancing immune response and can be used, for example, as a vaccine adjuvant and a cancer treatment.

Abstract: The object is to provide a wrinkle improving agent having an excellent wrinkle improving effect. A compound expressed by the following Formulas (1) and/or (2) is used as an active ingredient of a wrinkle improving agent. (In Formulas (1) and (2), R and R? independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R? represents an alkylene group having 1 to 3 carbon atoms, and n represents a number of 0 or 1.

Abstract: An oral care composition comprising a local anaesthetic agent, a film-forming polymer and a non-aqueous vehicle wherein the film-forming polymer comprises an alkyl vinyl ether-maleic acid or anhydride copolymer or salt thereof is provided.

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a stannous ion source, a polyphosphate and an acid in a calcium pyrophosphate base. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

Abstract: Compositions for cosmetics containing (A) one or more kinds of N-mono long-chain acyl basic amino acids, and (B) one or more kinds of N-mono middle-chain acyl basic amino acids, and compositions for cosmetics further containing (C) an inorganic powder, provide cosmetics that give, on application, a comfortable silky feeling and, to the skin after application, a natural translucency, good luminous finish and a uniform feeling of the skin surface, and have adhesiveness to the skin and high covering power.

Abstract: Disclosed is a hair care composition comprising: a cationic surfactant system; a high melting point fatty compound; a fatty ester of benzoic acid; a non-volatile hydrocarbon oil; and an aqueous carrier. The compositions of the present invention provide conditioning benefits, especially dry conditioning benefits, while providing improved clean feel.

Abstract: An oral care composition comprising a surfactant having formula [R(OC2H4)xOSO3]2M wherein R is a saturated or unsaturated alkyl group with an alkyl chain length of 8 to 30 carbon atoms; x is from 0 to 10; and M is a divalent metal cation selected from zinc cations, copper cations and stannous cations is provided.

Abstract: In one aspect, the present invention is directed to formulations comprising at least one pressure generating vehicle along with at least one skincare active agent in a container such that the pressure generating vehicle would eject the formulation as foam, whipped cream or a similar form upon application of external pressure on the container.

Abstract: The invention discloses an oil-free additive for hair and scalp conditioning, which includes the following ingredients in percentage: 50% pure water, 5% sodium stearoyl lactylate, 10% vitamin E, 10% histidine, 1.5% anhydroxylitol, 3.5% hydrolyzed wheat protein, 7% allantoin, 5% hydrolyzed albumen and 8% carnosine. The invention has following characteristics: 1. It is the first oil-free formula in the field of hair care, so related products produced with the additive will not block hair follicles on scalps, thus leaving no residue and bringing no burden to hair care; 2. It can effectively reduce chemical damages occurred during hair perming and dyeing, and neutralize chemical residue; 3. Being non-irritating and corrosion preventing, it neutralizes residual calcium compounds in the hair, calcium carbonate and magnesium carbonate, thereby inhibiting hair splitting effectively; 4.

Abstract: Oral care compositions and methods for the same are disclosed. The oral care composition may include an orally acceptable vehicle, and one or more surfactants. The one or more surfactants may include an N-alkyl-N-acylglucamine. The oral care composition may further include an amino acid and one or more abrasives. The method for treating or reducing dentinal hypersensitivity may include contacting the oral care composition with surfaces of the teeth.

Abstract: The invention presents a fast-drying nail polish topcoat composition with high shine and long wear. The disclosed combination of at least two cellulose-derived primary film formers, a ketone-aldehyde resin, a plasticizer, a hydrocarbon oil, and solvents selected such that no more than 20% of the solvents have an evaporation rate less than or equal to butyl acetate provides a nail polish that can be dried within 30 seconds on fingernails without sacrificing other critical properties.

Abstract: The present disclosure relates to compositions suitable as leave-in hairstyling compositions comprising (a) a first polysaccharide comprising inulin; (b) a second polysaccharide comprising carrageenan; (c) a third polysaccharide; and (d) a humectant. The compositions as leave-on hair styling do not require synthetic film-forming polymers nor do they require silicones. The leave-on hair styling compositions are particularly useful in methods for imparting durable styling or shaping benefits to hair.

Abstract: The present invention provides: a method for producing a shaped product comprising octacalcium phosphate and having a volume of 2.0 mm3 or more, comprising immersing a precursor ceramic composition containing at least one of Ca and PO4 in composition, having a solubility in H2O higher than that of octacalcium phosphate, and having a volume greater than 2.0 mm3, in a solution containing a component which is not contained in the precursor ceramic composition, among the components Ca, PO4 and H2O, which are components of octacalcium phosphate to allow the precursor ceramic composition to react, thereby converting at least a part of the precursor ceramic composition into octacalcium phosphate; and the like.

Abstract: Disclosed is a skin care composition comprising starch, benzotriazole derivative sunscreen, whitening pigment and a cosmetically acceptable carrier, wherein the starch is present in amount of less than 2.2% by weight of the composition, and the benzotriazole derivative sunscreen is present in amount of less than 0.22% by weight of the composition.

Abstract: The present invention provides compositions, methods and processes for the maturation of submicron liposome compositions comprising a lipid, a sterol, and a saponin.

Abstract: The antiseptic wound dressing includes at least nanometer chitin, alkaline earth metal alginate, and an antiseptic material. The nanometer chitin is tubular shaped having diameter 10˜50 nm and length 20˜200 nm. The amount of the nanometer chitin is 0.1%˜5% to the alkaline earth metal alginate. The antiseptic wound dressing is manufactured by mixing nanometer chitin and alkaline metal alginate, further mixing with antiseptic material, conducting a wet spinning process to produce fibers, and conducting a non-woven cloth process to obtain the antiseptic wound dressing of the present invention. Therefore, the antiseptic wound dressing is capable of reducing the chance of would infection, and providing superior moisture retention and enhanced wet strength.

Abstract: A lignin-zinc oxide nanohybrid may be formed by sonication of isolated lignin derived from Phoenix dactylifera biomass in an aqueous solution of a soluble zinc salt. The lignin-zinc oxide nanohybrid emulsion or nanoemulsion may then be formed by mixing the lignin-zinc oxide nanohybrid with oil and a stabilizing surfactant and sonicating. The lignin-zinc oxide nanohybrid emulsion effectively bocks UV radiation across the UV spectrum and might therefore be used for UV protection as a sunscreen.

Abstract: A soft-focus composition comprises particles. The particles comprise a substrate with a metal oxide coating. The metal oxide coating covers from about 50% to about 75% of the surface area of the substrate. The particles have a span of from about 0.1 to about 2.1. From about 50% to about 75% of the particles are platelet shaped and the remainder are at least one different shape. This soft-focus composition can be used in cosmetic and personal care formulations to impart a soft-focus effect on the skin to hide fine lines and blemishes while allowing the natural glow of the skin to shine through.

Abstract: The present invention provides a composition comprising (i) about 0.05 to about 0.5% by weight retinol; (ii) a polar emollient selected from the group consisting of propylene glycol stearyl ether dicaprylyl carbonate, propylene glycol isostearate and combinations thereof; and (iii) isohexadecane, wherein the weight ratio of polar emollient to isohexadecane is 1:1 or lower and the composition is anhydrous.