Abstract: The present invention is directed to methods for inhibiting the growth or killing cell in an organism, particularly plants. Genetically engineered cells and which allow for killing or provision of a beneficial effect to specified cells are also provided.

Abstract: The present invention relates to the gene CYP76B1 of a cytochrome P450 which has been isolated from Helianthus tuberosus tuber. The expression of this gene in yeast has shown that it encoded an enzyme very actively catalysing the O-dealkylation of various exogenous molecules with a high efficiency, such as phenylureas. The expression of CYP76B1 is strongly induced in plants brought into contact with certain exogenous metals or organic compounds. This induction may be exploited for the detection of environmental pollutants. CYP76B1 can be also used to alter the resistance of plants sensitive to this family of herbicides and for soil and groundwater bioremedation.