Abstract: Various methods and systems are provided for a patient monitoring compliance system. In one embodiment, a method includes determining, over a duration, a relative amount of monitored time where data from the one or more monitoring devices was usable for monitoring one or more parameters of a patient, and if the relative amount of monitored time is less than a threshold amount of monitored time, outputting a first notification.

Abstract: A method and system for generating a treatment plan are disclosed herein. A computing system receives a plurality of dose volume histograms for a plurality of patients and a plurality of volumetric dose distributions corresponding to the plurality of dose volume histograms. The computing system generates a volumetric dose prediction model using a neural network by learning, by the neural network, a relationship between a plurality of dose volume histograms for the plurality of patients and the corresponding plurality of volumetric dose distributions. The computing system receives a candidate dose volume histogram for a target patient. The computing system infers, via the volumetric dose prediction module, a volumetric dose prediction distribution matching the candidate dose volume histogram. The computing system generates a recommendation based on the inferred volumetric dose prediction distribution.

Abstract: The present invention has an object to manage the manual ingestion (and failure of manual ingestion) of an ingestible object without making the user feel bothered. The present invention includes: a collating unit configured to collate the biological data acquired by a biosensor and the temporal changes of biological data that occur after a medicine is taken and after a medicine is not taken at a medicine-taking timing; and a warning output unit configured to output, on the basis of a result of the collation, information on whether or not a living body has taken the medicine.

Abstract: A probe of a target identification system can be extended via a first lumen of a viewing instrument, such as for illuminating an area beyond a distal end of the viewing instrument via an optical path of the viewing instrument. An optical response to the illumination of the area can be received via an optical path of the probe and can be split from other optical signals of the optical path. The optical response information can be used to identify characteristics of a target and to adjust parameters of a working instrument such as a working instrument contemporaneously using the probe.

Abstract: A method and a system for providing feedback to a user for adjusting sleep pattern of the user. The method includes collecting a set of information related to the user, receiving a set of measurement data related to the user from a wearable electronic device, defining circadian rhythm and duration of sleep of the user, determining sleep scores for a predefined number of days and associating each sleep score with a corresponding go-to-bed time or time of falling asleep of the user. A sleep score is determined for each of the predefined number of days from the collected set of information, the set of measurement data, the circadian rhythm and the duration of sleep of the user. The method further includes analysing the sleep scores and associated go-to-bed time or time of falling asleep of the user to determine an optimum bedtime window for the user and providing feedback to the user based on the analysed sleep scores and the optimum bedtime window.

Abstract: Anchoring mechanisms for an implantable electrical medical lead that is positioned within a substernal space are disclosed. The anchoring mechanisms fixedly-position a distal portion of the lead, that is implanted in the substernal space.

Abstract: A system (400) for monitoring an individual's sleep includes: (i) a patient monitor (410) configured to obtain a patient waveform, the patient waveform comprising information representative of a vital statistic of the patient; a processor (420) in communication with the patient monitor and configured to: (i) process the patient waveform to generate a segmented waveform; (ii) extract at least one feature from a segment of the waveform in a time domain and/or at least one feature from the segment of the waveform in the frequency domain; (iii) classify, using the at least one extracted feature, a sleep stage of the patient for the segment of the waveform; and (iv) generate, from classified sleep stages for a plurality of segments of the waveform, a sleep quality measurement; and a user interface (480) configured to report the generated sleep quality measurement.

Abstract: A probe of a target identification system can be extended via a first lumen of a viewing instrument, such as for illuminating an area beyond a distal end of the viewing instrument via an optical path of the viewing instrument. An optical response to the illumination of the area can be received via an optical path of the probe and can be split from other optical signals of the optical path. The optical response information can be used to identify characteristics of a target and to adjust parameters of a working instrument such as a working instrument contemporaneously using the probe.

Abstract: Described herein is a method for identifying a farm animal having an impairment of regulative capacity in response to metabolic stress, the method including: a) assessing the value of the nonlinear domain heart rate variability component LMAX of a farm animal based on a heart beat interval data set obtained for the farm animal; and b) comparing the value of LMAX assessed according to (a) with a species specific threshold of LMAX, whereby a farm animal having an impairment of regulative capacity will be identified.

Abstract: Methods, devices and program products are provided for under control of one or more processors within an implantable medical device (IMD). Sensing near field (NF) and far field (FF) signals are between first and second combinations of electrodes coupled to the IMD. The method applies an arrhythmia detection algorithm to the NF signals for identifying events within the NF signal and designates events marker based thereon and monitors the event markers to detect a candidate arrhythmia condition in the NF signals. The candidate under-detected condition comprises at least one of an under-detected arrhythmia or over-sensing. In response to detection of the candidate arrhythmia condition, the method analyzes the FF signals for a presence of an under-detected arrhythmia indicator. The method delivers an arrhythmia therapy based on the presence of the under-detected arrhythmia indicator in the FF signals and the candidate under-detected arrhythmia condition in the NF signals.

Abstract: Presented herein are techniques that enable electroporation of the cells of a recipient of a tissue-stimulating prostheses while the tissue-stimulating prosthesis is implanted in the recipient. Tissue-stimulating prostheses in accordance with embodiments presented herein are configured such that the stimulation electronics (e.g., current sources and integrated circuit) of the prosthesis are not exposed to the high voltages used in electroporation.

Abstract: A system for stimulating a sympathetic chain includes an electrode assembly that is configured to attach to a bone in proximity to a targeted portion of the sympathetic chain. The electrode assembly includes a cathode and an anode. The system also includes a power supply connected to the electrode assembly and configured to deliver power to the electrode assembly. The electrode assembly generates an electrical field between the cathode and the anode when power is delivered to the electrode assembly. The electrical field reaches the targeted portion of the sympathetic chain to provide electrical stimulation to the targeted portion of the sympathetic chain.

Abstract: A bed includes: a bed body having a space for a user to rest; a monitoring device connected to the bed body, the monitoring device including a pressure detecting mechanism, a signal processing unit electrically coupled to the pressure detecting mechanism, and a monitoring unit electrically coupled to the signal processing unit. The pressure detecting mechanism is configured to detect pressure variations of the bed body, generate pressure data, and transmit the pressure data to the signal processing unit. The signal processing unit is configured to process the pressure data and generate processed signal data. The monitoring unit is configured to monitor the processed signal data.

Abstract: A neurostimulation (NS) system and method are provided. The system includes a power supply having positive and negative terminals. The negative terminal defines a reference ground. An array of electrodes includes first and second active electrodes for delivering stimulation therapy configured to be located proximate to neural tissue of interest that is associated with a target region. A control circuit is configured to control delivery of stimulation current for a NS therapy between the first and second electrodes. A current regulator (CR) circuit is connected to, and configured to control current flow through, at least the first electrode during delivery of the stimulation therapy under direction of the control circuit. A floating power supply is connected across power supply terminals of the CR circuit. The CR circuit and floating power supply are coupled to a floating ground node that is electrically separate from the reference ground.

Abstract: A cardiovascular health assessment score, representing a working tissue flow and indicating the dependence on central and peripheral control mechanisms, is generated by the evaluation system and used to support a variety of individualized medicine and health applications. One or more of the individualized medicine and health applications may be implemented as part of the evaluation system and incorporate the cardiovascular health assessment.

Abstract: A wellness evaluation system may determine, based on data generated by a first set of sensors powered by one or more batteries of one or more ear-wearable devices, that a user of the one or more ear-wearable devices is currently in an environment that includes human-directed communication signals. If so, a second set of sensors may be activated such that the one or more batteries provides an increased amount of power to the second set of sensors. Furthermore, the wellness evaluation system may determine based on data generated by the second set of sensors, whether the user has satisfied a target level of a wellness measure. If the user has not satisfied the target level of the wellness measure, the wellness evaluation system may perform an action to encourage the user to perform one or more activities to increase an achieved level of the wellness measure.

Abstract: Systems and methods for improving kidney function. A first mechanical circulatory support system (MCS) is introduced in a patient's heart, and a second mechanical circulatory support system is introduced in a patient's inferior vena cava or renal vein. The second mechanical circulatory support system is operated while the first mechanical circulatory support system is operating. A renal parameter is monitored during. Combined operation of the two mechanical circulatory support systems results in a change in renal parameter, e.g. pressure drop in the renal vein, indicating an improvement in kidney function. Once the renal parameter is determined to be below a target threshold, operation of the second mechanical circulatory support device is stopped.

Abstract: A brain mapping system and methods that allow to predict and monitor the risk of suicide and provide personalized therapy. The brain mapping system and methods detect if brain dysfunctions (injuries) are located in suicidal hubs that trigger increased suicidal ideation and high risk of suicide. The brain mapping technology is suited for different technologies and allows to monitor the effects of therapy, provide precise therapy to decrease the risk of suicide.

Abstract: In embodiments, an external defibrillator has an electrical circuit with a special output stage for the high-voltage defibrillation pulse. The output stage includes switches that can turn on for delivering the pulse, and off during all other times. The output stage also includes a diverting resistance to divert electrical current that could leak into the patient while a capacitor is being charged. An optional detector may notify if a component is malfunctioning. An advantage can be that an external defibrillator may be created according to embodiments that uses, in its output stage, semiconductor switches instead of relays. As semiconductor switches weigh less and occupy less volume than relays, an external defibrillator according to embodiments may have less weight and volume. Especially in wearable defibrillator applications, less weight means less effort to carry and less volume means easier concealment under clothing.

Abstract: A system for detecting a suction condition in an implantable blood pump including a controller in communication with the blood pump. The controller includes a control circuit configured to calculate a present value during a time period, the present value corresponding to a pump speed divided by a pump current, determine a plurality of data values during the time period based on the present value, and determine a suction detection threshold value using the plurality of data values. The control circuit is also configured to compare the present value during the time period to the suction detection threshold value and generate an alert when the present value exceeds the suction detection threshold value on a plurality of instances during the time period, the alert corresponding to a suction condition.