Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.

Abstract: A patient's response to therapy such as CRT is assessed by cross correlation of a patient's evoked response and physical activity surrogates. Based on the cross correlation, a determination may be made as to whether or how much the therapy is helping the patient's physical activity. For example, the degree of cross correlation index between IEGM parameters and activity threshold parameters may be used to assess whether the patient's heart condition improves the patient's physical activity. The therapy may then be modified as necessary in the event the patient is not sufficiently responding to the therapy.

Abstract: Heart monitoring system includes implantable medical device and service center.

Abstract: An implantable medical device (IMD) including a nonhermetic battery is described. The IMD includes components and a power source module that includes the nonhermetic battery. The IMD also includes a barrier to substantially impede movement of substances from the nonhermetic battery to the components. The barrier may include a hermetic feedthrough, a gel, a polymer, or a solid electrolyte within the nonhermetic battery, and a seal member. The barrier may also be a material that encapsulates the nonhermetic battery and a getter within the IMD. In some embodiments, the IMD comprises a modular IMD including an interconnect member. In that case, the barrier may include a material that fills at least a portion of a void defined by the interconnect member. A length and a cross-sectional area of the interconnect member may also act as a barrier.

Abstract: An implantable cardiac device is configured and programmed to assess a patient's cardiopulmonary function by evaluating the patient's heart rate response. Such evaluation may be performed by computing a heart rate response slope, defined as the ratio of an incremental change in intrinsic heart rate to an incremental change in measured activity level. The heart rate response slope may then be compared with a normal range to assess the patient's functional status.

Abstract: According to one aspect, an electrical stimulation system for treating tinnitus is provided. The system includes an electrical stimulation lead adapted for implantation into the person's skull for electrical stimulation of target brain tissue located in the person's temporal lobe. The lead includes one or more electrodes adapted to be positioned near the target brain tissue and to deliver electrical stimulation energy to the target brain tissue. The system also includes a stimulation source operable to generate signals for transmission to the electrodes of the lead to cause the electrodes to deliver electrical stimulation energy to the target brain tissue located in the person's temporal lobe to reduce tinnitus effects.

Abstract: A medical electrical lead includes a proximal insulation segment, a distal insulation segment, a conductor extending within the proximal and distal segments, and an electrode coupled to the conductor and disposed in proximity to a distal end of the distal insulation segment. A fixation element of the lead is coupled to a distal end of the proximal insulation segment and includes a wire wound in a helix, which extends distally from the proximal segment, over the distal insulation segment.

Abstract: A pumping system 10, FIG. 1, provides a physiological pulsatile flow and includes controller 121, a pump drive head 50 coupled to a motor 12 and a fluid housing 52 having at least one port 60. The port 60 includes a ball valve retainer region 69, a valve seat 73, and an occluder ball 71 disposed in the ball valve retainer region 69. During operation, the motor 12 forces the fluid in and out the fluid housing 52 and causes the occluder ball 71 to move from a first position whereby the fluid cannot pass through the port 60, to a second position whereby the fluid moves annular to and generally around the occluder ball 71. This movement creates a slight flow reversal that “breaks up” any blood clots that may form. The pumping system may be used as part of a cardiopulmonary bypass system, a ventricular assist device (VAD) and/or a heart pump.

Abstract: System for transcutaneous energy transfer to an implantable medical device adapted to be implanted under a cutaneous boundary having a housing having a first surface adapted to face the cutaneous boundary, the first surface of the housing of the implantable medical device having a first mating element, therapeutic componentry and a secondary coil operatively coupled to the therapeutic componentry. An external power source has housing having a first surface adapted to be placed closest to the cutaneous boundary, the first surface of the housing of the external power source having a second mating element and a primary coil capable of inductively energizing the secondary coil when externally placed in proximity of the secondary coil. The first mating element and the second mating element are configured to tactilely align the external power source with the implantable medical device.

Abstract: A device for altering cardiac performance includes an energy absorbing element which absorbs cardiac pumping energy from at least a portion of the heart. The energy may be delivered to another part of the body, such as another portion of the heart, to perform useful work such as providing blood pumping assistance.

Abstract: Unique electrodes and/or electrical lead assemblies are provided for stimulating cardiac tissue, muscle tissue, neurological tissue, brain tissue and/or organ tissue; to electrophysiology mapping and ablation catheters for monitoring and selectively altering physiologic conduction pathways. The electrodes, lead assemblies and catheters optionally include fluid irrigation conduit(s) for providing therapeutic and/or performance enhancing materials to adjacent biological tissue. Each device is coupled to or incorporates nanotube structures or materials therein. Methods for fabricating, deploying, and operating such medical devices are also provided.

Abstract: Disclosed are systems and methods which provide management of historical information associated with a medical device, such as an implantable neurostimulation pulse generator, drug pump, cardiac device, hearing enhancement device, or vision enhancement device. Such management of historical information includes storage of historical information within an associated medical device. Historical information stored within a medical device may provide a complete summary of the use, configuration, and operation of the medical device, e.g., information spanning the entire in-service life of the medical device. Historical information for which management is provided may include both static data and dynamic data. The historical information may be used in configuring the medical device, analyzing the operation of the medical device, autonomously altering operation of the medical device, etcetera.

Abstract: An implantable medical device and associated method for automatically generating morphology templates during fast cardiac rhythms, confirming a provisional template as a confirmed template, and using the confirmed template to classify subsequent detected arrhythmias. A provisional SVT template may be created during a fast ventricular rate and activated as a confirmed SVT template upon verification that the fast rate was due to an SVT. The confirmed SVT template may be used to discriminate SVT from VT/VF.

Abstract: Medical apparatus for detecting the presence of artifact signals generated in the electrocardiogram of a patient by CPR and/or other patient motion. The presence of artifact signals is determined by analyzing variations in a measured electrical signal that represents the patient's transthoracic impedance. Such detection is important because the presence of CPR and/or motion artifacts can disrupt a patient's electrocardiogram (ECG) signal. The patient's impedance signal data is stored in the apparatus and analyzed to determine if the characteristics are indicative of the presence of CPR and/or motion artifacts. This analysis is performed independently of ECG data and may be used as an indicator of the underlying ECG rhythm classification. In essence, if the impedance exceeds some threshold amount, so as to indicate the presence of CPR or patient motion which can render the ECG data unreliable, the normal interpretation of the ECG data is interrupted.

Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.

Abstract: An implantable tissue-stimulating device comprising an elongate electrode carrier member (11) having a plurality of electrodes thereon. The electrodes are preferably disposed in a linear array on the carrier member (11) and are adapted to apply a preselected tissue stimulation to the cochlea. The carrier member (11) is preformed from a resiliently flexible biocompatible silicone and extends from a distal end (12) to a stop member (13). The carrier member (11) is adapted for intracochlear but extraluminar insertion within the cochlea of an implantee. In particular, the carrier member (11) is adapted to be implanted in the crevice (21) between the spiral ligament (22) and the endosteum (23) of the lateral wall of the cochlea (20). This is a quite different location to the normal placement of the cochlear implant electrode array in the scala tympani (24) of the cochlea (20).

Abstract: A system and method for assessing link quality for radio frequency (RF) transmissions between a programmer and an implantable medical device (IMD) is provided. An embodiment of the method includes measuring a plurality of available wireless communication channel potentially used to communicate between an implantable medical device (IMD) and a programmer to determine signal and noise levels for the channels. The method also includes storing the signal and noise levels. The method further includes processing the stored levels to determine the interference potential on the channels adjacent to the available channels. In this embodiment, the method also includes selecting a preferred communication channel based on a function of noise level for a target center channel and interference potential for corresponding adjacent channels to the target channel. Other aspects and embodiments are provided herein.

Abstract: An electrode array that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array an elongate member having a plurality of electrodes mounted thereon in a longitudinal array. A delivery cannula for delivering the electrode array comprised of two half-pipes is also described.

Abstract: A telemetry system for radio-frequency communications between an implantable medical device and an external device providing improved noise immunity is disclosed. Multiple communications channels are used to enable establishment and re-establishment of communications between a particular pair of devices in a multiple device environment.

Abstract: In one aspect of the invention, there is provided a method and apparatus for early detection of subacute, potentially catastrophic infectious illness in a premature newborn infant. The method comprises: (a) continuously monitoring heart rate variability in the premature newborn infant; and (b) identifying at least one characteristic abnormality in the heart rate variability that is associated with the illness. This method can be use to diagnose illnesses such as, but not limited to, sepsis, necrotizing enterocolitis, pneumonia and meningitis. In another aspect of the present invention, there is provided a method and apparatus for early detection of subacute, potentially catastrophic infectious illness in a patient.